Results 11 to 20 of about 847 (152)

Preimplantation genetic testing [PDF]

Srpski medicinski casopis Lekarske komore, 2021
The application of preimplantation genetic testing (PGT) began in the late 1980s. Pre-implantation genetic testing, as the earliest possible method of prenatal diagnosis, enables the selection of embryos with a normal karyotype for embryo transfer. The use of preimplantation genetic testing has proven to be a useful method in the following three groups
Ana Jeremić, Dragana Vuković, Srna Subanović, Jovana Broćić, Biljana Macanović   +4 more
openaire   +3 more sources

PREIMPLANTATION GENETIC TESTING: Clinical experience of preimplantation genetic testing [PDF]

Reproduction, 2020
Abstract Thirty years of rapid technological advances in the field of genetic testing and assisted reproduction have reshaped the procedure of preimplantation genetic testing (PGT). The development of whole genome amplification and genome-wide testing tools together with the implementation of optimal hormonal stimulation protocols and
Martine, De Rycke, Veerle, Berckmoes, Anick, De Vos, Stefanie, Van De Voorde, Pieter, Verdyck, Willem, Verpoest, Kathelijn, Keymolen   +6 more
openaire   +2 more sources

PREIMPLANTATION GENETIC TESTING: Preimplantation genetic testing for polygenic disease risk [PDF]

Reproduction, 2020
Abstract Since its introduction to clinical practice, preimplantation genetic testing (PGT) has become a standard of care for couples at risk of having children with monogenic disease and for chromosomal aneuploidy to improve outcomes for patients with infertility.
Nathan R, Treff, Diego, Marin, Louis, Lello, Stephen, Hsu, Laurent C A M, Tellier   +4 more
openaire   +2 more sources

Utilization of preimplantation genetic testing in the USA [PDF]

Journal of Assisted Reproduction and Genetics, 2021
Abstract Purpose To evaluate the use of preimplantation genetic testing (PGT) and live birth rates (LBR) in the USA from 2014 to 2017 and to understand how PGT is being used at a clinic and state level. Methods This study accessed SART data for 2014 to 2017 to determine LBR ...
Kaitlyn Roche, Catherine Racowsky, Joyce Harper   +2 more
openaire   +3 more sources

Targeting myotonic dystrophy by preimplantation genetic diagnosis-karyomapping

Taiwanese Journal of Obstetrics & Gynecology, 2019
Objective: To report a case with Myotonic dystrophy type I with successful preimplantation genetic diagnosis-karyomapping. Case report: A 34-year-old female carrier of myotonic dystrophy type I was treated at our clinic with a successful pregnancy after ...
Cheng-Wei Wang, Yung-Liang Liu, Chi-Huang Chen   +2 more
doaj   +1 more source

Genetic counseling for pre-implantation genetic testing of monogenic disorders (PGT-M)

Frontiers in Reproductive Health, 2023
Pre-implantation genetic testing (PGT) is a vital tool in preventing chromosomal aneuploidies and other genetic disorders including those that are monogenic in origin. It is performed on embryos created by intracytoplasmic sperm injection (ICSI). Genetic
Firuza Parikh, Arundhati Athalye, Prochi Madon, Meenal Khandeparkar, Dattatray Naik, Rupesh Sanap, Anuradha Udumudi   +6 more
doaj   +1 more source

Preimplantation genetic testing for breast cancer

Nigerian Medical Journal, 2019
Breast cancer (BC), a malignant tumor characterized mainly by a lump in the breast and a change in breast shape, has plagued many women of childbearing age in Nigeria today. This has thus propelled many to find both prophylactic and curative agents to combat BC in affected persons.
Oribamise, Eunice I., Ashiru, Oladapo A., Iloabachie, Ebele C., Osumah, Jumoke G., Moruf, Oladimeji O.   +4 more
openaire   +3 more sources

De novo balanced reciprocal translocation mosaic t(1;3)(q42;q25) detected by prenatal genetic diagnosis: a fetus conceived using preimplantation genetic testing due to a t(12;14)(q22;q13) balanced paternal reciprocal translocation

Molecular Cytogenetics, 2021
Introduction De novo balanced reciprocal translocations mosaicism in fetus conceived using preimplantation genetic testing from a different balanced translocation carrier parent has been rarely reported. Methods Chromosomal microarray analysis, karyotype
Shaoqin Zhang, Jianjiang Zhu, Hong Qi, Limei Xu, Lirong Cai, Ran Meng   +5 more
doaj   +1 more source

Evolution and utility of preimplantation genetic testing for monogenic disorders in assisted reproduction - A narrative review

Journal of Human Reproductive Sciences, 2021
Preimplantation genetic testing (PGT) for monogenic disorders and assisted reproductive technology have evolved and progressed in tandem. PGT started with single-cell polymerase chain reaction (PCR) followed by fluorescent in situ hybridisation for a ...
Firuza R Parikh, Arundhati S Athalye, Dhananjaya K Kulkarni, Rupesh R Sanap, Suresh B Dhumal, Dhanashree J Warang, Dattatray J Naik, Prochi F Madon   +7 more
doaj   +1 more source

Past, Present, and Future Strategies for Enhanced Assessment of Embryo's Genome and Reproductive Competence in Women of Advanced Reproductive Age

Frontiers in Endocrinology, 2019
Recent advancements in genomic analysis allow testing of an increasing number of genetic features in human preimplantation embryos. Typical single gene mutation and whole chromosomes testing can now be integrated with assessment of mitochondrial DNA and ...
Maurizio Poli, Maurizio Poli, Laura Girardi, Marco Fabiani, Martina Moretto, Valeria Romanelli, Cristina Patassini, Daniela Zuccarello, Antonio Capalbo, Antonio Capalbo, Antonio Capalbo   +10 more
doaj   +1 more source