Results 71 to 80 of about 3,413 (174)

Single-cell sequencing shows mosaic aneuploidy in most human embryos

The Journal of Clinical Investigation
Mammalian preimplantation embryos often contain chromosomal defects that arose in the first divisions after fertilization and affect a subpopulation of cells — an event known as mosaic aneuploidy. In this issue of the JCI, Chavli et al.
Sarah A. Robertson, Robert I. Richards
doaj   +1 more source

Preimplantation Genetic Screening in In Vitro Fertilization (IVF): A Comprehensive Review of Ethical, Clinical, and Technological Developments [PDF]

Journal of Medical and Life Science
Preimplantation Genetic Testing for Aneuploidy (PGT-A) and Preimplantation Genetic Screening (PGS) have become indispensable tools in In Vitro Fertilization (IVF) to increase pregnancy rates and enhance embryo choice.
Zina Al-Obaidi, Nabaa Al-Nawab, Mustafa Hadi, Ahmed Flayyih Hasan   +3 more
doaj   +1 more source

ChromInst: a multicentre evaluation of robustness in aneuploidy and structural rearrangement testing

Journal of Translational Medicine
Background Preimplantation genetic testing for aneuploidy and for chromosomal structural rearrangement (PGT-A/-SR) can improve clinical pregnancy rates and live birth rates, and shorten the time to pregnancy.
Wenbin Niu, Shanjun Dai, Linli Hu, Yao He, Xiqian Zhang, Xia Xue, Li Wu, Haixia Jin, Dun Liu, Keya Tong, Senlin Shi, Li Tian, Yifan Zhou, Guidong Yao, Sijia Lu, Yaxin Yao, Dunmei Zhao, Lei Jin, Haiyan Bai, Fenghua Liu, Dongyun Liu, Yingpu Sun   +21 more
doaj   +1 more source

Births from aneuploid embryos: where is the evidence?

BMJ Connections. Clinical Genetics and Genomics
Background Preimplantation genetic testing for aneuploidy (PGT-A) is used principally to identify embryos with whole chromosome aneuploidy, which are generally considered non-viable. Reports of healthy live births following transfer of embryos classified
Manuel Viotti, Andria Besser, Francesca Spinella, Christo G Zouves, Andrea R Victor, Mitko Madjunkov, Clifford Librach, Svetlana Madjunkova   +7 more
doaj   +1 more source

Issue Information

Acta Obstetricia et Gynecologica Scandinavica, Volume 105, Issue 4, Page 555-557, April 2026.
wiley   +1 more source

Preimplantation Genetic Testing for Aneuploidy Could Not Improve Cumulative Live Birth Rate Among 705 Couples with Unexplained Recurrent Implantation Failure

The Application of Clinical Genetics
Yang Liu,1– 6,* Xiangxin Lan,1– 6,* Juanjuan Lu,1– 6,* Qian Zhang,1– 6 Tingting Zhou,1– 6 Tianxiang Ni,1– 6 Junhao Yan1– 6 1Center for Reproductive Medicine, Shandong University, Jinan, Shandong, 250012, People’s Republic of China; 2Key ...
Liu Y, Lan X, Lu J, Zhang Q, Zhou T, Ni T, Yan J   +6 more
doaj  

Investigating developmental characteristics of biopsied blastocysts stratified by mitochondrial copy numbers using time-lapse monitoring

Reproductive Biology and Endocrinology
Background For in vitro fertilization (IVF), mitochondrial DNA (mtDNA) levels in the trophectodermal (TE) cells of biopsied blastocysts have been suggested to be associated with the cells’ developmental potential. However, scholars have reached differing
Chun-I Lee, Ching-Ya Su, Hsiu-Hui Chen, Chun-Chia Huang, En-Hui Cheng, Tsung-Hsien Lee, Pin-Yao Lin, Tzu-Ning Yu, Chung-I Chen, Ming-Jer Chen, Maw-Sheng Lee, Chien-Hong Chen   +11 more
doaj   +1 more source

Reply to Comment on “Clinical Significance of Biochemical Pregnancy Loss in Recurrent Pregnancy Loss Patients: Insights From Euploid Embryo Transfers Minimizing Embryonic Bias”

Reproductive Medicine and Biology
Background We appreciate the commentary by Satapathy, Mehta, and Sah on our study examining biochemical pregnancy loss (BPL) in recurrent pregnancy loss (RPL) following euploid embryo transfer.
Yoshimitsu Kuwabara
doaj   +1 more source

Preimplantation genetic diagnosis

Zdravniški Vestnik, 2013
Backg round: Preimplantation genetic diagnosis (PGD) is used to analyze embryos before their transfer into uterus. It is suitable for a group of patients who are at a substantial risk of conceiving a pregnancy affected by a known genetic defect.
Karin Writzl
doaj  

Predictive factors of aneuploidy in infertile patients undergoing IVF: a retrospective analysis in a private IVF practice

Middle East Fertility Society Journal
Background PGT-A has become an important part of IVF treatments. Despite its increased use, there are contradicting results on its role in improving reproductive outcomes of ART cycles.
Anastasia A. Salame, Elias M. Dahdouh, Rania Aljafari, David A. Samuel, Bhavya P. Koodathingal, Aparna Bajpai, Shabin Kainoth, Michael Fakih   +7 more
doaj   +1 more source