Results 81 to 90 of about 13,204 (244)

Factors influencing premature ovarian insufficiency: a systematic review and meta-analysis

Journal of Obstetrics and Gynaecology
Background Premature ovarian insufficiency (POI) has multiple contributing factors. This study aims to systematically evaluate these factors and their mechanisms, identify high-risk groups, support early intervention, and provide a basis for future ...
Shuling Lin, Shanyan Chen, Qin Zhang
doaj   +1 more source

Use of Machine Learning to Identify Markers of Risk for Fragile X‐Associated Tremor/Ataxia Syndrome: A Preliminary Analysis

Annals of Neurology, EarlyView.
Objective The objective of this study was to examine whether machine learning has the capacity to prospectively identify and predict the emergence of Fragile X‐associated tremor/ataxia syndrome (FXTAS) among male fragile X premutation carriers (PCs). Methods We explored neuropsychological and motor evaluation metrics, brain magnetic resonance imaging ...
Chitrabhanu Gupta, Angeela Poudel, Jun Yi Wang, Randi Hagerman, Glenda Espinal, Jessica Famula, Andrea Schneider, Flora Tassone, Susan M. Rivera, Chen‐Nee Chuah, David Hessl   +10 more
wiley   +1 more source

Therapeutic Applications of Stimuli‐Based Release and Engineering of Extracellular Vesicles

Advanced NanoBiomed Research, EarlyView.
This review summarizes the effects of endogenous and exogenous stimuli, their effects on the natural release of extracellular vesicles, as well as their uptake and release. It also gives an overview of stimuli‐responsive EVs and their therapeutic applications. Extracellular vesicles (EVs), nano‐ to microsized lipid bilayer membrane‐bound particles, are
Gloria Kemunto, Kristen Dellinger
wiley   +1 more source

Evaluation of Neutrophil–Lymphocyte Ratio, Platelet–Lymphocyte Ratio and Red Blood Cell Distribution Width–Platelet Ratio for Diagnosis of Premature Ovarian Insufficiency

Journal of Family and Reproductive Health, 2017
Objective: To evaluate whether systemic inflammatory markers (neutrophil to lymphocyte ratio (NLR), platelet to lymphocyte ratio (PLR) and red blood cell distribution width (RDW) to platelet ratio (RPR)) can be used as reliable markers for the diagnosis ...
Gülşah Ilhan, Fatma Ferda Verit Atmaca, Esra Altan, Ali Galip Zebitay, Hamdullah Sozen, Hurkan Akyol, Meryem Kurek Eken   +6 more
doaj  

Premature Ovarian Insufficiency - an update on recent advances in understanding and management [version 1; referees: 3 approved]

F1000Research, 2017
Premature ovarian insufficiency is a complex and relatively poorly understood entity with a myriad of etiologies and multisystem sequelae that stem from premature deprivation of ovarian sex hormones.
Saioa Torrealday, Pinar Kodaman, Lubna Pal   +2 more
doaj   +1 more source

Tackling cancer stemness with nanotechnology in the era of precision medicine

BMEMat, EarlyView.
Precise customization of nanoparticles (NPs) enables active targeting of cancer stem cells (CSCs), thereby improving drug delivery and therapeutic efficacy. NP‐based probing enhances CSC detection through imaging and liquid biopsy, whereas diverse therapeutic payloads improve therapeutic outcomes.
Shaolei Guo, Shun Yao, Lihui Meng, Chunyuan Chen, Yuechu Lucinda Lu, Rong Lu, Kashif Rafiq Zahid, Umar Raza, Qingzhi Wu, Wenli Chen   +9 more
wiley   +1 more source

Premature ovarian insufficiency – to treat or not to treat?

Reproductive Endocrinology, 2019
Premature ovarian insufficiency (POI) is a rare but very damaging lifestyle condition that occurs at 1–1.5 of women and means termination of menstrual function up to 40 years old. POI impact on women’s wellbeing includes lipid metabolism dysregulation, haemostasis regulation changes, both leading to heart diseases risk increasing, psychological ...
O. S. Zahorodnia, I. B. Ventskivska, A. V. Kazak   +2 more
openaire   +5 more sources

Hormone replacement in premature ovarian insufficiency [PDF]

Premature ovarian insufficiency (POI) is defined as loss of ovarian function in women less-than 40 years. This review summarises the causes and the possible treatment options. POI can be idiopathic, caused by genetic, autoimmune, or metabolic disease, or
Thomsen, Cæcilie Weber, Gislinge, Julie Isabelle Plougmann, Ravn, Pernille; id_orcid   +2 more
core   +2 more sources

Effectiveness of Instructional Guidelines on Awareness and Perception of Premature Ovarian Insufficiency Women regarding Stem Cell- Based Ovarian Regeneration [PDF]

Egyptian Journal of Health Care
Background: Globally, reproductive aging is increasing and is inextricably linked to aging in general. Premature ovarian insufficiency (POI), which has primarily had an idiopathic etiology up to this point, is an extreme manifestation of reproductive ...
Doaa Lotfi Afifi Alqersh, Hanan E. Nada
doaj   +1 more source

Women with epilepsy: Evidence‐based counseling across the lifespan

Epilepsia, EarlyView.
Abstract Women with epilepsy (WWE) encounter distinct and evolving challenges across the lifespan that require clinical management extending beyond seizure control alone. Although awareness of sex‐specific aspects of epilepsy has increased, important gaps remain in their integration into routine care.
Barbara Tettenborn, Georgia Ramantani, Dominique Flügel, Verena Gaus, Susanne Schubert‐Bast, Elisabeth Sellitto, Jennifer Bausch, Bettina Schmitz   +7 more
wiley   +1 more source