Results 71 to 80 of about 1,421 (183)

Evaluation of 147 Kampo prescriptions as novel protein tyrosine phosphatase 1B (PTP1B) inhibitory agents [PDF]

open access: yes, 2014
BACKGROUND: Protein tyrosine phosphatase (PTP) 1B, a negative regulator of the insulin and leptin signaling pathways, is currently considered a promising target for the development of novel therapeutic approaches used to treat insulin-resistant type 2 ...
Kazuo Koike   +3 more
core   +1 more source

The Potent Phytoestrogen 8-Prenylnaringenin: A Friend or a Foe? [PDF]

open access: yes, 2022
8-prenylnaringenin (8-PN) is a prenylated flavonoid, occurring, in particular, in hop, but also in other plants. It has proven to be one of the most potent phytoestrogens in vitro known to date, and in the past 20 years, research has unveiled new effects
Nasri, Atefeh, Pohjanvirta, Raimo
core   +3 more sources

Diversity of secondary metabolites from Genus Artocarpus (Moraceae) [PDF]

open access: yes, 2010
Abstrak. Hakim A. 2010. Keanekaragaman metabolit sekunder Genus Artocarpus (Moraceae). Nusantara Bioscience 2:146-156. Beberapa spesies dari genus Artocarpus (Moraceae) telah diteliti kandungan bahan alamnya.
HAKIM, ALIEFMAN
core   +3 more sources

Characterization of Bioactive Compounds and Evaluation of Antimicrobial Activity of Humulus lupulus (L.) cv. Cascade Leaves Throughout the Growing Season

open access: yesJournal of Sustainable Agriculture and Environment, Volume 4, Issue 3, September 2025.
ABSTRACT Hop (Humulus lupulus L.) is recognised for its abundance of bioactive compounds, which make it a valuable natural resource. While much of the research has focused on the cones, hop leaves remain relatively unexplored, particularly in terms of changes occurring throughout the plant's growing cycle.
Leandra Leto   +13 more
wiley   +1 more source

Phytoestrogens [PDF]

open access: yes, 2004
Collectively, plants contain several different families of natural products among which are compounds with weak estrogenic or antiestrogenic activity toward mammals.
Adlercreutz H   +37 more
core   +1 more source

Genistein in the Prevention and Treatment of Periodontitis: A Review

open access: yesFood Science &Nutrition, Volume 13, Issue 8, August 2025.
Genistein, an isoflavone compound with diverse pharmacological activities, shows potential as an adjunctive therapeutic agent for periodontitis due to its anti‐inflammatory, antioxidant, and osteoprotective properties. Genistein not only mitigates the degradation of periodontal soft tissue but also demonstrates a protective effect on alveolar bone by ...
Yujun Lu   +6 more
wiley   +1 more source

Natural products‐induced cancer cell paraptosis

open access: yesFood Science &Nutrition, Volume 12, Issue 11, Page 9866-9871, November 2024.
Cancer cell can be killed in a programmed way by natural products in a process known as paraptosis.
Haitham Al‐Madhagi
wiley   +1 more source

Prenylflavonoids from the Twigs of Artocarpus nigrifolius.

open access: yesChemical & pharmaceutical bulletin, 2018
Two new prenylated flavones, artocarnin A (2) and carpachromenol (12), together with 13 known prenylflavonoids (1, 3-11, 13-15) were isolated from the twigs of Artocarpus nigrifolius for the first time. Their structures were elucidated by high resolution-electrospray ionization (HR-ESI)-MS, NMR spectroscopic analysis, and in comparison with the ...
Xi, Liu   +8 more
openaire   +2 more sources

Icaritin induces lytic cytotoxicity in extranodal NK/T-cell lymphoma [PDF]

open access: yes, 2015
BACKGROUND: Extranodal NK/T-cell lymphoma (ENKL) is an aggressive hematological malignancy associated with Epstein–Barr virus (EBV) infection. It is often resistant to conventional chemotherapy and has a poor prognosis.
Bobin Chen   +8 more
core   +1 more source

Perspective on the Coevolutionary Role of Host and Gut Microbiota in Polyphenol Health Effects: Metabotypes and Precision Health

open access: yesMolecular Nutrition &Food Research, Volume 68, Issue 22, November 2024.
Polyphenols are xenobiotics (antinutrients and antimicrobials), posing a potential threat to the host and its gut microbiota. Thus, their health effects are a coevolutionary secondary consequence of the host and microbiota metabolism to neutralize them.
Juan Carlos Espín   +5 more
wiley   +1 more source

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