Results 41 to 50 of about 85,115,453 (207)

Preimplantation genetic testing legislation and accessibility in the Nordic countries [PDF]

, 2020
INTRODUCTION: Assisted reproduction technologies are being rapidly developed and implementation of preimplantation genetic testing (PGT) has allowed patients with genetic disorders to initiate pregnancies while minimizing or eliminating the risk of ...
Hydén-Granskog, Christel, Julius Hreinsson, Snorri Einarsson, Hreinsson, Julius, Hausken, Jon, Jon Hausken, Einarsson, Snorri, Lundin, Kersti, Ingerslev, Hans Jakob, Marie Louise Grøndahl, Iwarsson, Erik, Erik Iwarsson, Hans Jakob Ingerslev, Kersti Lundin, Christel Hydén‐Granskog, Grøndahl, Marie Louise, Lwarsson, E, Hyden-Granskog, C, Hreinsson, J, Einarsson, S, Grondahl, ML, Ingerslev, HJ, Lundin, K, Hausken, J   +23 more
core   +1 more source

Previously reported and here added cases demonstrate euploid pregnancies followed by PGT-A as “mosaic” as well as “aneuploid” designated embryos

Reproductive Biology and Endocrinology, 2023
Background After the longest time opposing all transfers of embryos by preimplantation genetic testing for aneuploidy (PGT-A) diagnosed as “chromosomal-abnormal,” the field has over recent years slowly been moving toward selective transfers of by PGT-A ...
Norbert Gleicher, Pasquale Patrizio, Lyka Mochizuki, David H. Barad   +3 more
doaj   +1 more source

Preimplantation genetic testing for aneuploidy (PGT-A)—finally revealed

Journal of Assisted Reproduction and Genetics, 2020
Natural fecundity of women decreases gradually and more rapidly after age 37 years. This decrease is accompanied by rising aneuploidy rates of pregnancies and can also be observed in products of conception of spontaneous abortions [1]. These observations lead to the hypothesis that transferring only euploid embryos in association with in vitro ...
Raoul, Orvieto, Norbert, Gleicher
openaire   +3 more sources

Indications for Preimplantation Genetic Testing for Aneuploidy (PGT-A).

, 2018
Indications for Preimplantation Genetic Testing for Aneuploidy (PGT-A).
Rupali Chopra (246435), Barbara Lawrenz (3990386), Human M. Fatemi (3990392), Alberto Liñán (5675405), Ana Arnanz (5675414), Asina Bayram (5675411), Ibrahim El Khatib (5675408), Carmen Rubio (500711)   +7 more
core   +1 more source

A ‘healthy baby’: The double imperative of preimplantation genetic diagnosis [PDF]

, 2010
This is the author's accepted manuscript. The final published article is available from the link below. Copyright @ 2010 The Authors.This article reports from a study exploring the social processes, meanings and institutions that frame and produce ...
Williams, C, Ehrich, K, Ehrich, Kathryn, Williams, Clare   +3 more
core   +1 more source

The inconsistency between two major aneuploidy-screening platforms—single-nucleotide polymorphism array and next-generation sequencing—in the detection of embryo mosaicism

BMC Genomics, 2022
Background In preimplantation genetic testing for aneuploidy (PGT-A), appropriate evaluation of mosaic embryos is important because of the adverse implications of transferring embryos with high-level mosaicism or discarding those with low-level mosaicism.
Dongjia Chen, Yan Xu, Chenhui Ding, Yali Wang, Yu Fu, Bing Cai, Jing Wang, Rong Li, Jing Guo, Jiafu Pan, Yanhong Zeng, Yiping Zhong, Xiaoting Shen, Canquan Zhou   +13 more
doaj   +1 more source

Preimplantation Genetic Testing for Monogenic Kidney Disease [PDF]

, 2020
Background and objectives: A genetic cause can be identified for an increasing number of pediatric and adult-onset kidney diseases. Preimplantation genetic testing (formerly known as preimplantation genetic diagnostics) is a reproductive technology that ...
Franka van Reekum, Paulussen, Aimee D. C., Stokman, Marijn F., Klaske D. Lichtenbelt, Jos C.M.F. Dreesen, Marijn F. Stokman, A. Titia Lely, Simcox, Cindy E, Nine V.A.M. Knoers, Knoers, Nine V A M, Lichtenbelt, Klaske D., Stokman, Marijn F, Cindy E. Simcox, van Tilborg, Theodora C., Simcox, Cindy E., Dreesen, Jos C. M. F., van Reekum, Franka, Lely, A. Titia, Lely, A Titia, Rozemarijn Snoek, van Eerde, Albertien M., Knoers, Nine V. A. M., Paulussen, Aimée D C, Aimée D.C. Paulussen, de Die-Smulders, Christine E. M., Snoek, Rozemarijn, Christine E.M. de Die-Smulders, Albertien M. van Eerde, van Tilborg, Theodora C, van Eerde, Albertien M, Lichtenbelt, Klaske D, Theodora C. van Tilborg, Dreesen, Jos C M F, de Die-Smulders, Christine E M, MS VPG/Gynaecologie, Genetica, Child Health, Genetica Klinische Genetica, MS Nefrologie, MS Verloskunde, Infection & Immunity, Circulatory Health, Cancer   +42 more
core   +1 more source

Cell-free DNA in spent culture medium effectively reflects the chromosomal status of embryos following culturing beyond implantation compared to trophectoderm biopsy.

PLoS ONE, 2021
This prospective study evaluated the accuracy of non-invasive preimplantation genetic testing for aneuploidy (niPGT-A) using cell-free DNA in spent culture medium, as well as that of preimplantation genetic testing for aneuploidy (PGT-A) using ...
Akihiro Shitara, Kazumasa Takahashi, Mayumi Goto, Harunori Takahashi, Takuya Iwasawa, Yohei Onodera, Kenichi Makino, Hiroshi Miura, Hiromitsu Shirasawa, Wataru Sato, Yukiyo Kumazawa, Yukihiro Terada   +11 more
doaj   +1 more source

Spectrum of Various Mosaicism Types According to Female Age: An Analysis of 36,506 Blastocysts Using Preimplantation Genetic Testing for Aneuploidy. [PDF]

Biomedicines
Background/Objectives: Mosaicism in preimplantation embryos has important implications for embryo selection and reproductive outcomes. This study investigates the age-related frequency of mosaicism, analyzes its subtypes, and evaluates its clinical ...
Jeon MS, Kim MJ, Choi N, Hong J, Choi R, Jeong Y, Lee HS, Lee KA, Yu EJ, Kang IS.   +9 more
europepmc   +2 more sources

A Spotlight on Yolk‐sac Tumors: Molecular Pathology, Current Diagnostics, and Novel Therapeutics

Andrology, EarlyView.
ABSTRACT Background Yolk‐sac tumors are an aggressive subtype of testicular cancer that significantly contribute to disease progression and therapy resistance, especially in adults. While testicular cancer generally has high cure rates with cisplatin‐based treatment, adult yolk‐sac tumors often appear as components of mixed tumors with poor response to
Evangelos Prokakis, Lisa Schneider, Felix Bremmer, Daniel Nettersheim   +3 more
wiley   +1 more source