Results 21 to 30 of about 12,258 (117)

Neurotoxicity [PDF]

, 2014
Neurotoxicity refers to the direct or indirect effect of chemicals that disrupt the nervous system of humans or animals. Numerous chemicals can produce neurotoxic diseases in humans, and many more are used as experimental tools to disturb or damage the ...
Brust, Creeley, Feldman, Grandjean, Herken, Panzica, Parent, Pessah, Rice, Román, Spencer, Spencer, Tu, Vinken, Yasui, Zawia   +15 more
core   +2 more sources

Factors associated with avoidable hospitalisation of children younger than 2 years old: the 2006 Brazilian National Demographic Health Survey [PDF]

, 2015
INTRODUCTION: Ambulatory Care Sensitive Conditions (ACSC) are conditions for which hospitalisation is thought to be avoidable with the use of effective preventive care and early disease management.
José A. A. C. Taddei, Laís Amaral Mais, Tulio Konstantyner   +2 more
core   +1 more source

The Impact of External Factors on the Epigenome: In Utero and over Lifetime [PDF]

, 2016
Epigenetic marks change during fetal development, adult life, and aging. Some changes play an important role in the establishment and regulation of gene programs, but others seem to occur without any apparent physiological role.
Fernández Fernández, Agustín, Fernández Morera, Juan Luis, García Toraño, Estela, García, M. G., Niño García, Pilar   +4 more
core   +3 more sources

Evo-devo of human adolescence: beyond disease models of early puberty [PDF]

, 2013
Despite substantial heritability in pubertal development, much variation remains to be explained, leaving room for the influence of environmental factors to adjust its phenotypic trajectory in the service of fitness goals.
A Templeton, AB Arquitt, AB Migliano, AK Pesonen, AS Parent, B Bogin, B Campbell, BH Smith, BJ Ellis, BJ Ellis, BJ Ellis, BJ Ellis, BS Zemel, C Ankarberg Lindgren, C Cooper, C Tardieu, CC Chen, CL Sisk, F Deng, GB Cutler Jr, GB Muller, GE Weisfeld, J Belsky, J Belsky, J Belsky, J Belsky, J Belsky, J Belsky, J Belsky, J Belsky, J Belsky, J Bowlby, J Bowlby, J James, J Tinggaard, Jay Belsky, JC Wingfield, JL Locke, JM Tither, KB Simondon, KK Ong, KK Ong, KO Klein, L Aksglaede, LA Proos, M Celio, M Del Giudice, M Krstevska-Konstantinova, M Mead, M Suzuki, ME Pembrey, MR Palmert, N Howell, NM Cameron, PD Gluckman, PD Kroboth, PJ Hunt, RG Westendorp, S White, SB Manuck, SC Stearns, W Arlt, W Copeland, WT Boyce, Z Hochberg, Z Hochberg, Z Hochberg, Z Hochberg, Z Hochberg, Ze'ev Hochberg   +69 more
core   +2 more sources

Consequences of Postnatally Elevated Insulin-Like Growth Factor-II in Transgenic Mice: Endocrine Changes and Effects on Body and Organ Growth. [PDF]

, 1994
Insulin-like growth factor-II (IGF-II) is an important regulator of embryonic growth and differentiation, but its function in postnatal life is unclear. To address this point, we generated transgenic mice harboring fusion genes in which a human IGF-II
Blum, Werner F., Brem, Gottfried, Föll, Jürgen, Kramer, Rainer, Wolf, Eckhard   +4 more
core   +1 more source

Long-Term Effects of the Periconception Period on Embryo Epigenetic Profile and Phenotype: The Role of Stress and How This Effect Is Mediated [PDF]

, 2017
Stress represents an unavoidable aspect of human life, and pathologies associated with dysregulation of stress mechanisms - particularly psychiatric disorders - represent a significant global health problem. While it has long been observed that levels of
A Barbazanges, A Harris, A Kalueff V, A Stewart, AB Rodgers, AB Vaage, AE Arrant, AJ Bradley, AM Brunner, AP Harris, AS Brown, AS Khashan, B Blondeau, BA Barton, BG Dias, BJ Kolber, C Faravelli, C Heim, C Jensen Peña, C Lilliecreutz, C Wahlquist, CL Howerton, CL Howerton, DC Love, DE Stewart, DL Champagne, E Conradt, E Ottaviani, EC Cottrell, EL Marczylo, FCR Zucchi, G Liang, GM Miller, GP Chrousos, H Palma-Gudiel, H Palma-Gudiel, I Babiak, I Cantone, J Cachat, J Weinberg, JL Melville, K Gapp, KA Fenoglio, KGC Hellemans, KI Gabriel, KM Aberg, KM Ogilvie, KM Radtke, KV Morris, L Prut, LAM Welberg, LB Smith, LJ Luense, LK Takahashi, M Bourin, M Carter, M Mittelbrunn, M Teperek, MC Leal, MT Kinsella, NE Zachara, P Vella, PM Schulte, R Couto-Moraes, R Yehuda, RJ Egan, S Panneerdoss, S Smith, SC Cramer, SF Sorrells, SJ Lupien, SJ Lupien, SL Hollins, SN Vigod, SR Alt, T Janevic, T Vos, U Grossniklaus, V Grandjean, V Kumar, VH Nargund, Y Yao, Z Michailidou   +82 more
core   +1 more source

Trabecular bone ontogeny of the human talus

The Anatomical Record, EarlyView.
Abstract Studies of trabecular ontogeny may provide insight into the factors that drive healthy bone development. There is a growing understanding of how the juvenile skeleton responds to these influences; however, gaps in our knowledge remain. This study aims to identify ontogenetic trabecular patterns and regional changes during development within ...
Rebecca A. G. Reid, Catriona Davies, Craig Cunningham   +2 more
wiley   +1 more source

Testing the Integrated Theory of Health Behaviour Change for Postpartum Weight Management [PDF]

, 2011
Aim.  This is a report of a correlational study to test the Integrated Theory of Health Behaviour Change within the context of postpartum weight self‐management including the impact of race/ethnicity and weight classification. Background.
Brondino, Michael J, Ryan, Polly, Traxel, Nicole, Weiss, Marianne   +3 more
core   +2 more sources

Fetal Pain Perception: Legislative Assertions and Developmental Neuroscience

Annals of the Child Neurology Society, EarlyView.
ABSTRACT Background Pain perception is a conscious experience, but neither pain nor consciousness is defined in the developing human fetus. Emergent consciousness may be regarded as a phenomenon that ultimately arises from an essential minimum of functional neuronal connectivity. Proposed U.S.
William D. Graf, Timothy M. Crombleholme, Leon G. Epstein, Dawn Gano, Phillip L. Pearl, Timothy V. Salomons, Mark S. Scher, Elise Turk, Klaus‐Peter Zimmer, Harvey B. Sarnat   +9 more
wiley   +1 more source

Native American Pregnant and Postpartum People's Experiences of Discrimination During Perinatal Care: A Qualitative Study

BJOG: An International Journal of Obstetrics &Gynaecology, EarlyView.
ABSTRACT Objective Indigenous pregnant and postpartum people are more likely to experience severe maternal morbidity (SMM) and mortality than non‐Indigenous groups. We sought to explore how community and societal factors, culture, and resilience impact Native American individuals' pregnancy experiences and might offer insights to address inequities in ...
Jennifer L. Murray, Heather Tanana, Torri D. Metz, Reham Perry, Elisabeth R. Kimball, Patrick Galyean, Susan Zickmund, Michael W. Varner, Michelle P. Debbink   +8 more
wiley   +1 more source