Reduced Prepulse Inhibition as a Biomarker of Schizophrenia [PDF]
Frontiers in Behavioral Neuroscience, 2016 The startle response is composed by a set of reflex behaviors intended to prepare the organism to face a potentially relevant stimulus. This response can be modulated by several factors as, for example, repeated presentations of the stimulus (startle ...
Luis Gonzalo De La Casa +5 more
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Prepulse inhibition of acoustic startle reflex as a function of the frequency difference between prepulse and background sounds in mice. [PDF]
PLoS ONE, 2012 Prepulse inhibition (PPI) depicts the effects of a weak sound preceding strong acoustic stimulus on acoustic startle response (ASR). Previous studies suggest that PPI is influenced by physical parameters of prepulse sound such as intensity and preceding ...
Sidhesh Basavaraj, Jun Yan
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Reflex Excitability Regulates Prepulse Inhibition [PDF]
The Journal of Neuroscience, 2000 Presentation of a weak stimulus, a prepulse, before a reflex-evoking stimulus decreases the amplitude of the reflex response relative to reflex amplitude evoked without a preceding prepulse.
Kavita R. Peshori +4 more
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Journal of Parkinson’s Disease, 2014 Background: Prepulse inhibition is a measure of sensorimotor gating, which reflects the ability to filter or ‘gate’ irrelevant information. Prepulse inhibition is dramatically altered in basal ganglia disorders associated with dysfunction in the midbrain
Marielle Zoetmulder +5 more
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Prepulse inhibition of auditory change-related cortical responses
BMC Neuroscience, 2012 Background Prepulse inhibition (PPI) of the startle response is an important tool to investigate the biology of schizophrenia. PPI is usually observed by use of a startle reflex such as blinking following an intense sound.
Inui Koji +7 more
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GABAergic mechanisms involved in the prepulse inhibition of auditory evoked cortical responses in humans. [PDF]
PLoS ONE, 2018 Despite their essential roles in signal processing in the brain, the functions of interneurons currently remain unclear in humans. We recently developed a method using the prepulse inhibition of sensory evoked cortical responses for functional ...
Koji Inui +4 more
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The Effects of Brief Mindfulness Training on Attentional Processes: Mindfulness Increases Prepulse Facilitation but Not Prepulse Inhibition [PDF]
Frontiers in Psychology, 2021 Mindfulness is intentional focus of one’s attention on emotions, thoughts, or sensations occurring in the present moment with a nonjudgmental attitude.
Ole Åsli +2 more
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A Cellular Mechanism for Prepulse Inhibition [PDF]
Neuron, 2003 In prepulse inhibition (PPI), startle responses to sudden, unexpected stimuli are markedly attenuated if immediately preceded by a weak stimulus of almost any modality.
Tian, Li-Ming +9 more
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The effect of repeated prepulse and reflex stimulus presentations on startle prepulse inhibition
Biological Psychology, 1998 The magnitude of a startle reflex is inhibited if the reflex-eliciting stimuli is preceded by a prepulse stimulus at a short lead interval. Previous research in humans has shown that the extent of prepulse inhibition decreases over repeated presentations
Krinitzky, SP +3 more
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Prepulse inhibition in Drosophila melanogaster larvae [PDF]
Biology Open, 2018 The neural mechanisms of psychiatric diseases like autism spectrum disorder and schizophrenia have been intensively studied, and a number of candidate genes have been identified.
Yutaro Matsumoto +9 more
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