Results 31 to 40 of about 22,914 (233)
Noninvasive preimplantation genetic testing for aneuploidy (niPGT-A) using cell-free DNA (cfDNA) present in the spent blastocyst medium (SBM) of human blastocysts has emerged as an alternative for classical preimplantation genetic testing for aneuploidy (
Chun-Kai Chen +6 more
doaj +1 more source
The new (liberal) eugenics [PDF]
Despite the Nazi horrors, in 1953 the new eugenics was founded, when Watson and Crick postulated the double helix of DNA as the basis of chemical heredity.
Jeremy Gibbons, Nicolas Wu, Ralf Hinze
core +2 more sources
Mosaicism in preimplantation human embryos
Since the very first publications on preimplantation genetic testing, researchers have faced a serious problem — a high mosaicism level in the preimplantation human embryos obtained by means of in vitro fertilization cycles.
Алсу Фаритовна Сайфитдинова +15 more
doaj +1 more source
Non-invasive preimplantation genetic testing for conventional IVF blastocysts
Background Previous studies suggested that non-invasive preimplantation genetic testing (niPGT) for intracytoplasmic sperm injection (ICSI) blastocysts can be used to identify chromosomal ploidy and chromosomal abnormalities.
Pingyuan Xie +15 more
doaj +1 more source
STR profiling and Copy Number Variation analysis on single, preserved cells using current Whole Genome Amplification methods [PDF]
The growing interest in liquid biopsies for cancer research and cell-based non-invasive prenatal testing (NIPT) invigorates the need for improved single cell analysis.
Cornelis, Senne +5 more
core +2 more sources
The improvement of the best practice guidelines for preimplantation genetic diagnosis of cystic fibrosis: toward an international consensus [PDF]
Cystic fibrosis (CF) is one of the most common indications for preimplantation genetic diagnosis (PGD) for single gene disorders, giving couples the opportunity to conceive unaffected children without having to consider termination of pregnancy. However,
Claustres, M +17 more
core +1 more source
Preimplantation Genetic Testing
ABSTRACT: Preimplantation genetic testing comprises a group of genetic assays used to evaluate embryos before transfer to the uterus. Preimplantation genetic testing-monogenic is targeted to single gene disorders, and preimplantation genetic testing-aneuploidy is a broader test that screens for aneuploidy in all chromosomes, including the 22 ...
+8 more sources
Endometrial stromal cells of women with recurrent miscarriage fail to discriminate between high- and low-quality human embryos [PDF]
Background The aetiology of recurrent miscarriage (RM) remains largely unexplained. Women with RM have a shorter time to pregnancy interval than normally fertile women, which may be due to more frequent implantation of non-viable embryos.
AJ Wilcox +35 more
core +3 more sources
A Right to Choose?: Sex Selection in the International Context [PDF]
While there is some debate among doctors, ethicists, and the general public about the level of medical necessity that should justify a sex-selection procedure, most accept that sex selection for medical reasons is beyond ethical reproach, and in some ...
Bumgarner, Ashley
core +2 more sources
Preimplantation genetic testing for aneuploidy: challenges in clinical practice
Preimplantation genetic testing for aneuploidy (PGT-A) has been used widely during in vitro fertilization procedures in assisted reproductive centers throughout the world.
Hui Yang +3 more
doaj +1 more source

