Results 61 to 70 of about 3,344 (173)

Assisted Reproductive Technology in Japan: A Summary Report for 2023 by the Committee on Professional Scientific Conduct and Clinical Ethics of the Japan Society of Obstetrics and Gynecology

Reproductive Medicine and Biology, Volume 25, Issue 1, January/December 2026.
In 2023, the second year of insurance coverage, the registry recorded the highest numbers of treatment cycles and newborns. Effective registry systems planned for 2026 will enable comprehensive evaluation of emerging trends in Japanese ART practice. ABSTRACT Purpose To summarize assisted reproductive technology (ART) data for 2023 collected through the
Yukiko Katagiri, Seung Chik Jwa, Akira Kuwahara, Takeshi Iwasa, Masanori Ono, Keiichi Kato, Hiroshi Kishi, Yoshimitsu Kuwabara, Fuminori Taniguchi, Miyuki Harada, Akira Iwase, Norihiro Sugino   +11 more
wiley   +1 more source

Successful Live Birth Following PGT‐SR in a Couple Who Were Both Carriers of Balanced Reciprocal Translocations Identified During Recurrent Pregnancy Loss Workup: A Case Report

Reproductive Medicine and Biology, Volume 25, Issue 1, January/December 2026.
ABSTRACT Case A non‐consanguineous couple with recurrent pregnancy loss was found to be carriers of two different balanced reciprocal translocations: 46,XX,t(13;16)(q14;q23) and 46,XY,t(4;12)(q21.1;q15). They underwent IVF with PGT‐SR, from which seven blastocysts were obtained.
Hiroaki Negishi, Daisuke Higeta, Satoh Maki, Setsuko Satoh, Youko Matsumiya, Nanami Takano, Hidemi Yokota, Mikako Yokota, Yoshimasa Yokota   +8 more
wiley   +1 more source

Next generation sequencing for preimplantation genetic testing of blastocysts aneuploidies in women of different ages

Annals of Agricultural and Environmental Medicine, 2015
Most of the current preimplantation genetic screening of aneuploidies tests are based on the low quality and low density comparative genomic hybridization arrays. The results are based on fewer than 2,700 probes.
Krzysztof Lukaszuk, Grzegorz Jakiel, Waldemar Kuczynski, Sebastian Pukszta, Joanna Liss, Lukasz Plociennik, Aron Lukaszuk, Ewa Pastuszek   +7 more
doaj   +1 more source

Preimplantation Genetic Testing for Chromosomal Abnormalities: Aneuploidy, Mosaicism, and Structural Rearrangements [PDF]

Genes, 2020
There is a high incidence of chromosomal abnormalities in early human embryos, whether they are generated by natural conception or by assisted reproductive technologies (ART). Cells with chromosomal copy number deviations or chromosome structural rearrangements can compromise the viability of embryos; much of the naturally low human fecundity as well ...
openaire   +2 more sources

From the Understanding of Maternal Molecules and Mechanisms to Predicting Embryonic Development

Reproductive Medicine and Biology, Volume 25, Issue 1, January/December 2026.
ABSTRACT Background Embryo quality is a critical determinant of successful outcomes in assisted reproductive technology (ART). Various molecular and cellular mechanisms in oocytes influence embryo quality, and their understanding can lead to the establishment of selection criteria for enhancing implantation rates. Methods This review summarizes current
Yubao Wei, Akihiro Inoue, Kei Miyamoto
wiley   +1 more source

Caffeine Supplementation Enhances Aged Human Oocyte Quality and Embryo Development in In Vitro Fertilization: A Retrospective Paired Study

Reproductive Medicine and Biology, Volume 25, Issue 1, January/December 2026.
Caffeine supplementation before fertilization is associated with improved spindle integrity, euploidy rates, and embryo quality in oocytes from aged women, with favorable clinical and neonatal outcomes, suggesting a simple and low‐cost strategy that may support IVF outcomes, particularly in older patients or those with repeated IVF failures.
Jinkyeong Ha, Soyoung Kim, Hyunmee Jang, Yoo Ra Ko, Seyul Han, Woo Sik Lee, Jin Hee Eum   +6 more
wiley   +1 more source

Impact of Inner Cell Mass Hatching Levels Before Vitrification on Clinical Pregnancy in Preimplantation Genetic Testing for Euploidy Cycles

Reproductive Medicine and Biology, Volume 25, Issue 1, January/December 2026.
This graphical abstract illustrates that the ICM hatching level before vitrification is a significant predictor of implantation success in PGT‐A cycles. Specifically, blastocysts with an ICM hatching level of ≤ 50% are associated with higher clinical pregnancy rates, whereas those exceeding 50% show a markedly lower implantation potential.
Hsiu‐Hui Chen, Chien‐Hong Chen, Chun‐Chia Huang, Pin Yao Lin, Tsung‐Hsien Lee, Ming‐Jer Chen, Maw‐Sheng Lee, Chun‐I Lee   +7 more
wiley   +1 more source

Expanding the horizons of embryo screening: performance and case studies of preimplantation genetic testing via whole genome sequencing

Academia Molecular Biology and Genomics
Conventional preimplantation genetic testing for aneuploidy (PGT-A) and for monogenic disorders (PGT-M) is very limited in scope. These methods typically assess chromosomal ploidy or target only one or two specific variants carried by the ...
Benjamin Podgursky, Maria Katz, Shenglai Li, Thomas Giardina, Becca Girod, Dhruva Chandramohan, Qinnan Zhang, Michael Feinman, Barry Behr, Jerry Lanchbury, Noor Siddiqui, Funda Suer, Yuntao Xia   +12 more
doaj   +1 more source

Long‐Read Sequencing of CAH and ADPKD Provides Novel Insights Into the Genetic Diagnosis of Male Infertility

Reproductive Medicine and Biology, Volume 25, Issue 1, January/December 2026.
ABSTRACT Purpose This study aimed to evaluate the utility of long‐read sequencing (LRS) in identifying variants of congenital adrenal hyperplasia (CAH) and autosomal dominant polycystic kidney disease (ADPKD) in infertile men, which may help further clarify genetic diagnosis and support genetic counseling and reproductive management. Methods A total of
Xiao Li, Chang Liu, Wen Liu, Xianlong Wang, Jiaolong Liu, Feifei Cai, Shaoming Lu   +6 more
wiley   +1 more source

Embryo response to aneuploidy through self-correction mechanism: a literature review

Middle East Fertility Society Journal
Background Meiotic and mitotic errors often lead to aneuploidy and mosaicism. In this context, the self-correction mechanism enables the embryo to preferentially retain and preserve euploid cells through processes such as apoptosis, necrosis, or ...
Achmad Kemal Harzif, Azizah Fitriayu Andyra, Atikah Sayogo, Nafi’atul Ummah, Aisyah Retno Puspawardani, Putri Nurbaeti, Budi Wiweko   +6 more
doaj   +1 more source