Results 21 to 30 of about 4,572,851 (176)

A ‘healthy baby’: The double imperative of preimplantation genetic diagnosis [PDF]

, 2010
This is the author's accepted manuscript. The final published article is available from the link below. Copyright @ 2010 The Authors.This article reports from a study exploring the social processes, meanings and institutions that frame and produce ...
Williams, C, Ehrich, K, Ehrich, Kathryn, Williams, Clare   +3 more
core   +1 more source

Preimplantation genetic testing for breast cancer

Nigerian Medical Journal, 2019
Breast cancer (BC), a malignant tumor characterized mainly by a lump in the breast and a change in breast shape, has plagued many women of childbearing age in Nigeria today. This has thus propelled many to find both prophylactic and curative agents to combat BC in affected persons.
Oribamise, Eunice I., Ashiru, Oladapo A., Iloabachie, Ebele C., Osumah, Jumoke G., Moruf, Oladimeji O.   +4 more
openaire   +3 more sources

Preimplantation Genetic Testing for Genetic Diseases: Limits and Review of Current Literature

, 2023
Preimplantation genetic testing (PGT) has emerged as a revolutionary technique in the field of reproductive medicine, allowing for the selection and transfer of healthy embryos, thus reducing the risk of transmitting genetic diseases.
Ugo Sorrentino, Angela Vallefuoco, Roberta Giuliano, Daniela Zuccarello, Anna Maione   +4 more
core   +1 more source

Live birth after single euploid frozen embryo transfer in a 39-year-old woman with high-grade mosaic Turner syndrome

The Journal of Maternal-Fetal & Neonatal Medicine, 2023
Objective To describe the reproductive and obstetric outcomes of an intracytoplasmic sperm injection cycle with preimplantation genetic testing for aneuploidy in an advanced reproductive-age woman with high-grade mosaic Turner syndrome.Methods Case ...
Giuliano Bedoschi, Guilherme Gastaldo, Bianca Bianco, Denise Maria Christofolini, Caio Parente Barbosa, Matheus Roque, Paula Andrea Navarro   +6 more
doaj   +1 more source

Past, Present, and Future Strategies for Enhanced Assessment of Embryo's Genome and Reproductive Competence in Women of Advanced Reproductive Age

Frontiers in Endocrinology, 2019
Recent advancements in genomic analysis allow testing of an increasing number of genetic features in human preimplantation embryos. Typical single gene mutation and whole chromosomes testing can now be integrated with assessment of mitochondrial DNA and ...
Maurizio Poli, Maurizio Poli, Laura Girardi, Marco Fabiani, Martina Moretto, Valeria Romanelli, Cristina Patassini, Daniela Zuccarello, Antonio Capalbo, Antonio Capalbo, Antonio Capalbo   +10 more
doaj   +1 more source

De novo balanced reciprocal translocation mosaic t(1;3)(q42;q25) detected by prenatal genetic diagnosis: a fetus conceived using preimplantation genetic testing due to a t(12;14)(q22;q13) balanced paternal reciprocal translocation

Molecular Cytogenetics, 2021
Introduction De novo balanced reciprocal translocations mosaicism in fetus conceived using preimplantation genetic testing from a different balanced translocation carrier parent has been rarely reported. Methods Chromosomal microarray analysis, karyotype
Shaoqin Zhang, Jianjiang Zhu, Hong Qi, Limei Xu, Lirong Cai, Ran Meng   +5 more
doaj   +1 more source

Genetic counseling for pre-implantation genetic testing of monogenic disorders (PGT-M)

Frontiers in Reproductive Health, 2023
Pre-implantation genetic testing (PGT) is a vital tool in preventing chromosomal aneuploidies and other genetic disorders including those that are monogenic in origin. It is performed on embryos created by intracytoplasmic sperm injection (ICSI). Genetic
Firuza Parikh, Arundhati Athalye, Prochi Madon, Meenal Khandeparkar, Dattatray Naik, Rupesh Sanap, Anuradha Udumudi   +6 more
doaj   +1 more source

Evolution and utility of preimplantation genetic testing for monogenic disorders in assisted reproduction - A narrative review

Journal of Human Reproductive Sciences, 2021
Preimplantation genetic testing (PGT) for monogenic disorders and assisted reproductive technology have evolved and progressed in tandem. PGT started with single-cell polymerase chain reaction (PCR) followed by fluorescent in situ hybridisation for a ...
Firuza R Parikh, Arundhati S Athalye, Dhananjaya K Kulkarni, Rupesh R Sanap, Suresh B Dhumal, Dhanashree J Warang, Dattatray J Naik, Prochi F Madon   +7 more
doaj   +1 more source

Next generation sequencing for preimplantation genetic testing of blastocysts aneuploidies in women of different ages [PDF]

, 2015
Most of the current preimplantation genetic screening of aneuploidies tests are based on the low quality and low density comparative genomic hybridization arrays. The results are based on fewer than 2,700 probes.
Krzysztof Lukaszuk, Jakiel, G., Plociennik, L., Joanna Liss, Ewa Pastuszek, Waldemar Kuczynski, Aron Lukaszuk, Pastuszek, E., Lukaszuk, K., Pukszta, S., Grzegorz Jakiel, Lukasz Plociennik, Liss, J., Sebastian Pukszta, Kuczynski, W., Lukaszuk, A.   +15 more
core   +2 more sources

Social welfare, genetic welfare? Boundary-work in the IVF/PGD clinic [PDF]

, 2006
Copyright @ 2006 Elsevier Ltd. All rights reserved.Through the lens of the ‘welfare of the child’ assessment, this paper explores how staff working in the area of in vitro fertilisation and preimplantation genetic diagnosis (IVF/PGD) balance reflexive ...
Williams, C, Sandall, Jane; id_orcid, Scott, R, Farsides, Bobbie, Ehrich, K, Ehrich, Kathryn, Williams, Clare, Farsides, B, Scott, Rosamund, Sandall, J, Sandall, Jane   +10 more
core   +1 more source