Results 11 to 20 of about 7,911 (239)

Transcriptomic analysis reveals the function of m6A regulators in aged cochlea [PDF]

open access: yesBrazilian Journal of Otorhinolaryngology
Objective: Presbycusis is a prevalent health issue among the elderly. Previous studies have shown mechanisms related to this condition, but the underlying mechanisms of presbycusis remain elusive.
Yanbing Lai   +6 more
doaj   +2 more sources

Biochemical considerations in presbycusis [PDF]

open access: bronzeThe Journal of the Acoustical Society of America, 1988
Virtually no direct information about biochemical changes in the peripheral auditory system due to aging is available. However, numerous predictions about biochemical changes due to characteristic degeneration patterns can be made indirectly. (1) Since glycogen and calmodulin are extremely high in outer hair cells, significant degeneration of these ...
Isolde Thalmann   +2 more
openaire   +3 more sources

Presbycusis: Pathology, Signal Pathways, and Therapeutic Strategy

open access: goldAdvanced Science, EarlyView.
In ARHL, the stria vascularis, acting as a cochlear battery, gradually loses its ability to maintain the endocochlear potential, leading to impaired hair cell function and progressive hearing loss. Single‐cell sequencing reveals age‐related cellular changes in the cochlea, providing insights into the underlying mechanisms of aging and potential ...
Xiaoxu Zhao   +12 more
openalex   +2 more sources

Association of genetic variations in the mitochondrial DNA control region with presbycusis

open access: greenClinical Interventions in Aging, 2017
Masoumeh Falah,1 Mohammad Farhadi,1 Seyed Kamran Kamrava,1 Saeid Mahmoudian,1 Ahmad Daneshi,1 Maryam Balali,1 Alimohamad Asghari,2 Massoud Houshmand1,3 1ENT and Head & Neck Research Center and Department, Iran University of Medical Sciences, Tehran,
Falah M   +7 more
doaj   +2 more sources

Mendelian non-syndromic and syndromic hearing loss genes contribute to presbycusis. [PDF]

open access: hybridEur J Hum Genet
Cornejo-Sanchez DM   +6 more
europepmc   +2 more sources

Anodal direct current stimulation of the auditory cortex at the onset of presbycusis delays cortical aging. [PDF]

open access: hybridBrain Struct Funct
Fernández Del Campo IS   +4 more
europepmc   +2 more sources

Reorganized Brain Functional Network Topology in Presbycusis

open access: yesFrontiers in Aging Neuroscience, 2022
PurposePresbycusis is characterized by bilateral sensorineural hearing loss at high frequencies and is often accompanied by cognitive decline. This study aimed to identify the topological reorganization of brain functional network in presbycusis with ...
Bing Guan   +8 more
doaj   +1 more source

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