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Premature Ovarian Insufficiency: Past, Present, and Future
Premature ovarian insufficiency (POI) is the loss of normal ovarian function before the age of 40 years, a condition that affects approximately 1% of women under 40 years old and 0.1% of women under 30 years old.
Seung Joo Chon +4 more
doaj +3 more sources
Current Concepts in Premature Ovarian Insufficiency
Premature ovarian insufficiency (POI) is a life-changing diagnosis, with profound physical and psychological consequences. Unfortunately, there are many deficiencies in our understanding of the condition as the underlying etiology and optimum management strategies are poorly understood.
Kate, Maclaran, Nick, Panay
openaire +4 more sources
Premature Ovarian Insufficiency
Premature ovarian insufficiency (POI) is a clinical syndrome defined by the presence of ovarian dysfunction before the age of 40 years. The prevalence of POI is around 1%. The following diagnostic criteria are mostly adopted nowadays: (i) oligo/amenorrhea for at least four months, and (ii) FSH levels > 25 IU/l on two occasions more than four weeks ...
Lambrinoudaki, Irene +3 more
+7 more sources
Premature ovarian insufficiency
The natural lifespan of the ovary is occasionally interrupted by pathological processes; some are known, but many are unknown. Premature ovarian insufficiency (POI) can be a devastating diagnosis for an adolescent or for someone who has yet to start a family.
Sinéad M. McGlacken-Byrne +1 more
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Premature ovarian insufficiency [PDF]
Premature ovarian insufficiency (POI) is a clinical syndrome defined as the loss of ovarian activity before the age of 40. POI is a life-changing diagnosis, with profound physical and psychological consequences. Spontaneous POI affects approximately 1% of women under the age of 40.
Marušić, Jelena +3 more
+7 more sources
Regulation of reproduction via tight control of gonadotropin hormone levels. [PDF]
Mammalian reproduction is controlled by the hypothalamic-pituitary-gonadal axis. GnRH from the hypothalamus regulates synthesis and secretion of gonadotropins, LH and FSH, which then control steroidogenesis and gametogenesis. In females, serum LH and FSH
Coss, Djurdjica
core +1 more source
Early menopause: A hazard to a woman's health [PDF]
Early menopause or premature ovarian insufficiency (POI) is a common cause of infertility in women and affects about one per cent of young women. This disorder has significant psychological sequelae and major health implications.
Castelo-Branco Flores, Camil +1 more
core +1 more source
Background The protein kinase B (AKT)/mammalian target of rapamycin (mTOR) signaling pathway regulates early follicular activation and follicular pool maintenance in female germline cells.
Julia Rehnitz +7 more
doaj +1 more source
Treatment of Girls and Boys with McCune-Albright Syndrome with Precocious Puberty - Update 2017 [PDF]
The most common endocrinopathy associated with McCune-Albright Syndrome (MAS) is peripheral precocious puberty (PP) which occurs far more often in girls than in boys.
Eugster, Erica A., Neyman, Anna
core +1 more source
Spontaneous pregnancy in a patient with premature ovarian insufficiency – case report
Diagnosis of premature ovarian insufficiency is usually sudden and distressful for the patient in terms of facing infertility. However, some patients with POI have intermittent ovarian activity with an overall 5% probability of pregnancy.
Anna Calik-Ksepka +6 more
doaj +1 more source

