Results 41 to 50 of about 21,624 (243)

Recognizing menopause in women with amenorrhea induced by cytotoxic chemotherapy for endocrine-responsive early breast cancer. [PDF]

, 2012
Cytotoxic anticancer treatment may induce amenorrhea or menopause to a variable extent. These side effects may not only impair or impede fertility but also cause sexual dysfunction, bone loss, and menopausal symptoms, with a strikingly negative effect on
Appetecchia, M, Barnabei, A, Corsello, SM., De Vecchis, L, Strigari, L, Torino, F   +5 more
core   +1 more source

Short oestrous cycles in sheep during anoestrus involve defects in progesterone biosynthesis and luteal neovascularisation [PDF]

, 2014
Anoestrous ewes can be induced to ovulate by the socio-sexual, 'ram effect'. However, in some ewes the induced ovulation is followed by an abnormally short luteal phase causing a so called, "short cycle".
Acritopoulou, C Fabre Nys, Cahill, Chanvallon, Chemineau, Chemineau, Dickson, Dickson, H M Brown, Hazzard, Hinney, J Cognié, Koos, Land, Lassoued, Livak, Martin, Martin, Pearce, Pearce, Pritts, R J Scaramuzzi, Richards, Ungerfeld, Weems, Weems, Wulff, Wulff, Wulff   +28 more
core   +3 more sources

Oligogenic basis of premature ovarian insufficiency: an observational study

Journal of Ovarian Research
Background The etiology of premature ovarian insufficiency, that is, the loss of ovarian activity before 40 years of age, is complex. Studies suggest that genetic factors are involved in 20–25% of cases.
Panpan Long, Le Wang, Hangjing Tan, Ruping Quan, Zihao Hu, Minghua Zeng, Ziheng Deng, Hualin Huang, Jonathan Greenbaum, Hongwen Deng, Hongmei Xiao   +10 more
doaj   +1 more source

Thyroxine-binding globulin: investigation of microheterogeneity [PDF]

, 1981
Preparations of T4-binding globulin (TBG) from human serum was performed using only two affinity chromatography steps. Purity of the protein was demonstrated by a single band in overloaded disc and sodium dodecyl sulfate electrophoresis, equimolar ...
Gärtner, Roland, Henze, R., Horn, K., Pickardt, C. R., Scriba, Peter Christian   +4 more
core   +1 more source

Pathogenic Neurofibromatosis type 1 gene variants in tumors of non‐NF1 patients and role of R1276

FEBS Open Bio, EarlyView.
Somatic variants of the neurofibromatosis type 1 (NF1) gene occur across neoplasms without clinical manifestation of the disease NF1. We identified emerging somatic pathogenic NF1 variants and hotspots, for example, at the arginine finger 1276. Those missense variants provide fundamental information about neurofibromin's role in cancer.
Mareike Selig, Swanhild Lohse, Sara Elahi, Nils Hartmann, Stefanie Deckert, Shutian Si, Alexander Desuki, Anja Harder   +7 more
wiley   +1 more source

DNA methylation-based age prediction and telomere length in white blood cells and cumulus cells of infertile women with normal or poor response to ovarian stimulation. [PDF]

, 2018
An algorithm assessing the methylation levels of 353 informative CpG sites in the human genome permits accurate prediction of the chronologic age of a subject.
Bedard, Jenna, Landis, Jessica, Marin, Diego, Morin, Scott J., Scott, Richard T., Seli, Emre, Tao, Xin, Zhan, Yiping   +7 more
core   +1 more source

The Genetics of Non-Syndromic Primary Ovarian Insufficiency: A Systematic Review [PDF]

, 2019
Several causes for primary ovarian insufficiency (POI) have been described, including iatrogenic and environmental factor, viral infections, chronic disease as well as genetic alterations.
Arduino, Bruno, CARLEA, ANNUNZIATA, D'Alessandro, Pietro, De Marco, Carmela, De Vivo, Valentino, Improda, Francesco Paolo, Lico, Daniela, Rania, Erika, Saccone, Gabriele, Venturella, Roberta, Viglietto, Giuseppe, Zullo, Fulvio   +11 more
core   +1 more source

Cross‐Scale Hierarchical Targeted Delivery System Based on Small‐Scale Magnetic Robots

Advanced Robotics Research, EarlyView.
This article reviews a cross‐scale hierarchical targeted delivery system that integrates magnetic continuum robots and magnetic microrobots. By combining rapid long‐range navigation with precise microscale targeting, the system overcomes key limitations of single‐scale approaches.
Junjian Zhou, Zhiqiang Chen, Yuanbiao Ma, Zhiqiang Tang, Qianqian Wang   +4 more
wiley   +1 more source

Birth weight and premature ovarian insufficiency: a systematic review and meta-analysis

Journal of Ovarian Research
Objective To comprehensively evaluate the effect of low birth weight on premature ovarian insufficiency. Methods We performed a systematic review of the literature by searching MEDLINE, EMBASE, Web of Science, Scopus, Wanfang and CNKI up to August 2023 ...
Chengyang Jiang, Tongqing Gao, Yuwei Wang, Wenqiang Yang, Huan Huang, Yushan Li, Xinghai Yang   +6 more
doaj   +1 more source

Telomere length in granulosa cells and leukocytes: a potential marker of female fertility? A systematic review of the literature

Journal of Ovarian Research, 2020
In the context of a continuously increased delay of motherhood and of an increase of the incidence of premature ovarian failure, it is of the greatest interest to dispose of a predictive marker of the duration of the fertility window.
Anne-Julie Fattet, Simon Toupance, Simon N. Thornton, Nicolas Monnin, Jean-Louis Guéant, Athanase Benetos, Isabelle Koscinski   +6 more
doaj   +1 more source