Results 131 to 140 of about 9,170,294 (335)

Emerging role of ARHGAP29 in melanoma cell phenotype switching

Molecular Oncology, EarlyView.
This study gives first insights into the role of ARHGAP29 in malignant melanoma. ARHGAP29 was revealed to be connected to tumor cell plasticity, promoting a mesenchymal‐like, invasive phenotype and driving tumor progression. Further, it modulates cell spreading by influencing RhoA/ROCK signaling and affects SMAD2 activity. Rho GTPase‐activating protein
Beatrice Charlotte Tröster, Melanie Kappelmann‐Fenzl, Anja Katrin Bosserhoff, Nicole Rachinger   +3 more
wiley   +1 more source

Special Characterization and Excellent Antioxidant Capabilities of Zinc Chelated Squid Protein Nanoparticles

Foods
The functional exploration of marine-derived proteins is at the forefront of nutritional research. The Argentine squid protein (ASP) was extracted from Argentine squid carcasses and was hydrolyzed using neutral protease, with the degree of hydrolysis ...
Qiyi Zhou, Tianming Wang, Lixin Liu, Yaqi Kong, Yifan Liu, Wenhui Wu, Xiaozhen Diao   +6 more
doaj   +1 more source

Reducing-agent-free facile preparation of Rh-nanoparticles uniformly anchored on onion-like fullerene for catalytic applications

, 2020
Mayakrishnan Gopiraman, Somasundaram Saravanamoorthy, Sana Ullah, Andivelu Ilangovan, Ick Soo Kim, Ill Min Chung   +5 more
openalex   +2 more sources

Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids

Molecular Oncology, EarlyView.
This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici, Soheil Akbari, Ceyda Caliskan, Canan Celiker, Ozden Oz, Leman Binokay, Gökhan Karakulah, Serif Senturk, Esra Erdal   +8 more
wiley   +1 more source

Assessment of the Characteristics of Corncobs Used for Energy Needs

Agronomy
Due to environmental pollution and global warming, the use of renewable energy sources such as agricultural residues is gaining attention. Corn is the main source of food in many countries, and after harvesting it, the agricultural and industrial sectors
Tautvydė Dorofėjūtė, Simona Paulikienė, Tomas Ūksas, Egidijus Zvicevičius, Kęstutis Žiūra, Kristina Lekavičienė   +5 more
doaj   +1 more source

No evidence for the presence of tissue factor in high‐purity preparations of immunologically isolated eosinophils [PDF]

, 2008
Mikhail A. Sovershaev, Klaus Lind, Hege Devold, T. JØRGENSEN, J.‐B. HANSEN, Bjarne Østerud, Elena M. Egorina   +6 more
openalex   +1 more source

Effect of horizontal position of fiber post placement on fracture resistance and location in endodontically treated premolars with a MOD preparation

, 2021
Marla Kneib Ferri, Simone Bonato Luisi, Luiz Henrique Burnett, Rafael Melara, Tiago André Fontoura de Melo   +4 more
openalex   +2 more sources

PYCR1 inhibition in bone marrow stromal cells enhances bortezomib sensitivity in multiple myeloma cells by altering their metabolism

Molecular Oncology, EarlyView.
This study investigated how PYCR1 inhibition in bone marrow stromal cells (BMSCs) indirectly affects multiple myeloma (MM) cell metabolism and viability. Culturing MM cells in conditioned medium from PYCR1‐silenced BMSCs impaired oxidative phosphorylation and increased sensitivity to bortezomib.
Inge Oudaert, Lauren van den Broecke, Osman Aksoy, Judith Lind, Sonia Vallet, Arne Van der Vreken, Gamze Ates, Ann Massie, Ken Maes, Kim De Veirman, Elke De Bruyne, Karin Vanderkerken, Klaus Podar, Eline Menu   +13 more
wiley   +1 more source

Cross-Linked Enzyme Aggregates of Feruloyl Esterase Preparations from Thermothelomyces thermophila and Talaromyces wortmannii [PDF]

, 2018
Anastasia Zerva, Io Antonopoulou, Josefine Enman, Laura Iancu, Ulrika Rova, Paul Christakopoulos   +5 more
openalex   +1 more source

Inhibition of CDK9 enhances AML cell death induced by combined venetoclax and azacitidine

Molecular Oncology, EarlyView.
The CDK9 inhibitor AZD4573 downregulates c‐MYC and MCL‐1 to induce death of cytarabine (AraC)‐resistant AML cells. This enhances VEN + AZA‐induced cell death significantly more than any combination of two of the three drugs in AraC‐resistant AML cells.
Shuangshuang Wu, Jianlei Zhao, Aaban Asfar Azmi, Avanti Gupte, Jenna Thibodeau, Shuang Liu, Jinli Yang, Guan Wang, Holly Edwards, Lisa A. Polin, Juiwanna Kushner, Sijana H. Dzinic, Kathryn White, Julie Boerner, Maik Hüttemann, Jay Yang, Yue Wang, Jeffrey W. Taub, Yubin Ge   +18 more
wiley   +1 more source