Results 161 to 170 of about 4,054 (204)

Conventional IVF is feasible in preimplantation genetic testing for aneuploidy [PDF]

open access: yesJournal of Assisted Reproduction and Genetics, 2023
To investigate the feasibility of the application of conventional in vitro fertilization (cIVF) for couples undergoing preimplantation genetic testing for aneuploidies (PGT-A) with non-male factor infertility.To evaluate the efficiency of sperm whole-genome amplification (WGA), spermatozoa were subjected to three WGA protocols: Picoplex, ChromInst, and
Shuoping Zhang   +12 more
openaire   +3 more sources

Preimplantation genetic testing for aneuploidy: predictive embryonic factors [PDF]

open access: yesJournal of Assisted Reproduction and Genetics
In a preimplantation genetic testing for aneuploidy (PGT-A) cycle, does the blastocyst quality before biopsy, or the day of biopsy, or the embryo hatching status have an impact on either euploidy or the rate of embryo survival after freezing?This was a retrospective study including 6130 biopsied blastocysts coming from 1849 PGT-A cycles performed in ...
Mireia Florensa   +3 more
openaire   +3 more sources

A systematic review on concurrent aneuploidy screening and preimplantation genetic testing for hereditary disorders: What is the prevalence of aneuploidy and is there a clinical effect from aneuploidy screening? [PDF]

open access: yesActa Obstetricia Et Gynecologica Scandinavica, 2020
INTRODUCTION: In assisted reproductive technology, aneuploidy is considered a primary cause of failed embryo implantation. This has led to the implementation of preimplantation genetic testing for aneuploidy in some clinics.
Christian Liebst Frisk Toft   +2 more
exaly   +2 more sources

Preimplantation Genetic Testing for Aneuploidy: Current Perspectives

Seminars in Reproductive Medicine, 2021
AbstractDespite improvements in assisted reproduction techniques (ARTs), live birth rates remain suboptimal, particularly in women with advanced maternal age (AMA). The leading cause of poor reproductive outcomes demonstrated in women with AMA, as well as women with recurrent miscarriage and repetitive implantation failure, is thought to be due to high
Ariadne L'Heveder   +4 more
openaire   +2 more sources

Preimplantation Genetic Testing for Aneuploidy

Obstetrics & Gynecology, 2021
Preimplantation genetic testing for aneuploidy was developed as an invasive embryo-selection technique and is extensively used in in vitro fertilization (IVF) cycles. Around 95,000 preimplantation genetic testing cycles were carried out in the United States between 2014 and 2016, the majority of which were performed for aneuploidy.
openaire   +2 more sources

Preimplantation Genetic Testing for Aneuploidy: A Review

Obstetrical & Gynecological Survey, 2019
Importance Preimplantation genetic testing for aneuploidy (PGT-A) has undergone many technical developments over recent years, including changes in biopsy timings, methodology, and genetic analysis techniques. The evidence surrounding the efficaciousness of PGT-A is sporadic and inconsistent; as such, significant doubt and ...
James M, Kemper   +2 more
openaire   +2 more sources

Semiconductor Sequencing for Preimplantation Genetic Testing for Aneuploidy

Journal of Visualized Experiments, 2019
Chromosomal aneuploidy, one of the main causes leading to embryonic development arrest, implantation failure, or pregnancy loss, has been well documented in human embryos. Preimplantation genetic testing for aneuploidy (PGT-A) is a genetic test that significantly improves reproductive outcomes by detecting chromosomal abnormalities of embryos.
Baoheng, Gui   +9 more
openaire   +2 more sources

The impact of preimplantation genetic testing for aneuploidy on prenatal screening

Journal of Perinatal Medicine, 2021
Abstract Objectives To determine whether preimplantation genetic testing for aneuploidy (PGT-A) is associated with a reduced risk of abnormal conventional prenatal screening results in singleton pregnancies conceived using in vitro fertilization (IVF).
Moti Gulersen   +9 more
openaire   +2 more sources

Preimplantation genetic testing for aneuploidy (PGT-A)—a single-center experience

Journal of Assisted Reproduction and Genetics, 2022
The aim of this study was to determine the prevalence and nature of human embryonic aneuploidy based on the preimplantation genetic testing for aneuploidy (PGT-A), the distribution of aneuploidy across the individual chromosomes, and their relationship to maternal age.This is a retrospective cohort study conducted at a single center. The study includes
Jiny Nair   +10 more
openaire   +2 more sources

Impact of preimplantation genetic testing for aneuploidy on obstetrical practice

Current Opinion in Obstetrics & Gynecology, 2019
Purpose of review To provide updated information on preimplantation genetic testing for aneuploidy (PGT-A), focusing on its implications on prenatal diagnostic approaches after transferal of mosaic aneuploid embryos. Recent findings PGT-A is a technology to screen for chromosome ...
Yiu-Man, Chan   +2 more
openaire   +2 more sources

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