Results 241 to 250 of about 235,181 (316)

Pregnane X Receptor Activation in Liver Macrophages Protects against Endotoxin-Induced Liver Injury. [PDF]

Adv Sci (Weinh)
Zhao T, Zhong G, Wang Y, Cao R, Song S, Li Y, Wan G, Sun H, Huang M, Bi H, Jiang Y.   +10 more
europepmc   +1 more source

Overcoming the Pregnane X Receptor Liability: Rational Design to Eliminate PXR-Mediated CYP Induction. [PDF]

ACS Med Chem Lett, 2021
Ramanjulu JM, Williams SP, Lakdawala AS, DeMartino MP, Lan Y, Marquis RW.   +5 more
europepmc   +1 more source

Enhanced GABAergic actions resulting from the coapplication of the steroid 3α-hydroxy-5α-pregnane-11,20-dione (alfaxalone) with propofol or diazepam [PDF]

, 2018
Akk, Gustav, Cao, Lily Q, Chakrabarti, Shampuma, Evers, Alex S, Germann, Allison L, Mennerick, Steven, Montana, Michael C, Shin, Daniel J, Wozniak, David F, Yuede, Carla M   +9 more
core   +1 more source

Cyclic AMP-dependent Protein Kinase Signaling Modulates Pregnane x Receptor Activity in a Species-specific Manner [PDF]

, 2009
Kristin Lichti-Kaiser, Chenshu Xu, Jeff L. Staudinger   +2 more
openalex   +1 more source

A Combined Approach for Rapid Dereplication of Herb-Drug Interaction Causative Agents in Botanical Extracts-A Molecular Networking Strategy To Identify Potential Pregnane X Receptor (PXR) Modulators in Yohimbe. [PDF]

ACS Omega
Annam SCVAR, Neal WM, Pandey P, Avula B, Katragunta K, Husain I, Khan SI, Koturbash I, Gurley BJ, Khan IA, Chittiboyina AG.   +10 more
europepmc   +1 more source

St. John's Wort alleviates dextran sodium sulfate-induced colitis through pregnane X receptor-dependent NFκB antagonism. [PDF]

FASEB J, 2021
Yan T, Luo Y, Xia Y, Hamada K, Wang Q, Yan N, Krausz KW, Ward JM, Hao H, Wang P, Gonzalez FJ.   +10 more
europepmc   +1 more source

The Flame Retardants, Polybrominated Diphenyl Ethers, Are Pregnane X Receptor Activators

, 2007
Erik Pacyniak, Xingguo Cheng, Michael L. Cunningham, Kevin M. Crofton, Curtis D. Klaassen, Grace L. Guo   +5 more
openalex   +1 more source

Pregnane X Receptor Signaling Pathway and Vitamin K: Molecular Mechanisms and Clinical Relevance in Human Health. [PDF]

Cells
Staudinger JL, Mahroke A, Patel G, Dattel C, Reddy S.   +4 more
europepmc   +1 more source

Regulation of Tissue-Specific Carboxylesterase Expression by Pregnane X Receptor and Constitutive Androstane Receptor [PDF]

, 2009
Chenshu Xu, Xinkun Wang, Jeff L. Staudinger   +2 more
openalex   +1 more source

S-nitrosylation attenuates pregnane X receptor hyperactivity and acetaminophen-induced liver injury. [PDF]

JCI Insight
Cui Q, Jiang T, Xie X, Wang H, Qian L, Cheng Y, Li Q, Lu T, Yao Q, Liu J, Lai B, Chen C, Xiao L, Wang N.   +13 more
europepmc   +1 more source