Results 31 to 40 of about 990,733 (166)

Schizophrenia-like behavior is not altered by melatonin supplementation in rodents [PDF]

Anais da Academia Brasileira de Ciências, 2020
An emerging area in schizophrenia research focuses on the impact of immunomodulatory drugs such as melatonin, which have played important roles in many biological systems and functions, and appears to be promising.
ARLINDO C. AFONSO, FELIPE D. PACHECO, LARA CANEVER, PATRICIA G. WESSLER, GUSTAVO A. MASTELLA, AMANDA K. GODOI, ISABELA HUBBE, LAURA M. BISCHOFF, ALEX VICTOR S. BIALECKI, ALEXANDRA I. ZUGNO   +9 more
doaj   +2 more sources

The effect of repeated prepulse and reflex stimulus presentations on startle prepulse inhibition

, 1998
The magnitude of a startle reflex is inhibited if the reflex-eliciting stimuli is preceded by a prepulse stimulus at a short lead interval. Previous research in humans has shown that the extent of prepulse inhibition decreases over repeated presentations
Krinitzky, SP, Steven P Krinitzky, Lipp, OV, Ottmar V Lipp   +3 more
core   +1 more source

Gating of auditory evoked potentials and prepulse inhibition - Webs.pdf

, 2022
GATING OF AUDITORY EVOKED POTENTIALS AND PREPULSE INHIBITION: AN ANIMAL MODELING APPROACH DISTINCT RODENT GENOTYPES AND 
Natasja de Bruin (13769668)
core   +1 more source

The Potential Role of Serotonin1A Receptors in Post-weaning Social Isolation–Induced Abnormal Behaviors in Rodents

Journal of Pharmacological Sciences, 2014
.: Post-weaning social isolation in mice induces behavioral abnormalities such as hyperactivity, aggression, depression- and anxiety-like behaviors, deficits of prepulse inhibition, and reduced pain sensitivity to the noxious stimuli. Then, this mouse is
Yukio Ago, Kazuhiro Takuma, Toshio Matsuda   +2 more
doaj   +1 more source

New paradigm for auditory paired pulse suppression.

PLoS ONE, 2017
Sensory gating is a mechanism of sensory processing used to prevent an overflow of irrelevant information, with some indexes, such as prepulse inhibition (PPI) and P50 suppression, often utilized for its evaluation.
Nobuyuki Takeuchi, Shunsuke Sugiyama, Koji Inui, Kousuke Kanemoto, Makoto Nishihara   +4 more
doaj   +1 more source

Motor-coordination-dependent learning, more than others, is impaired in transgenic mice expressing pseudorabies virus immediate-early protein IE180. [PDF]

PLoS ONE, 2010
The cerebellum in transgenic mice expressing pseudorabies virus immediate-early protein IE180 (TgIE96) was substantially diminished in size, and its histoarchitecture was severely disorganized, resulting in severe ataxia.
Juan C López-Ramos, Yukiko Tomioka, Masami Morimatsu, Sayo Yamamoto, Kinuyo Ozaki, Etsuro Ono, José M Delgado-García   +6 more
doaj   +1 more source

Signal detection and characterisation of a novel drug–drug interaction between methadone and a synthetic cannabinoid receptor agonist

British Journal of Pharmacology, EarlyView.
Background and Purpose Little is known about how synthetic cannabinoid receptor agonist (SCRA) co‐use with other psychoactive substances may exacerbate risk of death. This study aimed to characterise the polypharmacy of deaths where SCRAs were detected at post‐mortem, investigate the cardiotoxicity of SCRAs and probe their inhibition of human ether‐a ...
Kirsten L. Rock, Louise M. Hesketh, Hongwei Cheng, Shuoqi Chen, Simon Hudson, Graeme Henderson, Jules C. Hancox, Michael J. Shattock, Michael J. Curtis, Caroline S. Copeland   +9 more
wiley   +1 more source

Prepulse reactivity in prepulse inhibition. [PDF]

, 2010
Prepulse inhibition (PPI) is a popular paradigm in sensorimotor gating research. In healthy individuals the weak lead stimulus (i.e., the prepulse) presentation results in a reduction in the startle probe (pulse) elicited response. The motor responses to
Ewa G Truchanowicz
core  

Effect of age on the gap-prepulse inhibition of the cortical N1-P2 complex in humans as a step towards an objective measure of tinnitus.

PLoS ONE, 2020
The gap-prepulse inhibition of the acoustic startle reflex has been widely used as a behavioral method for tinnitus screening in animal studies. The cortical-evoked potential gap-induced inhibition has also been investigated in animals as well as in ...
Yunseo Ku, Do Youn Kim, Chiheon Kwon, Tae Soo Noh, Moo Kyun Park, Jun Ho Lee, Seung Ha Oh, Hee Chan Kim, Myung-Whan Suh   +8 more
doaj   +1 more source

Evidence of Hyperacusis in Adult Rats Following Non-traumatic Sound Exposure

Frontiers in Systems Neuroscience, 2019
Manipulations that enhance neuroplasticity may inadvertently create opportunities for maladaptation. We have previously used passive exposures to non-traumatic white noise to open windows of plasticity in the adult rat auditory cortex and induce ...
Maryse E. Thomas, Maryse E. Thomas, Gerson D. Guercio, Gerson D. Guercio, Kristina M. Drudik, Étienne de Villers-Sidani, Étienne de Villers-Sidani   +6 more
doaj   +1 more source