Results 41 to 50 of about 12,508 (203)

Sensorimotor gating and clinical outcome following cognitive behaviour therapy for psychosis

, 2012
Background: Prepulse inhibition (PPI) of the startle response refers to the ability of a weak prestimulus to transiently inhibit the response to a closely following strong sensory stimulus.
Peters, Emmanuelle R., Emmanuelle R. Peters, Peters, Emmanuelle R.; id_orcid, Antonova, Elena, Preethi Premkumar, Kuipers, Elizabeth; id_orcid, Satya Raghuvanshi, Aasen, I, Kumari, V, Antonova, E, Ingrid Aasen, Kuipers, Elizabeth, Elizabeth Kuipers, Elena Antonova, Aasen, Ingrid, Premkumar, P, Anilkumar, AP, Kuipers, E, Anilkumar, Anantha P., Peters, ER, Veena Kumari, Fannon, D, Raghuvanshi, Satya, Kumari, Veena, Anantha P. Anilkumar, Dominic Fannon, Raghuvanshi, S, Fannon, Dominic, Premkumar, Preethi   +28 more
core   +1 more source

Prepulse inhibition of startle.

, 2013
Behavioral tests in mouse exposed to maternal immune activation at gestation day 9 or 17 (GD9 POL; GD17 POL) compared to controls (CON). Prepulse inhibition of startle (PPI). % PPI =  (pulse-alone - prepulse-plus-pulse)/pulse-alone×100%.
Sookja Chung (261115), Ed X. Wu (285920), Urs Meyer (356164), Qi Li (67548), Edward S. Hui (371469), Siew E. Chua (350156), Grainne M. McAlonan (285918), Ran Wei (295560), Pak C. Sham (58020), Charlton Cheung (350151), Joram Feldon (356165)   +10 more
core   +1 more source

Habituation and Prepulse Inhibition of Acoustic Startle in Rodents [PDF]

Journal of Visualized Experiments, 2011
The acoustic startle response is a protective response, elicited by a sudden and intense acoustic stimulus. Facial and skeletal muscles are activated within a few milliseconds, leading to a whole body flinch in rodents(1). Although startle responses are reflexive responses that can be reliably elicited, they are not stereotypic.
Valsamis, Bridget, Schmid, Susanne
openaire   +4 more sources

A QTL on rat chromosome 7 modulates prepulse inhibition, a neuro-behavioral trait of ADHD, in a Lewis x SHR intercross

Behavioral and Brain Functions, 2006
Background Attention deficit hyperactivity disorder (ADHD) is a complex neuropsychiatric disorder with a substantial genetic component. The Spontaneously Hypertensive Rats (SHR), considered as a good animal model of ADHD, also show less anxiety-like ...
Ramos André, Raba Frantz, Terenina-Rigaldie Elena, Vendruscolo Leandro, Takahashi Reinaldo, Mormède Pierre   +5 more
doaj   +1 more source

Schizophrenia-like behavior is not altered by melatonin supplementation in rodents [PDF]

Anais da Academia Brasileira de Ciências, 2020
An emerging area in schizophrenia research focuses on the impact of immunomodulatory drugs such as melatonin, which have played important roles in many biological systems and functions, and appears to be promising.
ARLINDO C. AFONSO, FELIPE D. PACHECO, LARA CANEVER, PATRICIA G. WESSLER, GUSTAVO A. MASTELLA, AMANDA K. GODOI, ISABELA HUBBE, LAURA M. BISCHOFF, ALEX VICTOR S. BIALECKI, ALEXANDRA I. ZUGNO   +9 more
doaj   +2 more sources

The effects of kappa-opioid receptor ligands on prepulse inhibition and CRF-induced prepulse inhibition deficits in the rat [PDF]

Psychopharmacology, 2010
Kappa-opioid receptor (KOR) agonists produce dysphoria and psychotomimesis in humans. KORs are enriched in the prefrontal cortex and other brain regions that regulate mood and cognitive function. Dysregulation of the dynorphin/KOR system has been implicated in the pathogenesis of schizophrenia, depression, and bipolar disorder.
Hugo A, Tejeda, Vladimir I, Chefer, Agustin, Zapata, Toni S, Shippenberg   +3 more
openaire   +2 more sources

The Potential Role of Serotonin1A Receptors in Post-weaning Social Isolation–Induced Abnormal Behaviors in Rodents

Journal of Pharmacological Sciences, 2014
.: Post-weaning social isolation in mice induces behavioral abnormalities such as hyperactivity, aggression, depression- and anxiety-like behaviors, deficits of prepulse inhibition, and reduced pain sensitivity to the noxious stimuli. Then, this mouse is
Yukio Ago, Kazuhiro Takuma, Toshio Matsuda   +2 more
doaj   +1 more source

New paradigm for auditory paired pulse suppression.

PLoS ONE, 2017
Sensory gating is a mechanism of sensory processing used to prevent an overflow of irrelevant information, with some indexes, such as prepulse inhibition (PPI) and P50 suppression, often utilized for its evaluation.
Nobuyuki Takeuchi, Shunsuke Sugiyama, Koji Inui, Kousuke Kanemoto, Makoto Nishihara   +4 more
doaj   +1 more source

Motor-coordination-dependent learning, more than others, is impaired in transgenic mice expressing pseudorabies virus immediate-early protein IE180. [PDF]

PLoS ONE, 2010
The cerebellum in transgenic mice expressing pseudorabies virus immediate-early protein IE180 (TgIE96) was substantially diminished in size, and its histoarchitecture was severely disorganized, resulting in severe ataxia.
Juan C López-Ramos, Yukiko Tomioka, Masami Morimatsu, Sayo Yamamoto, Kinuyo Ozaki, Etsuro Ono, José M Delgado-García   +6 more
doaj   +1 more source

Lymphatic Abnormalities in Noonan Syndrome Extend Beyond Clinically Apparent Disease

American Journal of Medical Genetics Part A, EarlyView.
ABSTRACT Lymphatic disease represents a well‐described manifestation of Noonan syndrome (NS), yet the full phenotypic spectrum remains incompletely characterized, especially in asymptomatic individuals. We conducted a cross‐sectional study including 10 individuals with NS (four with peripheral lymphedema and six without) and 10 age‐ and sex‐matched ...
Inger Norlyk Sheyanth, Benjamin Kelly, Sheyanth Mohanakumar, Steffen Ringgaard, Yoav Dori, Irene Kibæk Nielsen, Uffe Birk Jensen, Vibeke Elisabeth Hjortdal   +7 more
wiley   +1 more source