Results 81 to 90 of about 516,689 (292)
BMEMat, EarlyView.Engineered bacteria serve as smart, living therapeutics that target tumors, deliver drugs, and remodel immunosuppressive microenvironments. This review highlights their potential to potentiate immunotherapy, radiotherapy, and chemotherapy, offering a promising paradigm for precise and synergistic cancer treatment. Abstract The dynamic interplay between
Haonan Shen +9 more
wiley +1 more source
Plasma metabolomic characterization of premature ovarian insufficiency
Journal of Ovarian Research, 2023 Background Premature ovarian insufficiency (POI) patients are predisposed to metabolic disturbances, including in lipid metabolism and glucose metabolism, and metabolic disorders appear to be a prerequisite of the typical long-term complications of POI ...
Xing-Yu Zhou +10 more
doaj +1 more source
ClimactericObjective Premature ovarian insufficiency (POI) is associated with reduced quality of life and increased health risks. While hormone therapy (HT) is standard treatment, some women seek other options to treat its sequelae. This review explores the role of
Alison Maunder +4 more
semanticscholar +1 more source
Gapo Syndrome: A New Syndromic Cause Of Premature Ovarian Insufficiency
, 2017 Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)Premature ovarian insufficiency has the following causes: genetic, autoimmune, metabolic, infectious, and iatrogenic dysfunctions (including radiotherapy, chemotherapy and surgery).
C. L.; Ferreira +5 more
core +1 more source
, 2021 Purpose It is still not clear whether to screen women with primary premature ovarian insufficiency for autoimmunity. Moreover, a possible association of autoimmunity with decreased bone mass density in premature ovarian insufficiency patients has not ...
Beitl, Klara +7 more
core +1 more source
International Journal of Gynecology &Obstetrics, Volume 169, Issue 1, Page 112-120, April 2025.Abstract Objective In the present study, a bidirectional two‐sample Mendelian randomization approach was utilized to explore potential causal relationships between mitochondrial DNA copy number (mtDNA‐CN) and ovary‐related reproductive disorders (ORRDs), including ovarian dysfunction, ovarian cyst, polycystic ovary syndrome (PCOS), premature ovarian ...
Ke Peng +4 more
wiley +1 more source
International Journal of Gynecology &Obstetrics, EarlyView.Abstract Objectives Spontaneous premature ovarian insufficiency (POI) is a condition characterized by the cessation of ovarian function before age 40, unrelated to medical interventions. It affects approximately 3.5% of women worldwide and can result in significant emotional, physical, and social consequences.
Maria Patricia Roman +2 more
wiley +1 more source
Journal of Family and Reproductive Health, 2017 Objective: To evaluate whether systemic inflammatory markers (neutrophil to lymphocyte ratio (NLR), platelet to lymphocyte ratio (PLR) and red blood cell distribution width (RDW) to platelet ratio (RPR)) can be used as reliable markers for the diagnosis ...
Gülşah Ilhan +6 more
doaj
International Journal of Gynecology &Obstetrics, EarlyView.Abstract Objective Up to 14% of women with early‐stage endometrial carcinoma (EEC) are diagnosed before menopause. Although ovarian preservation (OP) within surgical staging might avoid surgical menopause, its rate remains low in clinical practice, probably because the impact of OP on survival outcomes is unclear.
Antonio Raffone +12 more
wiley +1 more source
Effectiveness of Instructional Guidelines on Awareness and Perception of Premature Ovarian Insufficiency Women regarding Stem Cell- Based Ovarian Regeneration [PDF]
Egyptian Journal of Health CareBackground: Globally, reproductive aging is increasing and is inextricably linked to aging in general. Premature ovarian insufficiency (POI), which has primarily had an idiopathic etiology up to this point, is an extreme manifestation of reproductive ...
Doaa Lotfi Afifi Alqersh, Hanan E. Nada
doaj +1 more source