Results 41 to 50 of about 4,572,851 (176)

Non-invasive and invasive preimplantation genetic testing workflow.

, 2018
Non-invasive and invasive preimplantation genetic testing workflow.
Ran Antes (417275), Gelareh Motamedi (5204534), Svetlana Madjunkova (658226), Rina Abramov (5204528), Zenon Ibarrientos (5204531), Clifford Librach (3751186), Valeriy Kuznyetsov (4093663)   +6 more
core   +1 more source

Prêt-à-Porter Procreation: Contemplating the Ban on Preimplantation Sex Selection

Potchefstroom Electronic Law Journal, 2019
Preimplantation genetic testing makes it possible to genetically test in vitro embryos for the presence of genetic disease. It also identifies the sex of the embryo.
Sheetal Soni
doaj   +1 more source

Preimplantation Genetic Testing: Indications and Controversies [PDF]

Clinics in Laboratory Medicine, 2010
In the last two decades, the use of preimplantation genetic testing has increased dramatically. This testing is used for identifying singlegene disorders, chromosomal abnormalities, mitochondrial disorders, gender selection in non-mendelian disorders with unequal gender distribution, aneuploidy screening, and other preconceptually identified genetic ...
Amber R, Cooper, Emily S, Jungheim
openaire   +2 more sources

Indications for Preimplantation Genetic Testing for Aneuploidy (PGT-A).

, 2018
Indications for Preimplantation Genetic Testing for Aneuploidy (PGT-A).
Rupali Chopra (246435), Barbara Lawrenz (3990386), Human M. Fatemi (3990392), Alberto Liñán (5675405), Ana Arnanz (5675414), Asina Bayram (5675411), Ibrahim El Khatib (5675408), Carmen Rubio (500711)   +7 more
core   +1 more source

Preimplantation Genetic Testing for Single Gene Conditions and Aneuploidy

Fertility & Reproduction, 2023
It is now over 30 years since the first pregnancies and live births following IVF, embryo biopsy and preimplantation genetic testing (PGT) were reported in 1990. Since then, methods for genetic analysis at the single-cell level have evolved alongside the
Alan Handyside
doaj   +1 more source

Application of microdeletion and microduplication screening in preimplantation genetic testing: a case report

Journal of Medical Case Reports
Background Microdeletions and microduplications are chromosomal variants ranging up to 3 Mb in size. These abnormalities often arise spontaneously and have significant clinical implications, including developmental delay and congenital anomalies.
Maria Katz, Ben Podgursky, Shenglai Li, Qinnan Zhang, Daniel Shapiro, Monica Pasternak, Noor Siddiqui, Funda Suer, Yuntao Xia   +8 more
doaj   +1 more source

Preimplantation genetic testing for aneuploidy: challenges in clinical practice

Human Genomics, 2022
Preimplantation genetic testing for aneuploidy (PGT-A) has been used widely during in vitro fertilization procedures in assisted reproductive centers throughout the world.
Hui Yang, Andrew Thomas DeWan, Mayur M. Desai, Sten H. Vermund   +3 more
doaj   +1 more source

NICE: A Two‐Step Non‐Invasive Framework for Embryo cfDNA Read Enrichment and Quality Assessment

Advanced Science, EarlyView.
The non‐invasive NICE framework, built on an ensemble stacking machine learning model, prioritizes embryos by analyzing cell‐free DNA from spent culture medium. By integrating multimodal signals, including genomic and epigenetic profiles, this automated approach standardizes morphological assessment without human bias, paving the way for more precise ...
Xueya Zhou, Shu Ding, Zhenyi Zhang, Qiaoling Shangguan, Jie Qiao, Peijie Zhou, Yidong Chen   +6 more
wiley   +1 more source

Optimized Cas9‐Enriched Nanopore Sequencing and Analysis Workflow for Clinical Diagnosis of Repeat Expansion Disorders

Advanced Science, EarlyView.
An optimized Cas9‐enriched nanopore sequencing workflow, combined with STRiker, enables simultaneous analysis of disease‐associated STR loci from patient blood. The nCATS–STRiker workflow detects repeat expansions, de novo repeat motifs, interruption patterns, and methylation in a single assay, improving the genetic diagnosis of previously undiagnosed ...
Seungbok Lee, Chanju Jung, Minjeong Kim, Narae Kim, Gue‐Ho Hwang, Soon‐Tae Lee, Kon Chu, Sang Kun Lee, Han‐Joon Kim, Jong‐Hee Chae, Sangsu Bae, Jangsup Moon   +11 more
wiley   +1 more source

Preimplantation genetic testing guidelines of International Society of Reproductive Genetics [PDF]

, 2022
The International Society of Reproductive Genetics (ISRG) assembled a workgroup made up of clinicians, clinical laboratory directors, and scientists for the purpose of creating the guidelines for preimplantation genetic testing (PGT). The most up-to-date
Yan-Ting Wu, Johan Smitz, Xu, Chen-Ming, Ge Lin, Bill Yee, Chen, Zi-Jiang, He-Feng Huang, Thornhill, Alan R., Liu, Ping, Yi-Ping Shen, Zhi-Hong Yang, Zhang, Jing-Lan, Yun-Xia Cao, Song-Chang Chen, Yang, Zhi-Hong, Lu, Si-Jia, Huang, He-Feng, Ling-Qian Wu, Jie Qiao, Zhang, Dan, Beltsos, Angie N., Angie N. Beltsos, Xu, Cong-Jian, Kushnir, Vitaly A., Jia-Yin Liu, Wu, Ling-Qian, Chen, Song-Chang, Handyside, Alan H, Zi-Jiang Chen, Jin, Fan, Wu, Yan-Ting, Lin, Ge, Zhu, Yi-Min, Liu, Jia-Yin, Chen-Ming Xu, Shen, Yi-Ping, Alan Thornhill, Ping Liu, Fan Jin, Smitz, Johan, Yuan Gao, Jing-Lan Zhang, Vitaly A. Kushnir, Si-Jia Lu, Alan Handyside, Yi-Min Zhu, Qiao, Jie, Cao, Yun-Xia, Dan Zhang, Gao, Yuan, Frattarelli, John, Yee, Bill, Cong-Jian Xu, John Frattarelli   +53 more
core   +1 more source