Results 131 to 140 of about 35,583 (221)

Alzheimer hastalarında presenilin 1 polimorfizmi

, 2020
52
openaire   +1 more source

Presenilin-1 [PDF]

, 2020
openaire   +1 more source

Epigenetic modifications of DNA and RNA in Alzheimer’s disease

Frontiers in Molecular Neuroscience
Alzheimer’s disease (AD) is a complex neurodegenerative disorder and the most common form of dementia. There are two main types of AD: familial and sporadic. Familial AD is linked to mutations in amyloid precursor protein (APP), presenilin-1 (PSEN1), and
Paula Martinez-Feduchi, Peng Jin, Bing Yao   +2 more
doaj   +1 more source

Pleiotropic effects of variants in dementia genes in Parkinson disease [PDF]

, 2018
Benitez, Bruno A, Budde, John, Cooper, Breanna, Cruchaga, Carlos, David, Albert A, Diez-Fairen, Monica, Dube, Umber, Fernandez, Maria V, Ibanez, Laura, Ortega-Cubero, Sara, Pastor, Pau, Perlmutter, Joel S   +11 more
core   +2 more sources

PS1/gamma-secretase acts as rogue chaperone of glutamate transporter EAAT2/GLT-1 in Alzheimer’s disease

Acta Neuropathologica Communications
The recently discovered interaction between presenilin 1 (PS1), a subunit of γ-secretase involved in amyloid-β (Aβ) peptide production, and GLT-1, the major brain glutamate transporter (EAAT2 in the human), may link two pathological aspects of Alzheimer ...
Florian Perrin, Lauren C. Anderson, Shane P. C. Mitchell, Priyanka Sinha, Yuliia Turchyna, Masato Maesako, Mei C. Q. Houser, Can Zhang, Steven L. Wagner, Rudolph E. Tanzi, Oksana Berezovska   +10 more
doaj   +1 more source

The case against presenilin-1 [PDF]

Nature Cell Biology, 1999
openaire   +1 more source

Presenilin-1 (PSEN1) Mutations: Clinical Phenotypes beyond Alzheimer's Disease. [PDF]

Int J Mol Sci, 2023
Yang Y, Bagyinszky E, An SSA.
europepmc   +1 more source

In Silico Phosphoproteomic Analysis Reveals Divergent Regulation of Presenilin 1 and Presenilin 2. [PDF]

Neuromolecular Med
Begum S, De Alvarez JA, Manzoni C, Arber C, Lewis PA.   +4 more
europepmc   +1 more source

Presenilin-1-Derived Circular RNAs: Neglected Epigenetic Regulators with Various Functions in Alzheimer's Disease. [PDF]

Biomolecules, 2023
Sanadgol N, Amini J, Beyer C, Zendedel A.   +3 more
europepmc   +1 more source

Association between basal forebrain volume and age in the presenilin-1 E280A autosomal dominant Alzheimer's disease kindred. [PDF]

Alzheimers Dement
He B, Ospina Lopera P, Espinosa A, Becerra JC, Osorio L, Alzate D, Alvarez S, Grazia A, Teipel SJ, Malotaux V, Tristão-Pereira C, Rowe MC, Giudicessi A, Su Y, Chen Y, Do Carmo S, Aguillón D, Cuello AC, Quiroz YT.   +18 more
europepmc   +1 more source