Results 31 to 40 of about 85,115,453 (207)

Clinical application of sequencing-based methods for parallel preimplantation genetic testing for mitochondrial DNA disease and aneuploidy [PDF]

open access: yes, 2021
Since its first application in the 1990s, genetic testing of preimplantation embryos has undergone a major transformation and its utilisation continues to grow.
Joanna Poulton   +7 more
core   +1 more source

Debate 5: All Women with Recurrent Implantation Failure Should Be Offered PGT-A Motion For – Author: Tristan Hardy; Motion Against – Author: Richard Legro

open access: yesFertility & Reproduction, 2023
Motion: For Preimplantation genetic testing for aneuploidy (PGT-A) remains one of the most controversial aspects of reproductive medicine. The benefits of deselection of embryos using PGT-A must be considered according to the clinical situation. Although
Tristan Hardy, Richard Legro
doaj   +1 more source

The “mosaic” embryo: misconceptions and misinterpretations in preimplantation genetic testing for aneuploidy [PDF]

open access: yesFertility and Sterility, 2021
Preimplantation genetic testing for aneuploidy (PGT-A) remains one of the most controversial topics in reproductive medicine. With more than 40% of in vitro fertilization cycles in the United States reportedly involving PGT, both those in favor of and those opposed to PGT-A have significant interest in the efficacy of PGT-A. Ongoing issues include what
Nathan R, Treff, Diego, Marin
openaire   +2 more sources

Non-Invasive Preimplantation Genetic Testing for Aneuploidy and the Mystery of Genetic Material: A Review Article

open access: yes, 2022
This review focuses on recent findings in the preimplantation genetic testing (PGT) of embryos. Different preimplantation genetic tests are presented along with different genetic materials and their analysis.
Martin Stimpfel   +2 more
core   +1 more source

Preimplantation genetic testing for aneuploidy: The management of mosaic embryos

open access: yesClinical and Experimental Reproductive Medicine, 2022
As the resolution and accuracy of diagnostic techniques for preimplantation genetic testing for aneuploidy (PGT-A) are improving, more mosaic embryos are being identified. Several studies have provided evidence that mosaic embryos have reproductive potential for implantation and healthy live birth.
Eun Jeong Yu   +3 more
openaire   +2 more sources

Cost-effectiveness of preimplantation genetic testing for aneuploidy for fresh donor oocyte cycles

open access: yesF&S Reports, 2021
Objective: To determine whether in vitro fertilization (IVF) with preimplantation genetic testing for aneuploidy (PGT-A) is cost effective to achieve a live birth compared with IVF alone in fresh donor oocyte cycles.
Maria Facadio Antero, M.D.   +6 more
doaj   +1 more source

The association between sperm aneuploidy and male infertility: Screening, aetiology and possible routes to alternative therapy [PDF]

open access: yes, 2003
This thesis was submitted for the degree of Doctor of Philosophy and awarded by Brunel University.One in six couples wishing to start a family are infertile.
Tempest, Helen Ghislaine
core   +6 more sources

Healthy live births after mosaic blastocyst transfers with the use of next-generation sequencing

open access: yesTaiwanese Journal of Obstetrics & Gynecology, 2019
Objective: To determine whether transfer of high-mosaicism (≥50%) embryos can result in healthy newborns. Case report: Two embryos resulting from controlled ovarian stimulation (COS) in Patient one, 41 years of age (y/o), underwent preimplantation ...
Yung-Liang Liu   +5 more
doaj   +1 more source

Comparison of aneuploidy rates between conventional in vitro fertilization and intracytoplasmic sperm injection in in vitro fertilization–intracytoplasmic sperm injection split insemination cycles

open access: yesF&S Reports, 2020
Objective: To evaluate the influence of insemination methods on outcomes of preimplantation genetic testing for aneuploidy (PGT-A) by assessing PGT-A results in embryos that derived from conventional in vitro fertilization (IVF) versus intracytoplasmic ...
Jie Deng, M.D., Ph.D.   +4 more
doaj   +1 more source

Comparison of chromosomal status in reserved multiple displacement amplification products of embryos that resulted in miscarriages or live births: a blinded, nonselection case–control study

open access: yesBMC Medical Genomics, 2022
Objective To analyze chromosomal status in reserved multiple displacement amplification (MDA) products of embryos that result in miscarriages or live births.
Guoxia Yang   +6 more
doaj   +1 more source

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