Results 71 to 80 of about 10,634 (211)

Relación entre el déficit sensorial auditivo y depresión en personas mayores: revisión de la literatura [PDF]

, 2010
[Resumen] Los avances en las condiciones sanitarias y socioeconómicas de los países desarrollados han incrementado la esperanza de vida y el número de personas mayores. Sin embargo, aunque las condiciones sanitarias han mejorado, las alteraciones de la
García-Monasterio, Isabel, Maseda, Ana, Millán-Calenti, José Carlos, Rochette, Sophie   +3 more
core   +2 more sources

Chronic Low‐Level Lead Exposure Causes Auditory Impairment and Accelerates the Progression of Age‐Related Hearing Loss in C57BL/6J Mice

Aging Cell, Volume 25, Issue 1, January 2026.
Chronic low‐concentration lead exposure accelerates the development of ARHL. Lead exposure mediates damage to cochlear sensory cells via the mitochondrial protease LONP1, leading to irreversible hearing loss. ABSTRACT Heavy metal ion exposure has become a global public health concern.
Xue Bai, Li‐Hua Cheng, Zhi‐Bin Zhou, Kai‐Lang Zhou, Yan‐Peng Fu, Bing Liao, Mei‐Qun Wang, Xu‐Bo Chen, Hong‐Ping Chen, Yue‐Hui Liu, Kai Xu   +10 more
wiley   +1 more source

Association of genetic variations in the mitochondrial DNA control region with presbycusis

Clinical Interventions in Aging, 2017
Masoumeh Falah,1 Mohammad Farhadi,1 Seyed Kamran Kamrava,1 Saeid Mahmoudian,1 Ahmad Daneshi,1 Maryam Balali,1 Alimohamad Asghari,2 Massoud Houshmand1,3 1ENT and Head & Neck Research Center and Department, Iran University of Medical Sciences, Tehran,
Falah M, Farhadi M, Kamrava SK, Mahmoudian S, Daneshi A, Balali M, Asghari A, Houshmand M   +7 more
doaj  

Downregulation of BST2 Rescues Cochlear Nerve Demyelination in Age‐Related Hearing Loss via Enhancing Schwann Cell Migration

Aging Cell, Volume 25, Issue 1, January 2026.
The illustration indicates that increased BST2 expression in Schwann cells leads to cochlear nerve demyelination, accelerating hearing loss in ARHL. The upregulation of BST2 reduces POU6F1 expression by activating the NF‐κB pathway, which impairs MPZ transcription and Schwann cell migration, ultimately contributing to neural demyelination in ARHL ...
Mengxiao Liu, Qi Li, Huan Cao, Huan Yin, Jianwang Yang, Tao Liu, Jiantao Wang, Lei Zhao, Baoshan Wang   +8 more
wiley   +1 more source

Multivariate search for differentially expressed gene combinations [PDF]

, 2004
Background To identify differentially expressed genes, it is standard practice to test a two-sample hypothesis for each gene with a proper adjustment for multiple testing. Such tests are essentially univariate and disregard the multidimensional structure
Klebanov Lev, Gordon Alexander, Frisina Robert, Xiao Yuanhui, Yakovlev Andrei   +4 more
core   +2 more sources

Word Recognition for Temporally and Spectrally Distorted Materials:The Effects of Age and Hearing Loss [PDF]

, 2012
Objectives: The purpose of Experiment 1 was to measure word recognition in younger adults with normal hearing when speech or babble was temporally or spectrally distorted.
Abel, Bilger, Buran, Ching, Ching, French, Frisina, Gates, Hargus, Hogan, Humes, Ives, Kamm, Kujawa, MacDonald, Mills, Miranda, Moore, Moore, Pichora-Fuller, Pichora-Fuller, Pichora-Fuller, Pichora-Fuller, Reed, Schneider, Simpson, Souza, Studebaker, Wilson, Wilson, Wilson, Wilson, Wilson   +32 more
core   +1 more source

Ultrastructural Synaptic Differences in the Central Inferior Colliculus in the 3xTG Mouse Across Three Disease Stages

Journal of Comparative Neurology, Volume 533, Issue 12, December 2025.
Symmetric and asymmetric synapses were significantly downregulated by 50% and 20%, respectively, in the aging inferior colliculus of the Alzheimer's 3xTG mouse model during the emerging disease stage (7–8 months). There was no additional significant loss from the emerging disease stage into the established disease stage.
Jeffrey G. Mellott, Lena M. Dellaria, Madeline Guy, Sean R. Hergenrother, Nick J. Tokar, Dakota Z. Smallridge, Miljan Terzic, Jesse W. Young, Christine M. Dengler‐Crish   +8 more
wiley   +1 more source

Functional changes in the human auditory cortex in ageing.

PLoS ONE, 2015
Hearing loss, presbycusis, is one of the most common sensory declines in the ageing population. Presbycusis is characterised by a deterioration in the processing of temporal sound features as well as a decline in speech perception, thus indicating a ...
Oliver Profant, Jaroslav Tintěra, Zuzana Balogová, Ibrahim Ibrahim, Milan Jilek, Josef Syka   +5 more
doaj   +1 more source

CASE REPORT: UNCONTROLLED HYPERTENSION CONTRIBUTES TO WORSENING OF PRESBYCUS SYMPTOMS IN THE ELDERLY

Journal of Community Medicine and Public Health Research, 2020
Presbycusis is a disease that can befall the elderly, caused by a multifactorial process that should be allowed to disrupt communication and social life and cause mental disorders.
Faradila Budi Saputri, Azizah Amimathul Firdha, Safira Rahma, Rieza Rizqy Alda, Syahwina Inayasari, Nyilo Purnami   +5 more
doaj   +1 more source

Quality of life and the benefits of remediation in patients with hearing loss or peripheral vestibular disorders [PDF]

, 2011
This paper presents the effect that hearing loss and Benign Positional Proximal Vertigo (BPPV) have on quality of life and the impact of treatment. The primary purpose of this paper is to critically review the existing literature to determine the effect ...
Miller, Elizabeth
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