Cell Receptor and Cofactor Interactions of the Contact Activation System and Factor XI
Frontiers in Medicine, 2018 The contact activation system (CAS) or contact pathway is central to the crosstalk between coagulation and inflammation and contributes to diverse disorders affecting the cardiovascular system. CAS initiation contributes to thrombosis but is not required
Monika Pathak +3 more
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Hereditary angioedema (HAE) in children and adolescents : a consensus on therapeutic strategies [PDF]
, 2012 Hereditary angioedema due to C1 inhibitor (C1 esterase inhibitor) deficiency (types I and II HAE-C1-INH) is a rare disease that usually presents during childhood or adolescence with intermittent episodes of potentially life-threatening angioedema ...
Aberer, Werner +11 more
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Eluate derived by extracorporal antibody-based immunoadsorption elevates the cytosolic Ca2+ concentration in podocytes via B-2 kinin receptors [PDF]
, 2002 Background/Aim: Patients with idiopathic focal segmental glomerulosclerosis (FSGS) often develop a recurrence of the disease after kidney transplantation.
Fink, E. +6 more
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Mechanisms and regulation of the polyphosphate/factor XII-driven contact system in thrombosis and hemostasis [PDF]
, 2016 Blood coagulation leading to fibrin formation is essential to prevent loss of blood (hemostasis), but can also contribute to occlusion of vessels (thrombosis).
Labberton, Linda
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A chromatographic method for the production of a human immunoglobulin G solution for intravenous use
Brazilian Journal of Medical and Biological Research, 1998 Immunoglobulin G (IgG) of excellent quality for intravenous use was obtained from the cryosupernatant of human plasma by a chromatographic method based on a mixture of ion-exchange, DEAE-Sepharose FF and arginine Sepharose 4B affinity chromatography and ...
K. Tanaka +7 more
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Glycosaminoglycans affect the interaction of human plasma kallikrein with plasminogen, factor XII and inhibitors [PDF]
, 2003 Human plasma kallikrein, a serine proteinase, plays a key role in intrinsic blood clotting, in the kallikrein-kinin system, and in fibrinolysis. The proteolytic enzymes involved in these processes are usually controlled by specific inhibitors and may be ...
Araujo, Mariana da Silva +7 more
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Revista do Instituto de Medicina Tropical de São Paulo, 1984 No plasma de 20 doentes portadores da forma hepatesplênica da esquistossomose mansônica, assim como no de 18 indivíduos normais, foram avaliados pré-albumina, precalicreína (atividade amidolítica) e protrombina-antígeno.
Nora Manoukian, Durval R. Borges
doaj
Processing of Factor XII during Inflammatory Reactions
Frontiers in Medicine, 2016 The contact system was originally identified as an obsolete part of the coagulation system, but it has been repeatedly implicated in inflammatory states, such as infection, as well as in allergic- and chronic inflammatory disease. Under these conditions,
Bernard Nico Jukema +2 more
doaj +1 more source
The effects of arterial flow on platelet activation, thrombus growth, and stabilization [PDF]
, 2017 Injury of an arterial vessel wall acutely triggers a multifaceted process of thrombus formation, which is dictated by the high-shear flow conditions in the artery. In this overview, we describe how the classical concept of arterial thrombus formation and
Angelillo-Scherrer, Anne +3 more
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Factor VIII deficiency inhibition or abnormal contact [PDF]
, 2015 Poster presented at the International Society on Thrombosis and Haemostasis 2015 Congress, 20-25 June 2015 ...
Azevedo, Ana Paula +2 more
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