Results 141 to 150 of about 24,368 (229)

Evaluation of the relationship among gene expressions and enzyme activities with antioxidant role and presenilin 1 expression in Alzheimer's disease. [PDF]

J Cell Mol Med, 2023
Işık M, Tunç A, Duran HE, Naldan ME, Yılmaz A, Koçak MN, Beydemir Ş.   +6 more
europepmc   +1 more source

Presenilin 1 E280A mutation induces dysfunctional astrocytic phenotype in menstrual stromal-derived astrocyte-like cells. [PDF]

Cell Mol Life Sci
Correa NQ, Mendivil-Perez M, Velez-Pardo C, Jimenez-Del-Rio M, Quiroz-Correa Q.   +4 more
europepmc   +1 more source

Human Presenilin-1 delivered by AAV9 rescues impaired γ-secretase activity, memory deficits, and neurodegeneration in Psen mutant mice. [PDF]

Proc Natl Acad Sci U S A, 2023
Montenegro P, Chen P, Kang J, Lee SH, Leone S, Shen J.   +5 more
europepmc   +1 more source

Plasma p-tau231 in the presenilin 1 E280A autosomal dominant Alzheimer's disease kindred: A cross-sectional and longitudinal cohort study. [PDF]

Alzheimers Dement
Malotaux V, Ashton NJ, Öhrfelt A, Chen Y, Su Y, Garcia-Ospina G, Guzman-Martínez C, Villegas-Lanau A, Gómez-Ramirez J, Giraldo-Chica M, Aguillon D, Tirado V, Baena A, Munoz C, Acosta-Baena N, Pruzin JJ, Ghisays V, Rios-Romenets S, Vila-Castelar C, Martínez JE, Giudicessi A, Tariot PN, Zetterberg H, Blennow K, Reiman EM, Quiroz YT.   +25 more
europepmc   +2 more sources

Genetic influences on white matter and metabolism abnormal change in Alzheimer’s disease: Meta-analysis for neuroimaging research on presenilin 1 mutation

, 2018
Xiaochun Gu, Tao Chu, Li Liu, Xiao Han
openalex   +1 more source

Age-Dependent Impairment of Spine Morphology and Synaptic Plasticity in Hippocampal CA1 Neurons of a Presenilin 1 Transgenic Mouse Model of Alzheimer's Disease [PDF]

, 2009
Alexandra Auffret, Vanessa Gautheron, Mariaelena Repici, Rudolf Kraftsik, Howard T.J. Mount, Jean Mariani, Catherine Rovira   +6 more
openalex   +1 more source

β-Sitosterol treatment attenuates cognitive deficits and prevents amyloid plaque deposition in amyloid protein precursor/presenilin 1 mice [PDF]

, 2020
Jian-Ya Ye, Li Li, Qing-Mao Hao, Yong Qin, Changsheng Ma   +4 more
openalex   +1 more source

Molecular basis for isoform-selective inhibition of presenilin-1 by MRK-560. [PDF]

Nat Commun, 2022
Guo X, Wang Y, Zhou J, Jin C, Wang J, Jia B, Jing D, Yan C, Lei J, Zhou R, Shi Y.   +10 more
europepmc   +1 more source

Glial and Neuronal Alzheimer's Disease-Related Alterations Reproduced in Human Induced Pluripotent Stem Cells With Presenilin-1 Mutation [PDF]

Davide Comolli, Elisa Murari, Milica Cerovic, Liviu Soltuzu, Wenjie Liao, Aurora Bianchi, Serena Seminara, Ilaria Craparotta, Stefano Fumagalli, Claudia Balducci, Gianluigi Forloni, Massimiliano De Paola   +11 more
openalex   +1 more source

Genetics, Functions, and Clinical Impact of Presenilin-1 (PSEN1) Gene. [PDF]

Int J Mol Sci, 2022
Bagaria J, Bagyinszky E, An SSA.
europepmc   +1 more source