Results 91 to 100 of about 85,115,453 (207)

Predicting live birth following single euploid frozen‐embryo transfer via β‐hCG dynamics: iHOPE prognostic model with external validation

Ultrasound in Obstetrics &Gynecology, Volume 67, Issue 6, Page 824-835, June 2026.
ABSTRACT Objectives To determine the prognostic value of serum β‐human chorionic gonadotropin (β‐hCG) for predicting live birth following single euploid frozen‐embryo transfer (FET), and to develop and validate a prognostic model (iHOPE) for this purpose. Methods This retrospective cohort study used data from two large fertility practices.
E. Kalafat, B. Ata, R. Del Gallego, A. Freedman, L. R. Hoyos, I. Elkhatib, K. A. Miller, H. Fatemi, B. Lawrenz   +8 more
wiley   +1 more source

Telomere Length and Distribution in Three Developmental Stages [PDF]

, 2014
Telomeres are specialised nucleoprotein structures present at the ends of each chromatid that function to maintain genome stability. It is well established that a gradual decline in telomere length is associated with the process of cellular ageing, and ...
Digital Scientific, Turner, Kara Jane
core  

Embryo response to aneuploidy through self-correction mechanism: a literature review

Middle East Fertility Society Journal
Background Meiotic and mitotic errors often lead to aneuploidy and mosaicism. In this context, the self-correction mechanism enables the embryo to preferentially retain and preserve euploid cells through processes such as apoptosis, necrosis, or ...
Achmad Kemal Harzif, Azizah Fitriayu Andyra, Atikah Sayogo, Nafi’atul Ummah, Aisyah Retno Puspawardani, Putri Nurbaeti, Budi Wiweko   +6 more
doaj   +1 more source

Expanding the horizons of embryo screening: performance and case studies of preimplantation genetic testing via whole genome sequencing

Academia Molecular Biology and Genomics
Conventional preimplantation genetic testing for aneuploidy (PGT-A) and for monogenic disorders (PGT-M) is very limited in scope. These methods typically assess chromosomal ploidy or target only one or two specific variants carried by the ...
Benjamin Podgursky, Maria Katz, Shenglai Li, Thomas Giardina, Becca Girod, Dhruva Chandramohan, Qinnan Zhang, Michael Feinman, Barry Behr, Jerry Lanchbury, Noor Siddiqui, Funda Suer, Yuntao Xia   +12 more
doaj   +1 more source

A systematic review and meta-analysis of the diagnostic accuracy after preimplantation genetic testing for aneuploidy. [PDF]

PLoS One
OBJECTIVE: Aneuploidy accounts for many pregnancy failures and congenital anomalies. Preimplantation genetic testing for aneuploidy (PGT-A) is a screening test applied to embryos created from in vitro fertilization to diminish the chance of an aneuploid ...
Bacal V, Li A, Shapiro H, Rana U, Zwingerman R, Avery L, Palermo A, Philipoppolous E, Chan C.   +8 more
europepmc   +2 more sources

Second-generation preimplantation genetic testing for aneuploidy in assisted reproduction: a SWOT analysis

Second-generation preimplantation genetic testing for aneuploidy (PGT-A 2.0) in patients with an unfavourable reproductive and IVF prognosis is becoming common practice, with the aim of improving reproductive outcomes.
Bosch Aparicio, Ernesto, Checa Vizcaíno, Miguel Ángel, Llácer, Joaquín, Fontes Jiménez, Juan, García Velasco, Juan Antonio, Bellver Pradas, José, Fábregues, Francisco, Requena, Antonio, Espinós Gómez, J. J.   +8 more
core   +1 more source

ChromInst: a multicentre evaluation of robustness in aneuploidy and structural rearrangement testing

Journal of Translational Medicine
Background Preimplantation genetic testing for aneuploidy and for chromosomal structural rearrangement (PGT-A/-SR) can improve clinical pregnancy rates and live birth rates, and shorten the time to pregnancy.
Wenbin Niu, Shanjun Dai, Linli Hu, Yao He, Xiqian Zhang, Xia Xue, Li Wu, Haixia Jin, Dun Liu, Keya Tong, Senlin Shi, Li Tian, Yifan Zhou, Guidong Yao, Sijia Lu, Yaxin Yao, Dunmei Zhao, Lei Jin, Haiyan Bai, Fenghua Liu, Dongyun Liu, Yingpu Sun   +21 more
doaj   +1 more source

Preimplantation Genetic Screening in In Vitro Fertilization (IVF): A Comprehensive Review of Ethical, Clinical, and Technological Developments [PDF]

Journal of Medical and Life Science
Preimplantation Genetic Testing for Aneuploidy (PGT-A) and Preimplantation Genetic Screening (PGS) have become indispensable tools in In Vitro Fertilization (IVF) to increase pregnancy rates and enhance embryo choice.
Zina Al-Obaidi, Nabaa Al-Nawab, Mustafa Hadi, Ahmed Flayyih Hasan   +3 more
doaj   +1 more source

Abstracts

Molecular Oncology, Volume 20, Issue S1, Page 1-692, August 2026.
Abstracts submitted to the ‘EACR 2026 Congress: Innovative Cancer Science’, from 08–11 June 2026 and accepted by the Congress Organising Committee are published in this Supplement of Molecular Oncology, an affiliated journal of the European Association for Cancer Research (EACR).
wiley   +1 more source

Non-Invasive Preimplantation Genetic Testing

To minimise the influence of chromosomal abnormalities during IVF treatment, embryos can be screened before transfer using preimplantation genetic testing.
Carmen Rubio, Luis Navarro-Sánchez, Daniela N. Bakalova   +2 more
core   +1 more source