Results 81 to 90 of about 2,094 (191)

Cells expressing preproenkephalin mRNA in the rat pineal gland are not serotonin-producing pinealocytes: evidence using in situ hybridization combined with immunocytochemistry for serotonin

, 1996
1. Preproenkephalin (PPEnk) mRNA expressing cells have been identified in rat pineal gland using radioactive in situ hybridization histochemistry. 2. Approximately 7% of the cells in the pineal gland (7.5 +/- 0.86, mean +/- 95% CI) express PPEnk mRNA ...
Sagen, J, Pappas, G D, Wang, X T, Unnerstall, J R   +3 more
core   +1 more source

The effect of aging on the response of striatal preproenkephalin and preprotachykinin mRNA contents to chronic haloperidol treatment in rats: Measurement by solution-hybridization RNase protection assay

, 1998
The preproenkephalin (PPeK) and preprotachykinin (PPT) mRNA contents in 3-, 10- and 23-month-old rats in the striatum were measured by solution hybridization-RNase protection assay after 3 weeks of haloperidol injection.
Tang, F, Lau, SM
core   +1 more source

Aberrant methylation of preproenkephalin and p16 genes in pancreatic Intraepithelial neoplasia and pancreatic ductal adenocarcinoma

, 2002
Pancreatic intraductal neoplasia (PanIN) is thought to be the precursor to infiltrating pancreatic ductal adenocarcinoma. We have previously shown that the preproenkephalin (ppENK) and p16 genes are aberrantly methylated in pancreatic adenocarcinoma.
Takashi Ueki, Goggins, M., Walter, K. M., Robb E. Wilentz, Kimberly M. Walter, Ralph H. Hruban, Rosty, C., Charles J. Yeo, Ueki, T., Noriyoshi Fukushima, Hruban, R. H., Christophe Rosty, Sato, N., Fukushima, N., Michael Goggins, Wilentz, R. E., Yeo, C. J., Norihiro Sato   +17 more
core   +1 more source

Immunohistochemical detection of preproenkephalin in the mouse brain [PDF]

Protocol Exchange, 2013
Liliana Minichiello, Dario Besusso, Mirjam Geibel, Liliana Minichiello   +3 more
openaire   +1 more source

Preproenkephalin Expression in Peripheral Blood Mononuclear Cells of Acutely Underweight and Recovered Patients with Anorexia Nervosa

, 2010
<i>Background:</i> The prohormone preproenkephalin (ppE) and its derived peptides are involved in leukocyte functioning as well as in the regulation of hunger and satiety.
Roland Burghardt, Ernst Pfeiffer, Carmen Infante-Duarte, Ulrike Lehmkuhl, Stefan Ehrlich, Deike Weiss, Harriet Salbach-Andrae, Isabell Hamann   +7 more
core   +1 more source

Crosstalk between oestrogen receptors and thyroid hormone receptor isoforms results in differential regulation of the preproenkephalin gene

, 2001
Nuclear receptors are ligand-activated transcription factors, which have the potential to integrate internal metabolic events in an organism, with consequences for control of behaviour.
Daniel, S., Chin, W. W., S. Daniel, D. Pfaff, Zhu, Y. S., Y.‐S. Zhu, Koibuchi, N., W. W. Chin, Vasudevan, Nandini, Pfaff, D., N. Vasudevan, N. Koibuchi   +11 more
core   +1 more source

Overexpression of µ-Opioid Receptors in Peripheral Afferents, but Not in Combination with Enkephalin, Decreases Neuropathic Pain Behavior and Enhances Opioid Analgesia in Mouse

, 2018
Background The current study used recombinant herpes simplex virus type I to increase expression of µ-opiate receptors and the opioid ligand preproenkephalin in peripheral nerve fibers in a mouse model of neuropathic pain.
Brad Peper, Amanda H. Klein, Steven P. Wilson, Sarah Sweitzer, Matthias Ringkamp, Husam K. Mohammad, Srinivasa N. Raja, Rabiah Ali   +7 more
core   +1 more source

Immunohistochemical evidence for preproenkephalin A synthesis in human retinoblastoma.

Investigative ophthalmology & visual science, 1984
Human retinoblastoma contains clusters of cells immunoreactive for methionine-enkephalin and methionine-enkephalin-arginine-phenylalanine. Some tumour cells also exhibited methionine-enkephalin-arginine-glycine-leucine-like immunoreactivity. The results are in agreement with those obtained with similar testing of neuroblastoma cell cultures.
A, Tarkkanen, T, Tervo, K, Tervo, P, Panula   +3 more
openaire   +1 more source

Striatal Responses to Partial Dopaminergic Lesion: Evidence for Compensatory Sprouting

, 2000
Dopaminergic lesions result in the acute loss of striatal dopamine content, the loss of tyrosine hydroxylase-immunoreactive fibers, upregulation of preproenkephalin mRNA expression, and compensatory changes in the synthesis and metabolism of dopamine ...
David D. Song, Suzanne N. Haber
core   +1 more source

Editorial: Physiology and pathophysiology of the olfactory system. [PDF]

Front Neural Circuits, 2022
Kashiwadani H, Heinbockel T, Imamura F, Yamaguchi M, Koyama S, Kondo K.   +5 more
europepmc   +1 more source