Results 91 to 100 of about 209,608 (344)

Metabotropic glutamate 2/3 receptors and epigenetic modifications in psychotic disorders: a review [PDF]

open access: yes, 2016
Schizophrenia and Bipolar Disorder are chronic psychiatric disorders, both considered as "major psychosis"; they are thought to share some pathogenetic factors involving a dysfunctional gene x environment interaction.
Grayson, Danis R   +4 more
core   +2 more sources

Prenatal Maternal Stress and the Risk of Asthma in Children [PDF]

open access: yesFrontiers in Pediatrics, 2017
Emerging evidence indicate that maternal prenatal stress (MPS) can result in a range of long-term adverse effects in the offspring. The underlying mechanism of MPS is not fully understood. However, its complexity is emphasized by the number of purportedly involved pathways namely, placental deregulated metabolism of maternal steroids, impaired ...
Douros, K.   +5 more
openaire   +4 more sources

Tracking of [14C]Polystyrene Nanoplastics in Pregnant Mice

open access: yesAdvanced Science, EarlyView.
This study investigates [14C]polystyrene nanoplastic ([14C]PS) translocation in late‐stage pregnant mice after intranasal (0.5 mg of [14C]PS on GD12, GD14, and GD16, n = 6) and intravenous administration (1.5 mg of [14C]PS on GD16, n = 6). 14C‐radiolabel allows quantitative tracking of unmodified polystyrene nanoplastics.
Olga Khaybullina   +2 more
wiley   +1 more source

Correction to: Spectrum of PAH gene variants among a population of Han Chinese patients with phenylketonuria from northern China

open access: yesBMC Medical Genetics, 2018
Following publication of the original article [1], the authors reported an error in Table 3 on page 4. Variant No. 18 should be “ p.Ser339Phe c.1016C>T ” (as given in Number 117 of Additional file 2).
Ning Liu   +8 more
doaj   +1 more source

Prenatal exposure to methadone or buprenorphine: Early childhood developmental outcomes. [PDF]

open access: yes, 2018
BACKGROUND: Methadone and buprenorphine are recommended to treat opioid use disorders during pregnancy. However, the literature on the relationship between longer-term effects of prenatal exposure to these medications and childhood development is both ...
Coyle, Mara G.   +8 more
core   +1 more source

Prospective Longitudinal Study of the Pregnancy DNA Methylome: The US Pregnancy, Race, Environment, Genes (PREG) Study [PDF]

open access: yes, 2018
Purpose The goal of the Pregnancy, Race, Environment, Genes study was to understand how social and environmental determinants of health (SEDH), pregnancy-specific environments (PSE) and biological processes influence the timing of birth and account for ...
Amstadter, Ananda B.   +9 more
core   +2 more sources

Paternal Caffeine Exposure Programs Offspring Stress Vulnerability via Sperm Dlk1‐Dio3 Imprinting‐Directed Remodeling of a Novel Neural Circuit

open access: yesAdvanced Science, EarlyView.
The study elucidates that paternal preconception stress can drive offspring hyperresponsivity of the stress system via hypomethylation of a specific DNA region in sperm. This key link is confirmed in a cohort of prospective fathers: the epigenetic alteration is associated with elevated stress hormone levels.
Mengxi Lu   +10 more
wiley   +1 more source

Determine the Influence of Prenatal Stress on Fetal Development

open access: yesLiaquat Medical Research Journal, 2020
Prenatal stress is an epigenetic factor which can produce long-lasting alterations in brain structures and body functions. The objective of this is to examine the ratio of prenatal stress among pregnant women.
Anila Sharif
doaj  

Spectrum of PAH gene variants among a population of Han Chinese patients with phenylketonuria from northern China

open access: yesBMC Medical Genetics, 2017
Background Phenylketonuria (PKU), which primarily results from a deficiency of phenylalanine hydroxylase (PAH), is one of the most common inherited inborn errors of metabolism that impairs postnatal cognitive development.
Ning Liu   +8 more
doaj   +1 more source

Psychological, endocrine and polygenic predictors of emotional well-being during the COVID-19 pandemic in a longitudinal birth cohort

open access: yesStress, 2023
The COVID-19 pandemic severely affected the lives of families and the well-being of both parents and their children. Various factors, including prenatal stress, dysregulated stress response systems, and genetics may have influenced how the stress caused ...
Thao Nguyen   +12 more
doaj   +1 more source

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