Results 101 to 110 of about 516,689 (292)

Hormone replacement in premature ovarian insufficiency [PDF]

Premature ovarian insufficiency (POI) is defined as loss of ovarian function in women less-than 40 years. This review summarises the causes and the possible treatment options. POI can be idiopathic, caused by genetic, autoimmune, or metabolic disease, or
Thomsen, Cæcilie Weber, Gislinge, Julie Isabelle Plougmann, Ravn, Pernille; id_orcid   +2 more
core   +4 more sources

Supplemental information from: "Homozygous variant in KASH5 causes premature ovarian insufficiency by disordered meiotic homologous pairing"

, 2022
Supplemental information from: "Homozygous variant in KASH5 causes premature ovarian insufficiency by disordered meiotic homologous pairing"
Qian Zhang (12777767)
core   +1 more source

The new WHO infertility guideline: A universal right to equitable, evidence‐based fertility care

International Journal of Gynecology &Obstetrics, EarlyView.
Abstract The WHO ‘Guideline for the prevention, diagnosis and treatment of infertility’ heralds a significant global shift towards recognizing infertility as a medical condition requiring prevention, diagnosis, treatment and policy support. This recognition is vital for the one in six people with infertility worldwide and for policymakers trying to ...
M. Louise Hull, Kurt T. Barnhart, Nikhil C. Purandare, Aparna Sridhar, E. Göknur Topçu, Scott M. Nelson, on behalf of the FIGO REI committee, M. Louise Hull, Nikhil Purandare, Elif G. Topcu, Jackline Akol, Akira Iwase, Ivonne Diaz Yamal, Haroon Latif, Pablo Diaz Spíndola, Sunita R. Tandulwadkar, Virginia Chaquiriand, Ying Cheong, Scott Nelson, Kurt Barnhart   +19 more
wiley   +1 more source

Changing Etiological Spectrum of Premature Ovarian Insufficiency over the Past Decades: A Comparative Analysis of Two Cohorts from a Single Center

Diagnostics
Background: Premature ovarian insufficiency (POI) is a complex and heterogeneous condition affecting women of reproductive age. Historically, most POI cases have been classified as idiopathic due to limited diagnostic capabilities.
Szilvia Csehely, Adrienn Kun, Edina Orbán, Tamás Katona, Mónika Orosz, Zoárd Tibor Krasznai, Tamás Deli, Attila Jakab   +7 more
doaj   +1 more source

Mechanisms and treatment modalities related to premature ovarian insufficiency in mitochondria: literature review

Journal of Ovarian Research
Premature ovarian insufficiency (POI) is a common, heterogeneous disorder that affects up to 3.5% of women under 40 years of age and is defined by oligo/amenorrhoea, hypo-oestrogenism, and markedly elevated gonadotrophin levels.
Hui-Hui Li, Xin-Yu Zhu, Ruo-Tong Ju, Pu-Hua Zhang, Tingting Xue, Shu Wang, Rui-Xiang Zhu, Jia-Li Luo, Xuan Jing, Xiang-Rong Cui   +9 more
semanticscholar   +1 more source

Human biomarker navigator

iMeta, EarlyView.
The Human Biomarker Navigator integrates the disease continuum, biomarker dynamics, cross‐organ biomarker networks, biomarker classification, and technology‐driven paradigms. It maps how biomarkers link multi‐system physiology and pathology across the nervous, respiratory, endocrine, circulatory, immune, digestive, urinary, reproductive, and ...
Meng‐Yao Li, Qian Zhang, Zijie Wang, Zeping Gui, Jing Liu, Jingda Li, Maojun Jiang, Zukang Chang, Qingqing Han, Bendong Yang, Tariq Saeed, Jun Li, Jinghan Jia, Chenghu Song, Tong Shao, Tianhuan Peng, Xueying Zhang, Pingping Guo, Jun Luo, Gangao Yang, Yuan Wan, Gokhan Zengin, Quan Yuan, Lingru Li, Xiaohui Fan, Yang Luo, Lvyun Zhu, Yanfei Zheng, Wenjun Mao, Wenlong Sun   +29 more
wiley   +1 more source

Out of synchrony with the imagined self: A scoping review of self-concept in premature ovarian insufficiency and early menopause. [PDF]

Br J Health Psychol
Abstract Objective Premature ovarian insufficiency (POI) and early menopause (EM) can have life‐altering physical and psychological impacts, with potential consequences for an individual's sense of self. However, understanding of these potential consequences is limited, with much of the literature generalizing such experiences from naturally occurring ...
Seberry LM, Evans S, Mikocka-Walus A, Van Niekerk LM.   +3 more
europepmc   +2 more sources

Epilepsy surgery through a reproductive lifespan lens

Epilepsia, EarlyView.
Aisha A. Abdulrazaq, Dorothee Kasteleijn‐Nolst Trenite, Torbjörn Tomson   +2 more
wiley   +1 more source

Multi‐omics–driven precision medicine

iMeta, EarlyView.
Multi‐omics‐driven precision medicine (MODPM) provides a multiscale, continuously learnable framework that integrates genomics, epigenomics, transcriptomics, proteomics, metabolomics, microbiome profiles, and clinical data. Powered by artificial intelligence and foundation models, MODPM enables cross‐modal representation learning, contextual modeling ...
Huibo Li, Zhe Zhao, Yifan Zhang, Yao Ma, Gaofei Hu, Min Zeng, Zhanqun Yang, Zixuan Zhao, Xin Zhou, Wei Hu, Yuxuan Sun, Meng Su, Jun Li, Matthew Whiteman, Wei Fu, Chao Zhong, Lemin Zheng, Long Chen, Hairong Lv, Rongsheng Zhao, Yi Zhun Zhu   +20 more
wiley   +1 more source

The overlooked and undertreated perils of premature ovarian insufficiency

Cleveland Clinic journal of medicine
Premature ovarian insufficiency (POI) is loss of ovarian function before age 40. Genetic, autoimmune, and iatrogenic causes are well defined, but 90% of cases are idiopathic.
Samantha F. Butts
semanticscholar   +1 more source