Results 171 to 180 of about 18,065 (250)

CINPA1 Is an Inhibitor of Constitutive Androstane Receptor That Does Not Activate Pregnane X Receptor [PDF]

, 2015
Milu T. Cherian, Wenwei Lin, Jing Wu, Taosheng Chen   +3 more
openalex   +1 more source

Pregnane X receptor (PXR) as a prognostic marker and therapeutic target in kidney renal clear cell carcinoma (KIRC) via AMPK pathway regulation. [PDF]

Sci Rep
Hu WJ, Liu M, Bao YN, Su BW, Sui X, Cui XH, Wang GY, Wen L, Wen RK, Wang WH, Yang HX, Luan ZL.   +11 more
europepmc   +1 more source

Blockade of the estrogen receptor alpha-pregnane X receptor axis protects ovariectomized mice against ethanol-induced hepatotoxicity. [PDF]

J Biol Chem
Twum E, Ofosu-Boateng M, Nnamani DO, Gebreyesus LH, Yadak N, Kharbanda KK, Gonzalez FJ, Gyamfi MA.   +7 more
europepmc   +1 more source

Pregnane X Receptor and the Gut-Liver Axis: A Recent Update. [PDF]

Drug Metab Dispos, 2022
Dutta M, Lim JJ, Cui JY.
europepmc   +1 more source

Quantifying expression and metabolic activity of genes regulated by pregnane X receptor in primary human hepatocyte spheroids. [PDF]

PLoS Comput Biol
Lochman L, Kahiya ET, Saade B, Smutný T, Tebbens JD, Pávek P, Bernhauerová V.   +6 more
europepmc   +1 more source

Allosteric Antagonism of the Pregnane X Receptor (PXR): Current-State-of-the-Art and Prediction of Novel Allosteric Sites. [PDF]

Cells, 2022
Kamaraj R, Drastik M, Maixnerova J, Pavek P.   +3 more
europepmc   +1 more source

LIM and SH3 protein 2 (Lasp2) is a novel pregnane X receptor target gene in mouse liver. [PDF]

Mol Pharmacol
Konzack A, Karpale M, Smutny T, Hassanen M, Lassila P, Ahonen MH, Elkhwanky MS, Kummu O, Pavek P, Hakkola J.   +9 more
europepmc   +1 more source

Defensins and Efflux Transporters Meet Their Fate in 2008: No Major Role in the Pathogenesis of Inflammatory Bowel Disease [PDF]

, 2008
Ochsenkühn, Thomas
core   +1 more source

Strategies for developing pregnane X receptor antagonists: Implications from metabolism to cancer

, 2019
Sergio C. Chai, William C. Wright, Taosheng Chen   +2 more
openalex   +2 more sources

First-in-Class Small Molecule Degrader of Pregnane X Receptor Enhances Chemotherapy Efficacy. [PDF]

J Med Chem
Huber AD, Jung YH, Li Y, Lin W, Wu J, Poudel S, Carrigan AG, Mishra A, High AA, Chen T.   +9 more
europepmc   +1 more source