Results 111 to 120 of about 38,918 (216)

Role of inhibition of protein prenylation in the cholesterol-dependent and cholesterol-independent effects of simvastatin

, 2006
Statins are widely used to treat hypercholesterolemia. Statins inhibit cholesterol biosynthesis, thereby activating genes involved in cholesterol homeostasis, which are under the control of the Sterol Regulatory Element (SRE).
Volk, Catherine B.
core  

Probes for protein prenylation [PDF]

Nature Methods, 2019
openaire   +2 more sources

Enzymology and Biology of CaaX Protein Prenylation

, 2014
[[abstract]]Protein prenylation refers to a type of lipid modification in which tither a 15-carbon farnesyl or 20-carbon geranylgeranyl isoprenoid is linked via a thioether bond to specific cysteine residues of proteins.
Fu, HW;Casey, PJ
core  

Downregulation of prenylation machinery genes in peripheral blood of patients with Parkinson's disease: A pilot study. [PDF]

IBRO Neurosci Rep
Tabatabaie MJ, Eslami S, Abak A, Ghafouri-Fard S.   +3 more
europepmc   +1 more source

Studies of protein prenylation in living systems: implications toward the better understanding of diseases

, 2012
University of Minnesota Ph.D. dissertation. August 2012. Major: Chemistry. Advisor: Dr. Mark D. Distefano. 1 computer file (PDF); xv, 199 pages, appendices A-B.Protein prenylation is a post-translational modification that is present in a large number of ...
Ochocki, Joshua Daniel
core  

Alumina-Templated ortho-Prenylation of Phenols. [PDF]

Nat Commun
Piotrowski ML, Irwin LC, Darveau P, Zhang X, Hoford S, Vemulapalli S, Breault K, Johnson JW, Dudding T, Magolan J.   +9 more
europepmc   +1 more source

Biosynthesis of O-Prenylated Chaetophenols Triggers Nonenzymatic Pathways toward Structural Diversity. [PDF]

Org Lett
Matsui H, Morishita Y, Homma Y, Tsukada K, Yamamoto T, Morita S, Oshima Y, Ozaki T, Asai T.   +8 more
europepmc   +1 more source

Protein farnesylation: from molecular mechanisms to therapeutic targeting in cancer, aging, and beyond. [PDF]

Front Pharmacol
Lou J, Zhang D, Wang Y.
europepmc   +1 more source

Mechanisms influencing transient cytoplasmic protein targeting to intracellular lipid droplets. [PDF]

Biochem Soc Trans
Laws JL, Monson EA, Wallace LA, Helbig KJ, Reddington CJ.   +4 more
europepmc   +1 more source

Host prenylation promotes membrane association of the <i>Salmonella</i> effector GtgE during infection. [PDF]

Microbiology (Reading)
Cattelan N, Yu H, Przybyszewska K, Solano-Collado V, Colamarino R, Baldassarre M, Spanò S.   +6 more
europepmc   +1 more source