Results 221 to 230 of about 235,181 (316)

LIM and SH3 protein 2 (Lasp2) is a novel pregnane X receptor target gene in mouse liver. [PDF]

Mol Pharmacol
Konzack A, Karpale M, Smutny T, Hassanen M, Lassila P, Ahonen MH, Elkhwanky MS, Kummu O, Pavek P, Hakkola J.   +9 more
europepmc   +1 more source

Discrepancy in interactions and conformational dynamics of pregnane X receptor (PXR) bound to an agonist and a novel competitive antagonist. [PDF]

Comput Struct Biotechnol J, 2022
Rashidian A, Mustonen EK, Kronenberger T, Schwab M, Burk O, Laufer SA, Pantsar T.   +6 more
europepmc   +1 more source

Expanding the Roles for Pregnane X Receptor in Cancer: Proliferation and Drug Resistance in Ovarian Cancer [PDF]

, 2008
Divya Gupta, Madhukumar Venkatesh, Hongwei Wang, Sean Kim, Michael Sinz, Gary L. Goldberg, Kathleen D. Whitney, Clifford Longley, Sridhar Mani   +8 more
openalex   +1 more source

Association of a Single‐Nucleotide Polymorphism in the Pregnane X Receptor (PXR63396C→T) with Reduced Concentrations of Unboosted Atazanavir [PDF]

, 2008
Marco Siccardi, Antonio D’Avolio, Lorena Baietto, Sara Gibbons, Mauro Sciandra, Daniela Colucci, Stefano Bonora, Saye Khoo, David Back, Giovanni Di Perri, Andrew Owen   +10 more
openalex   +1 more source

Mice blocking Ser347 phosphorylation of pregnane x receptor develop hepatic fasting-induced steatosis and hypertriglyceridemia. [PDF]

Biochem Biophys Res Commun, 2022
Yokobori K, Gruzdev A, Negishi M.
europepmc   +1 more source

A two-in-one expression construct for biophysical and structural studies of the human pregnane X receptor ligand-binding domain, a pharmaceutical and environmental target. [PDF]

Acta Crystallogr F Struct Biol Commun
Carivenc C, Laconde G, Blanc P, Amblard M, Bourguet W, Delfosse V.   +5 more
europepmc   +1 more source

Role of nuclear pregnane X receptor in Cu-induced lipid metabolism and xenobiotic responses in largemouth bass (Micropterus salmoides). [PDF]

Front Endocrinol (Lausanne), 2022
Li H, Gong W, Wang G, Yu E, Tian J, Xia Y, Li Z, Zhang K, Xie J.   +8 more
europepmc   +1 more source

Hybrid Scoring and Classification Approaches to Predict Human Pregnane X Receptor Activators [PDF]

, 2008
Sandhya Kortagere, Dmitriy S. Chekmarev, William J. Welsh, Sean Ekins   +3 more
openalex   +1 more source

Human pregnane X receptor is expressed in breast carcinomas, potential heterodimers formation between hPXR and RXR-alpha [PDF]

, 2008
Isabel Conde, María VT Lobo, Javier Zamora, J. J. Pérez, Francisco Javier González, Emilio Alba, Benito Fraile, Ricardo Paniagua, M. Isabel Arenas   +8 more
openalex   +1 more source

QSAR development and profiling of 72,524 REACH substances for PXR activation and CYP3A4 induction [PDF]

, 2017
Abildgaard Rosenberg, Sine, Dybdahl, Marianne, Huang, R., Nikolov, Nikolai Georgiev, Wedebye, Eva Bay, Xia, M.   +5 more
core   +1 more source