Results 71 to 80 of about 4,054 (204)
Expert Review of Molecular Diagnostics, 2016 Preimplantation genetic diagnosis (PGD) was introduced as an alternative to prenatal diagnosis: embryos cultured in vitro were analysed for a monogenic disease and only disease-free embryos were transferred to the mother, to avoid the termination of pregnancy with an affected foetus.
openaire +3 more sources
To test or not to test? A framework for counselling patients on preimplantation genetic testing for aneuploidy (PGT-A) [PDF]
Human Reproduction, 2018 What is the treatment path and cumulative live birth (CLB) rate from a single oocyte retrieval of patients who intend to pursue PGT-A at the start of an IVF cycle compared to matched controls?The choice of PGT-A at the start of the first IVF cycle decreases the CLB per oocyte retrieval for patients
Lauren A, Murphy +7 more
openaire +2 more sources
Virality versus veracity: A systematic review of TikTok information on prenatal aneuploidy testing
Pregnancy, Volume 2, Issue 3, May 2026.Abstract Objective Pregnant people are increasingly utilizing TikTok to understand medical information. However, the accuracy and reliability of this content remain largely unexamined. This study aimed to evaluate videos on prenatal aneuploidy testing by engagement, reliability, and quality, comparing results by content category and account type. Study
Ashley S. Houlihan +5 more
wiley +1 more source
Journal of Medical Case ReportsBackground Microdeletions and microduplications are chromosomal variants ranging up to 3 Mb in size. These abnormalities often arise spontaneously and have significant clinical implications, including developmental delay and congenital anomalies.
Maria Katz +8 more
doaj +1 more source
Journal of Genetic Counseling, Volume 35, Issue 2, April 2026.Abstract Prenatal Exome Sequencing (pES) increases the diagnostic rate for genetic disorders in pregnancies with structural abnormalities and substantially impacts parental decision‐making regarding pregnancy continuation or termination. Previous qualitative research on parental experiences of pES has typically been performed several months after ...
Maayke A. de Koning +6 more
wiley +1 more source
Molecular Genetics &Genomic Medicine, Volume 14, Issue 4, April 2026.Whole exome sequencing analysis on 55 couples and miscarriages from their current pregnancies reveals a significant heterogeneity and complexity in exomic variants contributing to RPL. ABSTRACT Background This study aimed to identify candidate genes for recurrent pregnancy loss (RPL).
Fanjuan Kong +4 more
wiley +1 more source
Telomere Length and Distribution in Three Developmental Stages [PDF]
, 2014 Telomeres are specialised nucleoprotein structures present at the ends of each chromatid that function to maintain genome stability. It is well established that a gradual decline in telomere length is associated with the process of cellular ageing, and ...
Digital Scientific, Turner, Kara Jane
core
Asian Journal of AndrologyIn this study, we aimed to investigate the influence of paternal oligozoospermia (OZ), asthenozoospermia (AZ), or teratozoospermia (TZ) on blastocyst ploidy and its potential interaction with maternal age. We analyzed 3383 embryos in 1091 preimplantation
Yang Zou +11 more
doaj +1 more source
Preimplantation genetic testing for aneuploidy: are we examining the correct outcomes?
, 2020 Questions continue to be raised regarding the benefit of genetic assessment of embryos prior to transfer in IVF, specifically with regards to preimplantation genetic testing for aneuploidy (PGT-A).
Kemper, J.M. +3 more
core +1 more source
Clinical Case Reports, Volume 14, Issue 3, March 2026.This integrated clinical approach optimizes the reproductive cycle in several steps, starting with nutrition (A): restricting carbohydrates and inducing ketosis to reduce inflammation and improve insulin sensitivity, which benefits follicular development.
Tania G. Rojas‐Pérez +7 more
wiley +1 more source