Conventional IVF is feasible in preimplantation genetic testing for aneuploidy [PDF]
To investigate the feasibility of the application of conventional in vitro fertilization (cIVF) for couples undergoing preimplantation genetic testing for aneuploidies (PGT-A) with non-male factor infertility.To evaluate the efficiency of sperm whole-genome amplification (WGA), spermatozoa were subjected to three WGA protocols: Picoplex, ChromInst, and
Shuoping Zhang +12 more
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Preimplantation genetic testing for aneuploidy: predictive embryonic factors [PDF]
In a preimplantation genetic testing for aneuploidy (PGT-A) cycle, does the blastocyst quality before biopsy, or the day of biopsy, or the embryo hatching status have an impact on either euploidy or the rate of embryo survival after freezing?This was a retrospective study including 6130 biopsied blastocysts coming from 1849 PGT-A cycles performed in ...
Mireia Florensa +3 more
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A systematic review on concurrent aneuploidy screening and preimplantation genetic testing for hereditary disorders: What is the prevalence of aneuploidy and is there a clinical effect from aneuploidy screening? [PDF]
INTRODUCTION: In assisted reproductive technology, aneuploidy is considered a primary cause of failed embryo implantation. This has led to the implementation of preimplantation genetic testing for aneuploidy in some clinics.
Christian Liebst Frisk Toft +2 more
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Preimplantation Genetic Testing for Aneuploidy: Current Perspectives
Seminars in Reproductive Medicine, 2021AbstractDespite improvements in assisted reproduction techniques (ARTs), live birth rates remain suboptimal, particularly in women with advanced maternal age (AMA). The leading cause of poor reproductive outcomes demonstrated in women with AMA, as well as women with recurrent miscarriage and repetitive implantation failure, is thought to be due to high
Ariadne L'Heveder +4 more
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Preimplantation Genetic Testing for Aneuploidy
Obstetrics & Gynecology, 2021Preimplantation genetic testing for aneuploidy was developed as an invasive embryo-selection technique and is extensively used in in vitro fertilization (IVF) cycles. Around 95,000 preimplantation genetic testing cycles were carried out in the United States between 2014 and 2016, the majority of which were performed for aneuploidy.
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Preimplantation Genetic Testing for Aneuploidy: A Review
Obstetrical & Gynecological Survey, 2019Importance Preimplantation genetic testing for aneuploidy (PGT-A) has undergone many technical developments over recent years, including changes in biopsy timings, methodology, and genetic analysis techniques. The evidence surrounding the efficaciousness of PGT-A is sporadic and inconsistent; as such, significant doubt and ...
James M, Kemper +2 more
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Semiconductor Sequencing for Preimplantation Genetic Testing for Aneuploidy
Journal of Visualized Experiments, 2019Chromosomal aneuploidy, one of the main causes leading to embryonic development arrest, implantation failure, or pregnancy loss, has been well documented in human embryos. Preimplantation genetic testing for aneuploidy (PGT-A) is a genetic test that significantly improves reproductive outcomes by detecting chromosomal abnormalities of embryos.
Baoheng, Gui +9 more
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The impact of preimplantation genetic testing for aneuploidy on prenatal screening
Journal of Perinatal Medicine, 2021Abstract Objectives To determine whether preimplantation genetic testing for aneuploidy (PGT-A) is associated with a reduced risk of abnormal conventional prenatal screening results in singleton pregnancies conceived using in vitro fertilization (IVF).
Moti Gulersen +9 more
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Preimplantation genetic testing for aneuploidy (PGT-A)—a single-center experience
Journal of Assisted Reproduction and Genetics, 2022The aim of this study was to determine the prevalence and nature of human embryonic aneuploidy based on the preimplantation genetic testing for aneuploidy (PGT-A), the distribution of aneuploidy across the individual chromosomes, and their relationship to maternal age.This is a retrospective cohort study conducted at a single center. The study includes
Jiny Nair +10 more
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Impact of preimplantation genetic testing for aneuploidy on obstetrical practice
Current Opinion in Obstetrics & Gynecology, 2019Purpose of review To provide updated information on preimplantation genetic testing for aneuploidy (PGT-A), focusing on its implications on prenatal diagnostic approaches after transferal of mosaic aneuploid embryos. Recent findings PGT-A is a technology to screen for chromosome ...
Yiu-Man, Chan +2 more
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