Transcriptomic analysis reveals the function of m6A regulators in aged cochlea [PDF]
Objective: Presbycusis is a prevalent health issue among the elderly. Previous studies have shown mechanisms related to this condition, but the underlying mechanisms of presbycusis remain elusive.
Yanbing Lai+6 more
doaj +2 more sources
Biochemical considerations in presbycusis [PDF]
Virtually no direct information about biochemical changes in the peripheral auditory system due to aging is available. However, numerous predictions about biochemical changes due to characteristic degeneration patterns can be made indirectly. (1) Since glycogen and calmodulin are extremely high in outer hair cells, significant degeneration of these ...
Isolde Thalmann+2 more
openaire +3 more sources
Presbycusis: Pathology, Signal Pathways, and Therapeutic Strategy
In ARHL, the stria vascularis, acting as a cochlear battery, gradually loses its ability to maintain the endocochlear potential, leading to impaired hair cell function and progressive hearing loss. Single‐cell sequencing reveals age‐related cellular changes in the cochlea, providing insights into the underlying mechanisms of aging and potential ...
Xiaoxu Zhao+12 more
openalex +2 more sources
Association of genetic variations in the mitochondrial DNA control region with presbycusis
Masoumeh Falah,1 Mohammad Farhadi,1 Seyed Kamran Kamrava,1 Saeid Mahmoudian,1 Ahmad Daneshi,1 Maryam Balali,1 Alimohamad Asghari,2 Massoud Houshmand1,3 1ENT and Head & Neck Research Center and Department, Iran University of Medical Sciences, Tehran,
Falah M+7 more
doaj +2 more sources
Alterations of Excitation-Inhibition Balance and Brain Network Dynamics Support Sensory Deprivation Theory in Presbycusis. [PDF]
Su M+9 more
europepmc +2 more sources
Clinicopathological Approach to Presbycusis
Kazumi Makishima
openaire +4 more sources
Effects of neurofeedback training on the alpha activity in quantitative electroencephalography, cognitive function, and speech perception in elderly with presbycusis: a quasi-experimental study. [PDF]
Kim HJ, Weon HW, Son HK.
europepmc +3 more sources
Mendelian non-syndromic and syndromic hearing loss genes contribute to presbycusis. [PDF]
Cornejo-Sanchez DM+6 more
europepmc +2 more sources
Anodal direct current stimulation of the auditory cortex at the onset of presbycusis delays cortical aging. [PDF]
Fernández Del Campo IS+4 more
europepmc +2 more sources
Reorganized Brain Functional Network Topology in Presbycusis
PurposePresbycusis is characterized by bilateral sensorineural hearing loss at high frequencies and is often accompanied by cognitive decline. This study aimed to identify the topological reorganization of brain functional network in presbycusis with ...
Bing Guan+8 more
doaj +1 more source