Results 71 to 80 of about 35,022 (176)

Effects of hindlimb unloading on the mevalonate and mechanistic target of rapamycin complex 1 signaling pathways in a fast‐twitch muscle in rats

Physiological Reports
Fast‐twitch muscles are less susceptible to disuse atrophy, activate the mechanistic target of rapamycin complex 1 (mTORC1) signaling pathway, and increase protein synthesis under prolonged muscle disuse conditions.
Munehiro Uda, Toshinori Yoshihara, Noriko Ichinoseki‐Sekine, Takeshi Baba   +3 more
doaj   +1 more source

Structure Prediction and Genome Mining‐Aided Discovery of the Bacterial C‐Terminal Tryptophan Prenyltransferase PalQ

Advanced Science
Post‐translational prenylations, found in eukaryotic primary metabolites and bacterial secondary metabolites, play crucial roles in biomolecular interactions.
Azusa Miyata, Sohei Ito, Daisuke Fujinami   +2 more
doaj   +1 more source

Prelamin A prenylation and the treatment of progeria [PDF]

Journal of Lipid Research, 2010
Hutchinson-Gilford progeria syndrome (HGPS) is a rare, sporadic, autosomal dominant disease with phenotypic features of premature aging (1). It is caused by de novo mutations in LMNA that encodes the A-type nuclear lamins, intermediate filament proteins that are components of the nuclear lamina (2, 3).
openaire   +2 more sources

Dual‐Ligand Strategy in Rh‐Catalyzed Sequential Hydrofunctionalization of Valylene

Advanced Science
Controlling regio‐ and chemo‐selectivity in transition‐metal‐catalyzed reactions involving coupling reagents with multiple reactive sites remains a significant challenge.
Yong‐Kang Mei, Su‐Yang Xu, Zhi‐Hui Wang, Ding‐Wei Ji, Qing‐An Chen   +4 more
doaj   +1 more source

A Fungal <i>p</i>-Terphenyl Prenyltransferase for Regioselective <i>C</i>-Prenylation of Flavonoids and Other Compounds Bearing <i>ortho</i>-Dihydroxyphenyl Moieties. [PDF]

J Agric Food Chem
Janzen DJ, Zhou J, Losert S, Li SM.
europepmc   +1 more source

Statins promote muscle metabolic danger and NLRP3-mediated myopathy via lower protein-prenylation and YAP. [PDF]

Sci Adv
Robin N, Barra NG, Foley KP, Li YE, Tamrakar AK, Patoli D, Rebalka IA, Cree T, Bibby K, Nguyen K, Davis R, Chan DY, Duggan BM, Henriksbo BD, Borges ME, Kukje Zada D, Fang H, Marko DM, Gregorevic P, Watt KI, Mills RJ, Sweeney G, Hawke TJ, Py BF, Schertzer JD.   +24 more
europepmc   +1 more source

Protein lipidation in cardiovascular homeostasis, development, and disease. [PDF]

Clin Sci (Lond)
Cully D, Harrison S, Sadovsky M, Miner GE, Edwards W.   +4 more
europepmc   +1 more source

Enzymatic Prenylation of Proteins and Peptides: From Cysteine S-Prenylation to Tryptophan-Selective Biocatalysis. [PDF]

Chemistry
Fujinami D, Ozawa H, Ito S.
europepmc   +1 more source

Creation of bioactive non-natural flavonoids via combinatorial prenylation-glycosylation cascades. [PDF]

mLife
Zhang H, Zhang A, Ji J, Yin WB.
europepmc   +1 more source

Organotellurium Probes Enable One-step Single-cell Analysis of Post-translational Modification. [PDF]

J Am Chem Soc
Chen Y, Elbein K, Venkatachalapathy S, Lorimer EL, Sprague-Getsy AM, Auger SA, Maxwell ZA, Rashidian M, Hougland JL, Williams CL, Arriaga EA, Distefano MD.   +11 more
europepmc   +1 more source