Results 91 to 100 of about 44,008 (221)
Prenylates Xanthones from Garcinia xanthochymus.
ChemInform, 2003 AbstractFor Abstract see ChemInform Abstract in Full Text.
Wisinee, Chanmahasathien +6 more
openaire +3 more sources
Context‐Dependent Chemoselectivity of Aromatic C‐Methyltransferases
ChemBioChem, Volume 27, Issue 8, April 2026.Chemoselectivity is context‐dependent: The SAM‐dependent C‐MTs SfmM2 and NapB5 from streptomycetes catalyze the C‐ and/or O‐dimethylation of aromatic substrates, including l‐tyrosine and flavonoids. C‐methylation activity requires precise substrate recognition and positioning to ensure proximity between the target carbon nucleophile and the methyl ...
Juliane Breiltgens +4 more
wiley +1 more source
Cholesterol 24S-Hydroxylase overexpression inhibits the liver X receptor (LXR) pathway by activating small guanosine triphosphate-binding proteins (sGTPases) in neuronal cells [PDF]
, 2014 The neuronal-specific cholesterol 24S-hydroxylase (CYP46A1) is important for brain cholesterol elimination. Cyp46a1 null mice exhibit severe deficiencies in learning and hippocampal long-term potentiation, suggested to be caused by a decrease in ...
Björkhem, Ingemar +7 more
core +1 more source
Molecular Basis for Rab Prenylation [PDF]
The Journal of Cell Biology, 2000 Rab escort proteins (REP) 1 and 2 are closely related mammalian proteins required for prenylation of newly synthesized Rab GTPases by the cytosolic heterodimeric Rab geranylgeranyl transferase II complex (RabGG transferase). REP1 in mammalian cells is the product of the choroideremia gene (CHM).
C, Alory, W E, Balch
openaire +2 more sources
Food Science &Nutrition, Volume 14, Issue 4, April 2026.Halopithys incurva is a red macroalga distributed across the Mediterranean Sea and North‐East Atlantic, with occasional reports from the Indian Ocean. It exhibits a rich chemical diversity, including isoflavones, bromophenols, MAAs, pigments, phycobiliproteins, primary metabolites, and neuroactive compounds.
Youssra Aalilou +9 more
wiley +1 more source
Veterinary ResearchLawsonia intracellularis, a Gram-negative obligate intracellular bacterium causing porcine proliferative enteropathy, possesses a type III secretion system (T3SS), yet only a handful of its substrates have been experimentally characterized. In this study,
Yuanxiu Zhong +4 more
doaj +1 more source
Tackling resistance: Emerging antimalarials and new parasite targets in the era of elimination [version 1; referees: 2 approved] [PDF]
, 2018 Malaria remains a significant contributor to global human mortality, and roughly half the world’s population is at risk for infection with Plasmodium spp. parasites.
Matthews, Emily S, Odom John, Audrey R
core +2 more sources
7-Isopentenyloxycoumarin: What Is New across the Last Decade
Molecules, 2020 7-Isopentenyloxycoumarin is among the most widespread naturally occurring prenyloxy umbelliferone derivatives. This secondary metabolite of mixed biosynthetic origin has been typically isolated from plants belonging to several genera of the Rutaceae and ...
Francesca Preziuso +6 more
doaj +1 more source
Journal of Cellular and Molecular Medicine, Volume 30, Issue 7, April 2026.ABSTRACT Adenomyosis is a prevalent disorder of the archimetra, historically conflated with endometriosis but possessing a unique pathobiological trajectory. This review synthesises current molecular evidence to propose a unified mechanistic framework initiated by tissue injury and repair (TIAR), aberrant stem cell activation, or de novo metaplasia ...
Jiang Yang +6 more
wiley +1 more source
Biotechnologie, Agronomie, Société et Environnement, 2014 Protein prenylation in insects: a potential target for the development of bio-rational insecticides targeting the Lepidoptera?. Short-chain prenyltransferases (farnesyl diphosphate synthase [FPPS] and geranylgeranyl diphosphate synthase [GGPPS]) and ...
Barbar, A., Cusson, M.
doaj