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Premature Ovarian Insufficiency
Premature ovarian insufficiency (POI) is a clinical syndrome defined by the presence of ovarian dysfunction before the age of 40 years. The prevalence of POI is around 1%. The following diagnostic criteria are mostly adopted nowadays: (i) oligo/amenorrhea for at least four months, and (ii) FSH levels > 25 IU/l on two occasions more than four weeks ...
Lambrinoudaki, Irene +3 more
+8 more sources
Premature ovarian insufficiency [PDF]
Premature ovarian insufficiency (POI) is a clinical syndrome defined as the loss of ovarian activity before the age of 40. POI is a life-changing diagnosis, with profound physical and psychological consequences. Spontaneous POI affects approximately 1% of women under the age of 40.
Marušić, Jelena +4 more
+6 more sources
Supplemental information from: "Homozygous variant in KASH5 causes premature ovarian insufficiency by disordered meiotic homologous pairing"
Qian Zhang (12777767)
core +1 more source
Fertility preservation for girls and young women with cancer: population-based validation of criteria for ovarian tissue cryopreservation [PDF]
Background: Ovarian tissue cryopreservation with later reimplantation has been shown to preserve fertility in adult women, but this approach remains unproven and experimental in children and adolescents.
Edgar, Angela E +8 more
core +1 more source
Ovarian tissue and oocyte cryopreservation prior to iatrogenic premature ovarian insufficiency.
Gonadotoxic treatments like chemotherapy or radiotherapy and ovarian surgery may result in an accelerated depletion of the ovarian reserve and subsequent premature ovarian insufficiency.
Donnez, Jacques +5 more
core +1 more source
Intraovarian platelet-rich plasma: current status
Background The successful use of PRP in regenerative medicine has led investigators to study its effect in the treatment of conditions like decreased ovarian reserve, poor responders, and premature ovarian insufficiency.
Aboubakr Mohamed Elnashar
doaj +1 more source
Alzheimer’s Disease and Premature Ovarian Insufficiency
Estradiol promotes neuronal growth, transmission, survival, myelinization, plasticity, synaptogenesis, and dendritic branching and it improves cognitive function.
Svetlana Vujović +6 more
doaj +1 more source
Premature Ovarian Insufficiency - diagnostic and therapeutic challenges [PDF]
Introduction and purpose: Premature Ovarian Insufficiency (POI) is a rare but serious disease diagnosed in about 1% of women before the age of 40. It is characterized by hypoestrogenism and an increase in the level of the follicle-stimulating hormone ...
Tomasik, Mikołaj +9 more
core
Practical Prediction Model for Ovarian Insufficiency after Radiation
Objective The present study aimed to develop a useful mathematical model that predicts the age at which premature ovarian insufficiency might occur after teletherapy radiation.
Gabriel Oliveira Bernardes Gil +9 more
doaj +1 more source
Plain language summary Premature ovarian insufficiency is the onset of premature menopause in individuals less than 40-years-old. Previous research has shown that there is a higher risk of premature ovarian insufficiency in adolescent and young adult ...
Sydney B. Flatt +4 more
doaj +1 more source

