Results 61 to 70 of about 3,413 (174)

Deciphering mRNA Translation During Sperm Capacitation: A New Frontier in Fertility Research

Molecular Reproduction and Development, Volume 93, Issue 2, February 2026.
ABSTRACT Male infertility accounts for approximately 50% of infertility cases, with nearly 30% remaining unexplained after standard evaluations. This highlights the need for a better understanding of sperm function to advance diagnostic and therapeutic strategies. Sperm were long considered translationally quiescent; however, emerging evidence suggests
Saurabh Tiwari, Nehal Thakor, Jacob Thundathil   +2 more
wiley   +1 more source

Optimisation of Laser‐Assisted Biopsy Parameters in Bovine Embryos

Reproduction in Domestic Animals, Volume 61, Issue 2, February 2026.
ABSTRACT Although laser‐assisted biopsy has shown advantages in other species, optimised protocols for bovine embryos remain scarce. This study developed a systematically optimised laser biopsy method for bovine embryos, which demonstrated high post‐biopsy survival rates. Key parameters including laser energy, needle diameter, and operating medium were
Jingyu Zhang, Hang Shen, Zhenni Zhang, Jianhui Tian, Lei An, Yinjuan Wang   +5 more
wiley   +1 more source

Next generation sequencing for preimplantation genetic testing of blastocysts aneuploidies in women of different ages

Annals of Agricultural and Environmental Medicine, 2015
Most of the current preimplantation genetic screening of aneuploidies tests are based on the low quality and low density comparative genomic hybridization arrays. The results are based on fewer than 2,700 probes.
Krzysztof Lukaszuk, Grzegorz Jakiel, Waldemar Kuczynski, Sebastian Pukszta, Joanna Liss, Lukasz Plociennik, Aron Lukaszuk, Ewa Pastuszek   +7 more
doaj   +1 more source

Preimplantation Genetic Testing for Chromosomal Abnormalities: Aneuploidy, Mosaicism, and Structural Rearrangements [PDF]

Genes, 2020
There is a high incidence of chromosomal abnormalities in early human embryos, whether they are generated by natural conception or by assisted reproductive technologies (ART). Cells with chromosomal copy number deviations or chromosome structural rearrangements can compromise the viability of embryos; much of the naturally low human fecundity as well ...
openaire   +2 more sources

Incidence, Clinical Risk Factors, and Pregnancy Outcomes of Trophectoderm‐ and Inner Cell Mass–Poor‐Quality Blastocysts in Single Blastocyst Transfer Cycles: A Retrospective Cohort Study

Reproductive Medicine and Biology, Volume 25, Issue 1, January/December 2026.
ABSTRACT Purpose To study incidence, clinical risk factors, and pregnancy outcomes of trophectoderm‐ and inner cell mass–poor‐quality blastocysts in single blastocyst transfer cycles. Design A retrospective cohort study included patients who underwent their first single blastocyst transfer cycle.
Longbin Chen, Yangqin Peng, Shuoping Zhang, Yifan Gu, Fei Gong, Ge Lin, Lizhi Leng   +6 more
wiley   +1 more source

Assisted Reproductive Technology in Japan: A Summary Report for 2023 by the Committee on Professional Scientific Conduct and Clinical Ethics of the Japan Society of Obstetrics and Gynecology

Reproductive Medicine and Biology, Volume 25, Issue 1, January/December 2026.
In 2023, the second year of insurance coverage, the registry recorded the highest numbers of treatment cycles and newborns. Effective registry systems planned for 2026 will enable comprehensive evaluation of emerging trends in Japanese ART practice. ABSTRACT Purpose To summarize assisted reproductive technology (ART) data for 2023 collected through the
Yukiko Katagiri, Seung Chik Jwa, Akira Kuwahara, Takeshi Iwasa, Masanori Ono, Keiichi Kato, Hiroshi Kishi, Yoshimitsu Kuwabara, Fuminori Taniguchi, Miyuki Harada, Akira Iwase, Norihiro Sugino   +11 more
wiley   +1 more source

Expanding the horizons of embryo screening: performance and case studies of preimplantation genetic testing via whole genome sequencing

Academia Molecular Biology and Genomics
Conventional preimplantation genetic testing for aneuploidy (PGT-A) and for monogenic disorders (PGT-M) is very limited in scope. These methods typically assess chromosomal ploidy or target only one or two specific variants carried by the ...
Benjamin Podgursky, Maria Katz, Shenglai Li, Thomas Giardina, Becca Girod, Dhruva Chandramohan, Qinnan Zhang, Michael Feinman, Barry Behr, Jerry Lanchbury, Noor Siddiqui, Funda Suer, Yuntao Xia   +12 more
doaj   +1 more source

Successful Live Birth Following PGT‐SR in a Couple Who Were Both Carriers of Balanced Reciprocal Translocations Identified During Recurrent Pregnancy Loss Workup: A Case Report

Reproductive Medicine and Biology, Volume 25, Issue 1, January/December 2026.
ABSTRACT Case A non‐consanguineous couple with recurrent pregnancy loss was found to be carriers of two different balanced reciprocal translocations: 46,XX,t(13;16)(q14;q23) and 46,XY,t(4;12)(q21.1;q15). They underwent IVF with PGT‐SR, from which seven blastocysts were obtained.
Hiroaki Negishi, Daisuke Higeta, Satoh Maki, Setsuko Satoh, Youko Matsumiya, Nanami Takano, Hidemi Yokota, Mikako Yokota, Yoshimasa Yokota   +8 more
wiley   +1 more source

Embryo response to aneuploidy through self-correction mechanism: a literature review

Middle East Fertility Society Journal
Background Meiotic and mitotic errors often lead to aneuploidy and mosaicism. In this context, the self-correction mechanism enables the embryo to preferentially retain and preserve euploid cells through processes such as apoptosis, necrosis, or ...
Achmad Kemal Harzif, Azizah Fitriayu Andyra, Atikah Sayogo, Nafi’atul Ummah, Aisyah Retno Puspawardani, Putri Nurbaeti, Budi Wiweko   +6 more
doaj   +1 more source

From the Understanding of Maternal Molecules and Mechanisms to Predicting Embryonic Development

Reproductive Medicine and Biology, Volume 25, Issue 1, January/December 2026.
ABSTRACT Background Embryo quality is a critical determinant of successful outcomes in assisted reproductive technology (ART). Various molecular and cellular mechanisms in oocytes influence embryo quality, and their understanding can lead to the establishment of selection criteria for enhancing implantation rates. Methods This review summarizes current
Yubao Wei, Akihiro Inoue, Kei Miyamoto
wiley   +1 more source