Results 151 to 160 of about 3,085 (184)

Preproenkephalin A-derived opioid peptides and mRNA of preproenkephalin A in human pheochromocytomas

Molecular and Cellular Endocrinology, 1987
Tissue contents of immunoreactive met-enkephalin (Met-Enk), leu-enkephalin (Leu-Enk) and met-enkephalin-Arg-Gly-Leu (Met-Enk-AGL) were determined by specific RIAs in 17 pheochromocytomas and the levels of preproenkephalin A mRNA were compared in some of these tissues by Northern blot hybridization.
T, Yanase   +4 more
openaire   +2 more sources

Dopaminergic modulation of pallidal preproenkephalin mRNA

Molecular Brain Research, 1999
The present study examines dopaminergic regulation of neuropeptide gene expression within a relatively poorly characterized population of cells, the preproenkephalin (PPE) mRNA containing neurons of the globus pallidus (GP). Rats that received 6-hydroxydopamine (6-OHDA) lesions or repeated D1 or D2 antagonist administration were compared to control ...
J J, Schuller   +2 more
openaire   +2 more sources

Critical role of preproenkephalin in experimental autoimmune encephalomyelitis

Journal of Neuroimmunology, 2006
Experimental autoimmune encephalomyelitis (EAE) is an organ-specific autoimmune disease model used to investigate mechanisms involved in the activation of self-reactive T cells. Preproenkephalin (PPNK) is the gene that encodes the protein proenkephalin A that has been detected in the brain, adrenal cells and cells of the immune system.
Catherine, Weir   +6 more
openaire   +4 more sources

Effect of Lactation on Hypothalamic Preproenkephalin Gene Expression

Journal of Neuroendocrinology, 1995
AbstractEnkephalin appears to modulate several aspects of reproductive function in female rats. The purpose of this study was to determine if lactation influences preproenkephalin gene expression in one or more hypothalamic nuclei known to be involved in maternal or reproductive behavior and prolactin secretion. Lactating rats were killed on day 3 (LAC
M A, Ottinger   +4 more
openaire   +2 more sources

Preproenkephalin mRNA-expressing neurones in the rat thalamus

NeuroReport, 1995
We investigated the expression of preproenkephalin mRNA in the rat thalamus by in situ hybridization histochemistry using a radiolabelled full-length cRNA probe. Enkephalinergic neurones were present in the ventral thalamus, epithalamus, and intralaminar and midline nuclei of the dorsal thalamus.
O, Hermanson, M, Hallbeck, A, Blomqvist
openaire   +2 more sources

Preproenkephalin B-derived opioid peptides in human phaeochromocytomas

Acta Endocrinologica, 1987
Abstract. We demonstrated the presence and the secretion in vivo and in vitro of immunoreactive preproenkephalin B-derived opioid peptides (α-neoendorphin, dynorphin and leumorphin) in human phaeochromocytomas. In senventeen human phaeochromocytomas and two human adrenal medullas, the tissue contents of immunoreactive preproenkephalin B-derived opioid ...
T, Yanase   +3 more
openaire   +2 more sources

Th2-dependent airway eosinophilia is regulated by preproenkephalin

Journal of Neuroimmunology, 2000
We have used preproenkephalin (PPNK)-deficient mice to study the role of PPNK in the development of airway inflammation. Airway eosinophilia was established by either sensitization followed by airway challenge with OVA or by infection with Nippostrongylus brasiliensis.
S, Hook   +6 more
openaire   +2 more sources

Region-specific regulation of preproenkephalin mRNA in cultured astrocytes

Molecular Brain Research, 1991
Regulation of preproenkephalin (PPE) mRNA was examined in astrocytes cultured from several regions of the neonatal rat brain. Astrocytes from these regions expressed differing levels of PPE mRNA, with higher levels in astrocytes from the hypothalamus followed by frontal cortex and striatum.
D K, Batter, J A, Kessler
openaire   +2 more sources

Preproenkephalin A Gene Expression in Rat Pineal

Neuroendocrinology, 1991
Preproenkephalin A (ppEnk) mRNA has been identified in extracts of rat pineal gland using oligonucleotides complementary to nonoverlapping regions of this mRNA. The mRNA has an apparent molecular size of 1.4 kb, equivalent to that found in rat brain.
openaire   +2 more sources

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