Results 131 to 140 of about 13,204 (244)
The influence of environmental factors on premature ovarian insufficiency and ovarian aging
Premature ovarian insufficiency and ovarian aging are complex conditions that affect women's reproductive health and overall well-being. They are both characterized by hypergonadotropic hypogonadism and infertility, and together affect about 1 in ...
Evangelinakis, Nikolaos +6 more
core
Communications BiologyPremature ovarian insufficiency (POI) and age-related natural-aging ovarian insufficiency (ARNA-OI) pose pressing global health challenges, necessitating effective therapeutic strategies and a deep understanding of their underlying mechanisms. This study
Jiajia Sun +10 more
doaj +1 more source
Lifestyle Management in Menopause: A Systematic Review of Women With Premature Ovarian Insufficiency
Clinical Endocrinology, EarlyView.ABSTRACT Objective Premature ovarian insufficiency (POI), the loss of ovarian function before age 40, increases the risk of cardiovascular disease, low bone mineral density, dementia and psychological distress. Lifestyle interventions reduce chronic disease risk in other populations and, with hormone therapy, may improve health outcomes in POI.
Ladan Yeganeh +4 more
wiley +1 more source
BJOG: An International Journal of Obstetrics &Gynaecology, EarlyView.
Ursula Blyth +9 more
wiley +1 more source
Obesity in Classic Congenital Adrenal Hyperplasia: Mechanisms, Complications and Management
Clinical Endocrinology, EarlyView.ABSTRACT Classic congenital adrenal hyperplasia (CCAH) is an autosomal recessive genetic disorder primarily caused by 21‐hydroxylase deficiency. Although the survival rate of patients has significantly improved with glucocorticoid replacement therapy, long‐term use of supraphysiological doses and multiple factors inherent to the disease itself have led
Jialin Mu +5 more
wiley +1 more source
Premature Ovarian Insufficiency: Procreative Management and Preventive Strategies
, 2018 Premature ovarian insufficiency (POI) is the loss of normal hormonal and reproductive function of ovaries in women before age 40 as the result of premature depletion of oocytes.
Chae-Kim, Jennifer J. +4 more
core +1 more source
ADAM17 and its proteolytic targets in disease pathogenesis
The FEBS Journal, EarlyView.ADAM17 as a multifunctional sheddase with contrasting roles across inflammatory, metabolic, cardiovascular, and neoplastic diseases. Through regulated activation by iRhom, iTAP/FRMD8, and tetraspanins, ADAM17 cleaves diverse membrane ligands and receptors, thereby promoting inflammation, fibrosis, obesity, insulin resistance, and tumor progression ...
Abdulbasit Amin, Marina Badenes
wiley +1 more source
Dialysis and Pregnancy: Optimizing Therapy for Best Maternal and Fetal Outcomes
Hemodialysis International, EarlyView.ABSTRACT Pregnancy in women with end‐stage kidney disease (ESKD) requiring dialysis remains high risk, with significant maternal and fetal complications. While fertility rates are markedly reduced in this population, advances in dialysis care and obstetric management have led to increasing reports of successful pregnancies.
Shreepriya Mangalgi, Silvi Shah
wiley +1 more source
The supplemental material of the paper entitled "Variants in Homologous Recombination Genes EXO1 and RAD51 Related with Premature Ovarian Insufficiency"
Liangran Zhang +9 more
core +1 more source
Hepatology Research, EarlyView.ABSTRACT Aim Steatotic liver disease (SLD), including metabolic dysfunction–associated SLD (MASLD) and metabolic dysfunction–associated alcohol‐related liver disease (MetALD), is a growing global health burden. Although impaired mastication is linked to metabolic disorders, its role in SLD remains unclear.
Takashi Miyano +4 more
wiley +1 more source