Results 21 to 30 of about 847 (152)

Molar pregnancy after in vitro fertilization with euploid single embryo transfer

F&S Reports, 2021
Objective: To describe a case of molar pregnancy after in vitro fertilization (IVF) resulting from the transfer of a euploid embryo derived from a monopronuclear zygote. Design: Case report and review of the literature.
Beth Zhou, M.D., Helen Paige Anglin, M.D., Alexander M. Quaas, M.D., Ph.D.   +2 more
doaj   +1 more source

Implementation of Noninvasive Preimplantation Genetic Testing for Aneuploidy with Spent Blastocyst Medium into Clinical and Laboratory Practice: The First Successful Experience in Taiwan

Fertility & Reproduction, 2023
Noninvasive preimplantation genetic testing for aneuploidy (niPGT-A) using cell-free DNA (cfDNA) present in the spent blastocyst medium (SBM) of human blastocysts has emerged as an alternative for classical preimplantation genetic testing for aneuploidy (
Chun-Kai Chen, Wei-Han Huang, Tiencheng Arthur Chang, Kuang-Han Chao, Wang-Fung Chiang, Hsin-Yi Yeh, Szu-Yu Shen   +6 more
doaj   +1 more source

Preimplantation Genetic Testing [PDF]

Current Obstetrics and Gynecology Reports, 2013
The application of genetic technologies to the field of reproductive medicine has ushered in a new era of medicine that is likely to greatly expand in the coming years. Concurrent with an in vitro fertilization (IVF) cycle, it is now possible to obtain a cellular biopsy from a developing embryo and genetically evaluate this sample with increasing ...
Paul R. Brezina, Patrick Jaeger, Michael A. Kutteh, William G. Kearns   +3 more
openaire   +1 more source

Mosaicism in preimplantation human embryos

Интегративная физиология, 2020
Since the very first publications on preimplantation genetic testing, researchers have faced a serious problem — a high mosaicism level in the preimplantation human embryos obtained by means of in vitro fertilization cycles.
Алсу Фаритовна Сайфитдинова, Олег Сергеевич Глотов, Ирина Васильевна Полякова, Наталья Константиновна Бичевая, Юлия Артемьевна Логинова, Рена Алескеровна Кузнецова, Ольга Анатольевна Леонтьева, Елизавета Евгеньевна Невская, Ольга Андреевна Павлова, Ирина Леонидовна Пуппо, Антон Евгеньевич Шиков, Станислав Петрович Уразов, Татьяна Владимировна Кузнецова, Андрей Михайлович Сарана, Сергей Григорьевич Щербак, Владислав Сергеевич Баранов   +15 more
doaj   +1 more source

Non-invasive preimplantation genetic testing for conventional IVF blastocysts

Journal of Translational Medicine, 2022
Background Previous studies suggested that non-invasive preimplantation genetic testing (niPGT) for intracytoplasmic sperm injection (ICSI) blastocysts can be used to identify chromosomal ploidy and chromosomal abnormalities.
Pingyuan Xie, Shuoping Zhang, Yifang Gu, Bo Jiang, Liang Hu, Yue-qiu Tan, Yaxin Yao, Yi Tang, Anqi Wan, Sufen Cai, Yangyun Zou, Guangxiu Lu, Cheng Wan, Fei Gong, Sijia Lu, Ge Lin   +15 more
doaj   +1 more source

Preimplantation genetic testing for Marfan syndrome [PDF]

Molecular Human Reproduction, 1996
Marfan syndrome (MFS) is an autosomal dominant disease that affects the skeletal, ocular and cardiovascular systems. Defects in the gene that codes for fibrillin (FBN-1) are responsible for MFS. Here we report the world's first use of preimplantation genetic testing (PGT) to achieve a clinical pregnancy and live birth of a baby free of a Marfan ...
G L, Harton, P, Tsipouras, M E, Sisson, K M, Starr, B S, Mahoney, E F, Fugger, J D, Schulman, M W, Kilpatrick, G, Levinson, S H, Black   +9 more
openaire   +2 more sources

Preimplantation Genetic Testing for Monogenic Disorders [PDF]

Genes, 2020
Preimplantation genetic testing (PGT) has evolved into a well-established alternative to invasive prenatal diagnosis, even though genetic testing of single or few cells is quite challenging. PGT-M is in theory available for any monogenic disorder for which the disease-causing locus has been unequivocally identified. In practice, the list of indications
De Rycke, Martine, Berckmoes, Veerle
openaire   +3 more sources

Ovarian stimulation for preimplantation genetic testing [PDF]

Reproduction, 2019
Abstract A narrative review of the management of controlled ovarian stimulation in patients undergoing preimplantation genetic testing is presented. An electronic search was performed to identify research publications that addressed ovarian stimulation and preimplantation genetic testing published until December 2017.
Jorge, Rodriguez-Purata, Francisca, Martinez   +1 more
openaire   +2 more sources

Preimplantation genetic testing for aneuploidy: challenges in clinical practice

Human Genomics, 2022
Preimplantation genetic testing for aneuploidy (PGT-A) has been used widely during in vitro fertilization procedures in assisted reproductive centers throughout the world.
Hui Yang, Andrew Thomas DeWan, Mayur M. Desai, Sten H. Vermund   +3 more
doaj   +1 more source

Preimplantation Genetic Testing for Single Gene Conditions and Aneuploidy

Fertility & Reproduction, 2023
It is now over 30 years since the first pregnancies and live births following IVF, embryo biopsy and preimplantation genetic testing (PGT) were reported in 1990. Since then, methods for genetic analysis at the single-cell level have evolved alongside the
Alan Handyside
doaj   +1 more source