Forebrain Origins of Glutamatergic Innervation to the Rat Paraventricular Nucleus of the Hypothalamus: Differential Inputs to the Anterior Versus Posterior Subregions [PDF]
The hypothalamic paraventricular nucleus (PVN) regulates numerous homeostatic systems and functions largely under the influence of forebrain inputs. Glutamate is a major neurotransmitter in forebrain, and glutamate neurosignaling in the PVN is known to ...
Cullinan, William E +4 more
core +3 more sources
Neurobiology of the stress response early in life: evolution of a concept and the role of corticotropin releasing hormone. [PDF]
Over the last few decades, concepts regarding the presence of hormonal and molecular responses to stress during the first postnatal weeks in the rat and the role of the neuropeptide corticotropin releasing hormone (CRH) in these processes, have been ...
Avishai-Eliner, S +3 more
core +1 more source
Remifentanil post-conditioning attenuates cardiac ischemia-reperfusion injury via κ or δ opioid receptor activation [PDF]
Background: Ischemic pre- or post-conditioning of the heart has been shown to involve opioid receptors. Remifentanil, an ultra-short-acting selective μ opioid receptor agonist in clinical use, pre-conditions the rat heart against ischemia-reperfusion ...
Irwin, MG, Jiang, LL, Li, R, Wong, GTC
core +1 more source
Parvalbumin-neurons of the ventrolateral hypothalamic parvafox nucleus receive a glycinergic input: a gene-microarray study [PDF]
The ventrolateral hypothalamic parvafox (formerly called PV1-Foxb1) nucleus is an anatomical entity of recent discovery and unknown function. With a view to gaining an insight into its putative functional role(s), we conducted a gene-microarray ...
Albisetti, Gioele W. +2 more
core +1 more source
International audienceThe thalamic centromedian-parafascicular (CM/Pf) complex, mainly represented by Pf in rodents, is proposed as an interesting target for the neurosurgical treatment of movement disorders, including Parkinson's disease. In this study,
Jouve, Loréline +3 more
core +4 more sources
Intrathecal Long-Term Gene Expression by Self-Complementary Adeno-Associated Virus type 1 Suitable for Chronic Pain Studies in Rats [PDF]
BackgroundIntrathecal (IT) gene transfer is an attractive approach for targeting spinal mechanisms of nociception but the duration of gene expression achieved by reported methods is short (up to two weeks) impairing their utility in the chronic pain ...
Benjamin Storek +8 more
core +2 more sources
Striatal input from the ventrobasal complex of the rat thalamus [PDF]
We have analyzed whether caudal regions of the caudate putamen receive direct projections from thalamic sensory relay nuclei such as the ventrobasal complex.
Arribas, J. (J.) +3 more
core
Molecular mechanisms underlying increased PDYN and dynorphin expression in the prefrontal cortex of alcoholic men [PDF]
Alcohol dependence is a chronic relapsing disorder caused by drug x gene x environment interactions for which pharmacotherapy is but moderately effective.
Henriksson, Richard
core +1 more source
Enfermedad de Huntington: estado del arte [PDF]
La enfermedad de Huntington es un desorden monogenético autosómico dominante, que genera un trastorno neurodegenerativo caracterizado por la pérdida de neuronas en diferentes partes del cerebro.
Rodas Sepúlveda, Carlos Daniel +1 more
core
Aldosterone increases T-type calcium channel expression and in vitro beating frequency in neonatal rat cardiomyocytes [PDF]
Objective: Although aldosterone has been implicated in the pathogenesis of cardiac hypertrophy and heart failure, its cellular mechanism of action on cardiomyocyte function is not yet completely elucidated.
Barrère-Lemaire, Stéphanie +6 more
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