Results 121 to 130 of about 516,689 (292)

Incidence and etiologic factors of premature ovarian insufficiency : register-based nationwide study [PDF]

Premature ovarian insufficiency (POI) is defined as the loss of ovarian function before the age of 40. According to the literature, POI affects approximately 1% of women globally.
Silvén, Heidi
core   +1 more source

Inducers and Inhibitors of Pyroptotic Death of Granulosa Cells in Models of Premature Ovarian Insufficiency and Polycystic Ovary Syndrome

Reproductive Sciences
Granulosa cells (GCs), the largest cell population and primary source of steroid hormones in the ovary, are the important somatic ovarian components.
Çağlar Berkel
semanticscholar   +1 more source

Peptide‐directed nanovehicles enabling tumor‐selective ROS amplification and antitumor immunity

VIEW, EarlyView.
Cancer cells are vulnerable to oxidative stress, yet exploit immune tolerance to escape destruction. In contrast, their metabolic profile is markedly altered to support rapid proliferation, accompanied by elevated production of reactive oxygen species (ROS).
Manuela Calin, Galyna Bila, Ileana Manduteanu, Rostyslav Bilyy   +3 more
wiley   +1 more source

Premature ovarian insufficiency: a toolkit for the primary care physician

, 2021
Premature ovarian insufficiency (POI) refers to the loss of ovarian activity before the age of 40 years, which leads to hypoestrogenism and amenorrhea.
Kalantaridou, S., Paschou, S.A., Lambrinoudaki, I., Makrakis, E., Panay, N., Faubion, S., Lumsden, M.A.   +6 more
core   +1 more source

Current Status and Future Prospects of Stem Cell Therapy for Infertile Patients with Premature Ovarian Insufficiency

Biomolecules
Premature ovarian insufficiency (POI), also known as premature menopause or premature ovarian failure, signifies the partial or complete loss of ovarian endocrine function and fertility before 40 years of age.
Hye Kyeong Kim, Tae Jin Kim
semanticscholar   +1 more source

Risk of Cancer With Hormone Replacement Therapy: A Narrative Review

BJOG: An International Journal of Obstetrics &Gynaecology, EarlyView.
ABSTRACT Hormone replacement therapy (HRT) remains the cornerstone of menopausal symptom management, effectively alleviating vasomotor symptoms and genitourinary syndrome, whilst mitigating long‐term risks such as osteoporosis. However, despite an increasing body of evidence on the relative safety of HRT, earlier studies that demonstrated an increased ...
Gabriella Yongue, Zachary Nash, Vikram Talaulikar, Shibani Nicum   +3 more
wiley   +1 more source

A 14-year-old girl with premature ovarian insufficiency but with a positive pregnancy test [PDF]

Objectives: Childhood cancer survivors are at risk for premature ovarian insufficiency, especially after treatment with alkylating agents. The objective of this report is to highlight a case in which this phenomenon caused a false-positive pregnancy test.
Touwslager, Robbert N.H., Zwaan, C. Michel, Bakker, Boudewijn, Lentjes, Eef G.W.M., Looijenga, Leendert H.J., Van Santen, Hanneke M.   +5 more
core   +3 more sources

Intraovarian injection of securinine stimulates the growth of small ovarian follicles by reducing stromal suppression

Nature Communications
The lack of hormone-responsive follicles is a major challenge in treating infertility/subfertility in women with premature ovarian insufficiency or diminished ovarian reserve.
Yu Zhao, Dongteng Liu, Zexiong Lin, Shuzi Deng, Xudong Zhao, Yiting Sun, Yihui Zhang, Qiong Zhang, Jingkai Gu, Yuan Xiao, Tianren Wang, Haonan Lu, Jing Zhao, Karen K. L. Chan, Yu Li, William S. B. Yeung, Kui Liu   +16 more
doaj   +1 more source

Bone health in women with premature ovarian insufficiency/early menopause: a 23-year longitudinal analysis

Human Reproduction
STUDY QUESTION What is the frequency of, and predictors for, osteoporosis, fractures, and osteoporosis management (investigation, treatment) in women with premature ovarian insufficiency (POI; menopause
A. Jones, J. Enticott, P. Ebeling, G. Mishra, H. Teede, A. Vincent   +5 more
semanticscholar   +1 more source

Reproductive Challenges of the Ageing Female: A Comprehensive Narrative Review

BJOG: An International Journal of Obstetrics &Gynaecology, EarlyView.
ABSTRACT Changes in societal norms over the last few decades have resulted in novel family planning trends, notably delayed childbearing and increased maternal age at the birth of the first child. Despite advances in reproductive medicine, ageing poses significant challenges.
Sofia Bitzika, Meletios P. Nigdelis, Angelos Daniilidis, Erich‐Franz Solomayer, Irene Lambrinoudaki, Efstratios M. Kolibianakis, Dimitrios G. Goulis   +6 more
wiley   +1 more source