Results 151 to 160 of about 2,309 (192)

Preproenkephalin mRNA-expressing neurones in the rat thalamus

NeuroReport, 1995
We investigated the expression of preproenkephalin mRNA in the rat thalamus by in situ hybridization histochemistry using a radiolabelled full-length cRNA probe. Enkephalinergic neurones were present in the ventral thalamus, epithalamus, and intralaminar and midline nuclei of the dorsal thalamus.
O, Hermanson, M, Hallbeck, A, Blomqvist
openaire   +2 more sources

Cloning and Sequence Analysis of cDNA for Bovine Adrenal Preproenkephalin

Nature, 1982
The nucleotide sequence of cloned cDNA for preproenkephalin from bovine adrenal medulla indicates that the precursor protein contains four copies of Met-enkephalin and one copy each of Leu-enkephalin, Met-enkephalin-Arg6-Phe7 and Met-enkephalin-Arg6-Gly7-Leu8, a previously undetected opioid peptide.
Masaharu Noda, Shosaku Numa, Seiichi Inayama   +2 more
exaly   +3 more sources

Ontogeny of preproenkephalin mRNA expression in the rat retina

Visual Neuroscience, 1996
AbstractEndogenous opioid systems (i.e. opioid peptides and opioid receptors) modulate developmental events in the neonatal mammalian retina. In the present study, the mRNA encoding preproenkephalin A (PPE), the prohormone for the opioid growth factor (OGF), [Met5]-enkephalin, was studied in the developing and the adult retinas of rats.
T, Isayama, P J, McLaughlin, I S, Zagon
openaire   +2 more sources

Preproenkephalin mRNA in T-Cells, Macrophages, and Mast Cells

Journal of Neuroscience Research, 1987
AbstractThe presence of preproenkephaline mRNA in tumor cell lines derived from myeloid and mast cells was analyzed by RNA dot blot hybridization. A B‐cell lymphoma was negative for preproenkephalin mRNA, but several T‐cell lymphomas were positive.
Judith M Martin, M B Prystowsky, R H Angeletti   +2 more
exaly   +3 more sources

Localization of preproenkephalin a mRNA in the neonatal rat retina

Brain Research Bulletin, 1991
An opioid growth factor, [Met5]-enkephalin, is known to regulate developmental events in the neonatal rat retina. This growth factor interacts with the zeta (zeta) opioid receptor to modulate retinal ontogeny. Both peptide and receptor are present in developing retina, but not in adult retina.
T, Isayama, I S, Zagon
openaire   +2 more sources

Molecular Cloning and Characterization of the Hamster Preproenkephalin A cDNA

DNA and Cell Biology, 1994
The cDNA for hamster preproenkephalin A (ENK) was cloned from an adrenal gland cDNA library constructed in the lambda ZapII vector. A nearly full-length cDNA was obtained and its 5' end region was completed using the technique of rapid amplification of cDNA ends (RACE).
M, Beaulieu, M, Ouellette, L, Desgroseillers, L, Brakier-Gingras   +3 more
openaire   +2 more sources

Expression of the preproenkephalin A gene in the heart of cardiomyopathic hamsters

Biochemistry and Cell Biology, 1991
The expression of the preproenkephalin A gene (Enk gene), which codes for the precursor of enkephalins, was investigated in the heart of hamsters with a hereditary cardiomyopathy at four different stages of the disease: the prenecrotic stage (30 days), the necrotic stage (60 days), the hypertrophic stage (120 days), and the final stage (200 days).
M, Ouellette, M, Dumont, S, Lemaire, L, Brakier-Gingras   +3 more
openaire   +2 more sources

Th2-dependent airway eosinophilia is regulated by preproenkephalin

Journal of Neuroimmunology, 2000
We have used preproenkephalin (PPNK)-deficient mice to study the role of PPNK in the development of airway inflammation. Airway eosinophilia was established by either sensitization followed by airway challenge with OVA or by infection with Nippostrongylus brasiliensis.
S, Hook, M, Prout, M, Camberis, M, Konig, A, Zimmer, G, Van Heeke, G, Le Gros   +6 more
openaire   +2 more sources

Preproenkephalin A Gene Expression in Rat Pineal

Neuroendocrinology, 2008
Preproenkephalin A (ppEnk) mRNA has been identified in extracts of rat pineal gland using oligonucleotides complementary to nonoverlapping regions of this mRNA. The mRNA has an apparent molecular size of 1.4 kb, equivalent to that found in rat brain.
openaire   +2 more sources

Inducible preproenkephalin DNA binding proteins in the rat striatum

Molecular and Cellular Neuroscience, 1991
The molecular manifestation of whole animal and cellular adaptive responses results from stimulus-secretion-synthesis coupling to selected genes. Effects are mediated through receptor-linked, signal-transduction pathways involving trans-acting nuclear proteins binding to cis-acting DNA regulatory elements. In the current report we have identified those
E F, La Gamma, G, Weisinger
openaire   +2 more sources