Results 41 to 50 of about 516,689 (292)

Successful pregnancy with tripterygium glycoside-induced premature ovarian insufficiency: a case report

open access: yesJournal of International Medical Research, 2019
Premature ovarian insufficiency is characterized by reduced ovarian function in a young woman, resulting in an earlier menopause compared with women with normal ovarian function.
Yuan Yang, Xiao-Ling Ma, Xue-Hong Zhang
doaj   +1 more source

Premature Ovarian Insufficiency - diagnostic and therapeutic challenges [PDF]

open access: yes, 2023
Introduction and purpose: Premature Ovarian Insufficiency (POI) is a rare but serious disease diagnosed in about 1% of women before the age of 40. It is characterized by hypoestrogenism and an increase in the level of the follicle-stimulating hormone ...
Tomasik, Mikołaj   +9 more
core  

STUDY OF PRIMORDIAL FOLLICLE, CORPORA LUTEA AND Fmr1 mRNA LEVELS FROM OVARIUM OF Fmr1 GENE PREMUTATION MICE [PDF]

open access: yes, 2010
Background : The FMR1 gene involves in fragile X-associated disorders (FAD), including the fragile X mental retardation syndrome, primary ovarian insufficiency (POI) and Fragile X associated tremor/ataxia syndrome.
Santoso, Santoso
core   +1 more source

Premature Ovarian Insufficiency: A Review

open access: yesEuropean Medical Journal Reproductive Health, 2019
Premature ovarian insufficiency is waning of ovarian function before the age of 40 years. This hypoestrogenic state is characterised by menstrual irregularities and loss of fertility in the patient.
Avantika Gupta   +2 more
doaj   +1 more source

The need to identify novel biomarkers for prediction of premature ovarian insufficiency (POI)

open access: yesMiddle East Fertility Society Journal, 2022
Background Premature ovarian failure (POF)/premature ovarian insufficiency (POI) is characterized by disrupting ovarian function under 40 years old. A major health problem of this disorder is female infertility. There are no proven treatments to increase
Roya Kabodmehri   +3 more
doaj   +1 more source

Cardiometabolic health in premature ovarian insufficiency [PDF]

open access: yesClimacteric, 2021
Premature ovarian insufficiency (POI) is an increasing public health problem with a prevalence now approaching 4%. POI results in adverse effects on the skeleton and central nervous system as well as disturbances of metabolic and cardiological factors that predispose to a major increased risk of cardiovascular disease (CVD).
J. C. Stevenson   +6 more
openaire   +3 more sources

The risk factors, pathogenesis and treatment of premature ovarian insufficiency

open access: yesJournal of Ovarian Research
Premature ovarian insufficiency (POI) is a prevalent condition that impacts female reproductive health and overall well-being. It is characterized by ovarian dysfunction, estrogen deficiency, and increased gonadotropin levels in women under 40 years old.
Yan-Jing Huang   +7 more
semanticscholar   +1 more source

AARS2-catalyzed lactylation induces follicle development and premature ovarian insufficiency

open access: yesCell Death Discovery
Lactate, a metabolite which is elevated in various developmental and pathological processes, exerts its signal through alanyl tRNA synthetases (AARS)-catalyzed protein lactylation.
Zhi-Ling Zhang   +10 more
semanticscholar   +1 more source

Expression profiles of miR-23a and miR-146a in the peripheral blood of women with premature ovarian insufficiency

open access: yesEinstein (São Paulo)
Objective This study aimed to analyze the expression profiles of miR-23a and miR-146a in women with premature ovarian insufficiency and to evaluate their value as biomarkers of the disease for early diagnosis and prognosis, as well as effective ...
Thérèse Rachell Theodoro   +5 more
doaj   +1 more source

Novel bone morphogenetic protein 15 (BMP15) gene variants implicated in premature ovarian insufficiency

open access: yesReproductive Biology and Endocrinology, 2022
Background Bone morphogenetic protein 15 (BMP15) is expressed in oocytes and plays a crucial role in the reproduction of mono-ovulating species. In humans, BMP15 gene mutations lead to imperfect protein function and premature ovarian insufficiency.
Fatemeh Afkhami   +3 more
doaj   +1 more source

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