Results 11 to 20 of about 85,115,453 (207)
Frontiers in Endocrinology, 2023 ObjectiveThe purpose of this study was to evaluate the influence of abnormal semen parameters on embryo aneuploidy based on single nucleotide polymorphism microarray (SNP array).MethodsA total of 464 blastocysts from 103 PGT-A cycles were analyzed.
Hongyi Yang +6 more
doaj +4 more sources
Advances in Preimplantation Genetic Testing for Monogenic Disease and Aneuploidy
Annual Review of Genomics and Human Genetics, 2017 Genetic testing of preimplantation embryos promises to prevent monogenic disease in children born to at-risk couples, the transfer of unbalanced embryos to patients carrying a balanced translocation, and the use of aneuploid embryos created during in vitro fertilization.
Nathan R, Treff, Rebekah S, Zimmerman
openaire +3 more sources
Taiwanese Journal of Obstetrics & Gynecology, 2019 Objective: The primary objective of this study was to investigate whether preimplantation genetic testing for aneuploidy (PGT-A) of blastocysts through array comparative genomic hybridization (aCGH) improves live birth rates (LBR) in IVF cycles for ...
Chun-I. Lee +6 more
doaj +2 more sources
Changes in sequencing technology used for preimplantation genetic testing for aneuploidy. [PDF]
J Assist Reprod GenetAbstract The continued development of assisted reproductive technologies has aimed to improve pregnancy outcomes through screening methods for the identification of embryos with monogenic disorders, chromosomal aneuploidy or structural abnormalities.
Oltramare VE, McDermott C, Dunn PJ.
europepmc +5 more sources
Next generation sequencing for preimplantation genetic testing of blastocysts aneuploidies in women of different ages [PDF]
Annals of Agricultural and Environmental Medicine, 2015 Most of the current preimplantation genetic screening of aneuploidies tests are based on the low quality and low density comparative genomic hybridization arrays. The results are based on fewer than 2,700 probes.
Krzysztof Lukaszuk +7 more
doaj +3 more sources
Reproductive and Developmental Medicine, 2019 Objective: To evaluate whether preimplantation genetic testing for aneuploidy (PGT-A) with comprehensive chromosome screening increases live birth rate (LBR) in normal karyotype couples with recurrent pregnancy loss (RPL). Methods: A retrospective cohort
Cai-Xia Lei +4 more
doaj +6 more sources
The Application of Clinical GeneticsYang Liu,1– 6,* Xiangxin Lan,1– 6,* Juanjuan Lu,1– 6,* Qian Zhang,1– 6 Tingting Zhou,1– 6 Tianxiang Ni,1– 6 Junhao Yan1– 6 1Center for Reproductive Medicine, Shandong University, Jinan, Shandong, 250012, People’s Republic of China; 2Key ...
Liu Y +6 more
doaj +1 more source
Single-cell sequencing shows mosaic aneuploidy in most human embryos
The Journal of Clinical InvestigationMammalian preimplantation embryos often contain chromosomal defects that arose in the first divisions after fertilization and affect a subpopulation of cells — an event known as mosaic aneuploidy. In this issue of the JCI, Chavli et al.
Sarah A. Robertson, Robert I. Richards
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Non-invasive preimplantation genetic testing for aneuploidies: an update [PDF]
Reproductive BioMedicine Online, 2022 Aneuploidy is common among preimplantation human embryos used in assisted reproductive technology. Because abnormal chromosome number can negatively affect reproductive outcome, in-vitro-fertilized embryos routinely undergo aneuploidy testing before transfer into the uterus.
Luis Navarro-Sánchez +3 more
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Noninvasive preimplantation genetic testing for aneuploidy
Bulletin of Russian State Medical University, 2023 To date the world community is actively working to optimize the approaches to determining chromosomal abnormalities in embryos. The study was aimed to assess the possibility of using noninvasive preimplantation genetic testing for aneuploidy (niPGT-A) through analysis of cell-free DNA in spent culture medium (SCM).
OI Lisitsyna +7 more
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