Results 121 to 130 of about 35,022 (176)
Some of the next articles are maybe not open access.
Related searches:
Related searches:
Catalytic prenylation and reverse prenylation of aromatics
Trends in Chemistry, 2022Xiang-Ting Min +2 more
exaly +2 more sources
Regulation of protein prenylation
Biomedicine and Pharmacotherapy, 2023 Prenyltransferases (PTases) are known to play a role in embryonic development, normal tissue homeostasis and cancer by posttranslationally modifying proteins involved in these processes. They are being discussed as potential drug targets in an increasing number of diseases, ranging from Alzheimer's disease to malaria.
Hagen Bachmann, Dominik Jung
exaly +3 more sources
Probes for protein prenylation [PDF]
Nature Methods, 2019 Doerr Allison, Allison Doerr
exaly +3 more sources
BioEssays, 1992
AbstractThe prenylated proteins represent a newly discovered class of post‐translationally modified proteins. The known prenylated proteins include the oncogene product p21ras and other low molecular weight GTP‐binding proteins, the nuclear lamins, and the γ subunit of the heterotrimeric G proteins.
M, Sinensky, R J, Lutz
openaire +2 more sources
AbstractThe prenylated proteins represent a newly discovered class of post‐translationally modified proteins. The known prenylated proteins include the oncogene product p21ras and other low molecular weight GTP‐binding proteins, the nuclear lamins, and the γ subunit of the heterotrimeric G proteins.
M, Sinensky, R J, Lutz
openaire +2 more sources
Prenylation: A Critical Step for Biomanufacturing of Prenylated Aromatic Natural Products
Journal of Agricultural and Food Chemistry, 2023Prenylated aromatic natural products (PANPs) have received much attention due to their biomedical benefits for human health. The prenylation of aromatic natural products (ANPs), which is mainly catalyzed by aromatic prenyltransferases (aPTs), contributes significantly to their structural and functional diversity by providing higher lipophilicity and ...
Ting An, Xudong Feng, Chun Li
openaire +2 more sources
Inhibitors of prenyl transferases
Current Opinion in Oncology, 1997Because farnesylation of Ras is required for its cancer-causing activity, several classes of farnesyl transferase inhibitors have recently been developed as potential anticancer drugs. During the last 12 months, important advances have been made in this field.
S, Sebti, A D, Hamilton
openaire +2 more sources
Prenylated Flavonoids: Pharmacology and Biotechnology
Current Medicinal Chemistry, 2005Within the flavonoid class of natural products the prenylated sub-class is quite rich in structural variety and pharmacological activity. In the last twenty years a huge number of new structures has been reported, mostly from Leguminosae and Moraceae, with few coming from other genera.
BOTTA, Bruno +4 more
openaire +5 more sources
ChemInform Abstract: A STUDY OF DE‐O‐PRENYLATION OF O‐PRENYL‐ AND C‐PRENYL‐O‐PRENYLPOLYPHENOLS
Chemischer Informationsdienst, 1978AbstractDer Prenylether (Ia) wird in wäßrigem Morpholin zum Phenol (Ib) gespalten.
A. C. JAIN, D. K. TULI, A. KOHLI
openaire +1 more source
Antigenic Prenylated Peptide Conjugates and Polyclonal Antibodies To Detect Protein Prenylation
Bioconjugate Chemistry, 2004Posttranslational modification of proteins with farnesyl and geranylgeranyl groups is a required modification for signaling proteins that includes the small GTPases in the Ras, Rho, and Rab families, heterotrimeric G proteins, and nuclear lamin proteins.
Xiao-hui, Liu +3 more
openaire +2 more sources