Results 151 to 160 of about 24,368 (229)

Presenilin 1 is located in the mitochondrial inner inner membrane and regulates mitochondrial cristae junction protein arrangement and cristae formation in HEK293 cells

Pan You, Pengjin Zhu, Hui Yu, Luwen Wang, Bo Su   +4 more
openalex   +1 more source

Novel Association of the <i>Presenilin-1</i> (Leu282Arg) Mutation with Isolated Spastic Paraparesis: Case Presentation and Review of Current Evidence. [PDF]

J Clin Med
De la Sen-Domínguez M, Delgado-Alvarado M, Torres-Barquin M, Quirce R, Riancho J.   +4 more
europepmc   +1 more source

Case Report: Acute Psychiatric Behavioral Disturbance in a Patient with Presenilin 1 Gene Mutation Associated with Familial Alzheimer's Disease. [PDF]

Neurol Ther
Xia Y, Liu X, Cui W, Zhi Q, Sun Y.
europepmc   +1 more source

Spatiotemporal patterns of gliosis and neuroinflammation in presenilin 1/2 conditional double knockout mice. [PDF]

Front Aging Neurosci, 2022
Peng W, Xie Y, Liao C, Bai Y, Wang H, Li C.   +5 more
europepmc   +1 more source

GPI-1046 Increases Presenilin-1 Expression and Restores NMDA Channel Activity [PDF]

, 2010
Joseph Steiner, K.B. Payne, Christopher Drummond Main, Sabrina D’Alfonso, Kirsten X. Jacobsen, T.P. Hicks, William A. Staines, Michael O. Poulter   +7 more
openalex   +1 more source

Presenilin-1 Familial Alzheimer Mutations Impair γ-Secretase Cleavage of APP Through Stabilized Enzyme-Substrate Complex Formation. [PDF]

Biomolecules
Devkota S, Maesako M, Wolfe MS.
europepmc   +1 more source

Familial Alzheimer's Disease Presenilin 1 Mutations Cause Alterations in the Conformation of Presenilin and Interactions with Amyloid Precursor Protein [PDF]

, 2005
Oksana Berezovska, Alberto Lleó, Lauren Herl, Matthew P. Frosch, Edward A. Stern, Brian J. Bacskai, Bradley T. Hyman   +6 more
openalex   +1 more source

More than a FAD: The In Vivo Effects of Disease-Linked Presenilin-1 Mutations [PDF]

, 2015
Kathleen R. Zahs, Karen H. Ashe
openalex   +1 more source

Mitochondrial dysfunction and Ca²⁺ dysregulation in human iPSC-derived neurons carrying presenilin-1 mutation arise under stress via an MCU-1-independent mechanism. [PDF]

Sci Rep
Wilson C, Galeano P, Remedi MM, Novack GV, Campanelli L, Gastaldi L, Miglietta E, Rossi AH, Olivar N, Brusco LI, Castaño EM, Cáceres A, Morelli L.   +12 more
europepmc   +1 more source

TCR activation stimulates regulated intramembrane proteolysis of L-selectin by presenilin 1 and localized proteasomal degradation of the cytoplasmic tail. [PDF]

J Biol Chem
Moon OR, Newman AC, Alanazi AS, Wehenkel SC, Gawel-Bęben K, Ivetic A, Price DA, Knäuper V, Ager A.   +8 more
europepmc   +1 more source