Results 21 to 30 of about 4,054 (204)

Noninvasive preimplantation genetic testing for aneuploidy using blastocyst spent culture medium may serve as a backup of trophectoderm biopsy in conventional preimplantation genetic testing [PDF]

BMC Medical Genomics
Background To investigate whether the noninvasive preimplantation genetic testing (niPGT) complement conventional preimplantation genetic testing (PGT) in the embryos for aneuploidy.
Songchang Chen, Li Wang, Yuting Hu, Yaxin Yao, Fangfang Gao, Chunxin Chang, Lanlan Zhang, Hefeng Huang, Daru Lu, Chenming Xu   +9 more
doaj   +2 more sources

Preimplantation genetic diagnosis

Zdravniški Vestnik, 2013
Backg round: Preimplantation genetic diagnosis (PGD) is used to analyze embryos before their transfer into uterus. It is suitable for a group of patients who are at a substantial risk of conceiving a pregnancy affected by a known genetic defect.
Karin Writzl
doaj   +1 more source

Pre-implantation Genetic Testing for Aneuploidy (PGT-A)

Thai Journal of Obstetrics and Gynaecology, 2020
Preimplantation genetic diagnosis (PGD) or embryo selection was first performed in 1989 using PCR for gender selection to avoid X-linked recessive disorder. However, there was a misdiagnosis due to allele drop out (ADO). Therefore, fluorescent in situ
Wirawit Piyamongkol
doaj   +1 more source

Evolution and utility of preimplantation genetic testing for monogenic disorders in assisted reproduction - A narrative review

Journal of Human Reproductive Sciences, 2021
Preimplantation genetic testing (PGT) for monogenic disorders and assisted reproductive technology have evolved and progressed in tandem. PGT started with single-cell polymerase chain reaction (PCR) followed by fluorescent in situ hybridisation for a ...
Firuza R Parikh, Arundhati S Athalye, Dhananjaya K Kulkarni, Rupesh R Sanap, Suresh B Dhumal, Dhanashree J Warang, Dattatray J Naik, Prochi F Madon   +7 more
doaj   +1 more source

Noninvasive preimplantation genetic testing for aneuploidy

Bulletin of Russian State Medical University, 2023
To date the world community is actively working to optimize the approaches to determining chromosomal abnormalities in embryos. The study was aimed to assess the possibility of using noninvasive preimplantation genetic testing for aneuploidy (niPGT-A) through analysis of cell-free DNA in spent culture medium (SCM).
OI Lisitsyna, AN Ekimov, EE Atapina, AG Syrkasheva, EG Goryainova, NP Makarova, DYu Trofimov, NV Dolgushina   +7 more
openaire   +1 more source

Molar pregnancy after in vitro fertilization with euploid single embryo transfer

F&S Reports, 2021
Objective: To describe a case of molar pregnancy after in vitro fertilization (IVF) resulting from the transfer of a euploid embryo derived from a monopronuclear zygote. Design: Case report and review of the literature.
Beth Zhou, M.D., Helen Paige Anglin, M.D., Alexander M. Quaas, M.D., Ph.D.   +2 more
doaj   +1 more source

Cost-effectiveness of preimplantation genetic testing for aneuploidies [PDF]

Fertility and Sterility, 2019
To evaluate the economical benefit of preimplantation genetic testing of aneuploidies (PGT-A) when applied in an extended culture and stringent elective single ET framework.Theoretical cost-effectiveness study.Not applicable.None.Comparison of the cost-effectiveness between two IVF treatment strategies: serial transfer of all available blastocysts ...
Edgardo Somigliana, Andrea Busnelli, Alessio Paffoni, Paola Vigano, Alessandra Riccaboni, Carmen Rubio, Antonio Capalbo   +6 more
openaire   +6 more sources

Introduction - Biopsy: A Major Factor that Can Impact the Clinical Outcome of PGTs

Fertility & Reproduction, 2023
Nowadays, blastocyst biopsy is widely used in preimplantation genetic tests (PGTs), especially in preimplantation genetic testing for aneuploidy (PGT-A).
Ling Chi
doaj   +1 more source

Navigating Non-invasive Preimplantation Genetic Testing for Aneuploidy (niPGT-A) – Technical Challenges and Ethical Considerations [PDF]

Journal of Human Reproductive Sciences
Alexis Heng Boon Chin, Ningyu Sun
doaj   +2 more sources

A systematic review of noninvasive preimplantation genetic testing for aneuploidy

Fertility and Sterility, 2023
Noninvasive and minimally invasive preimplantation genetic testing for aneuploidy (PGT-A) is a tool that may one day become the gold standard for embryonic chromosomal screening. Investigations on this topic have ranged from studying the culture media of embryos to the fluid inside the blastocoel, all in an attempt to find a reliable source of DNA ...
Cengiz, Cinnioglu, Heather, Glessner, Amy, Jordan, Sydney, Bunshaft   +3 more
openaire   +2 more sources