Results 71 to 80 of about 21,998 (244)
Selenium‐Based Nanoplatforms: An Emerging Theranostic Paradigm for Gynecological Cancers
Advanced Science, EarlyView.This reivew summarizes Selenium as a multifunctional anticancer regulator in gynecological cancers. It reduces tumor risk, enhances therapeutic efficacy, and reduces treatment toxicity. Selenium also overcomes chemoraditherapy resistance, improving overall treatment outcomes. ABSTRACT Gynecological cancers present significant therapeutic challenges due
Hejing Liu +9 more
wiley +1 more source
Mitochondrial disease and endocrine dysfunction [PDF]
, 2017 Mitochondria are critical organelles for endocrine health; steroid hormone biosynthesis occurs in these organelles and they provide energy in the form of ATP for hormone production and trafficking.
Achermann, JC +4 more
core
Advanced Science, EarlyView.ABSTRACT Tumor immune escape is a major barrier to durable cancer immunotherapy, as advanced malignancies create a tumor microenvironment (TME) that preferentially exhausts and disables T cell responses. While most approved cell therapies are T cell‐based, this limitation motivates the exploration of an alternative effector cell platform.
Tereza Kochs +4 more
wiley +1 more source
Plasma metabolomic characterization of premature ovarian insufficiency
Journal of Ovarian Research, 2023 Background Premature ovarian insufficiency (POI) patients are predisposed to metabolic disturbances, including in lipid metabolism and glucose metabolism, and metabolic disorders appear to be a prerequisite of the typical long-term complications of POI ...
Xing-Yu Zhou +10 more
doaj +1 more source
Defining ovarian reserve to better understand ovarian aging [PDF]
, 2011 Though a widely utilized term and clinical concept, ovarian reserve (OR) has been only inadequately defined. Based on Medline and PubMed searches we here define OR in its various components, review genetic control of OR, with special emphasis on the FMR1
Norbert Gleicher +2 more
core +1 more source
Occult form of premature ovarian insufficiency [PDF]
Gynecological Endocrinology, 2016 Premature ovarian insufficiency (POI) is a life-changing diagnosis, with profound physical and psychological consequences. Despite the description of different genetic, immune and iatrogenic factors of POI, the etiology of most cases of this disease are unexplained, and optimal management strategies are still unclear.
Shestakova I.G. +2 more
openaire +4 more sources
Advanced Intelligent Discovery, EarlyView.Predictive models successfully screen nanoparticles for toxicity and cellular uptake. Yet, complex biological dynamics and sparse, nonstandardized data limit their accuracy. The field urgently needs integrated artificial intelligence/machine learning, systems biology, and open‐access data protocols to bridge the gap between materials science and safe ...
Mariya L. Ivanova +4 more
wiley +1 more source
Premature Ovarian Insufficiency
, 2019 Premature ovarian insufficiency (POI) is defined as the loss of ovarian function before the age of 40 years. Secondary amenorrhea or prolonged oligomenorrhea and primary amenorrhea may be the first symptoms and are the most common complains of POI patients.
Podfigurna, Agnieszka +3 more
+6 more sources
Early Menarche, Nulliparity, and the Risk for Premature and Early Natural Menopause [PDF]
, 2017 Study question: How the timing of menarche and parity link with premature and early natural 42 menopause? Summary answer: Early menarche (≤11 years) is a risk factor for both premature menopause (final 44 menstrual period, FMP
Alissa Goodman +25 more
core +4 more sources
Risk factors, predictive markers and prevention strategies for intrauterine fetal death. An integrative review [PDF]
, 2020 According to World Health Organization (WHO), fetal death is defined as the death of the fetus prior to its complete expulsion, independent of the duration of pregnancy, thus only ascribing the term stillbirth to fetal deaths in the case of pregnancies ...
Andronache, Liliana Florina +6 more
core +2 more sources