Results 141 to 150 of about 35,583 (221)

Increasing expression of presenilin 1, β-catenin, and p-PTEN and its regulatory roles on cell invasion in gastric cancer. [PDF]

World J Gastrointest Oncol
Lin X, Lin GF, Gu FT, Li YL.
europepmc   +1 more source

APP Deficiency Ameliorates FAD Presenilin 1 F105C and A246E Mutations-induced Mitochondrial Dysfunction in Human Cortical Neurons. [PDF]

Int J Biol Sci
Yen YH, Yuan F, Tang D, Luo JF, Ming C, Kang PJ, Su H, Chong CM, Zhang SC.   +8 more
europepmc   +1 more source

Presenilin-1 C779T Mutation Presenting With Rapidly Progressive Dementia and Medial Temporal Lobe MRI Changes. [PDF]

Case Rep Neurol Med
Toccaceli Blasi M, Borioni MS, Nuti F, Belvisi D, Canevelli M, Fabbrini G, Bruno G.   +6 more
europepmc   +1 more source

Evaluation of the relationship among gene expressions and enzyme activities with antioxidant role and presenilin 1 expression in Alzheimer's disease. [PDF]

J Cell Mol Med, 2023
Işık M, Tunç A, Duran HE, Naldan ME, Yılmaz A, Koçak MN, Beydemir Ş.   +6 more
europepmc   +1 more source

Plasma p-tau231 in the presenilin 1 E280A autosomal dominant Alzheimer's disease kindred: A cross-sectional and longitudinal cohort study. [PDF]

Alzheimers Dement
Malotaux V, Ashton NJ, Öhrfelt A, Chen Y, Su Y, Garcia-Ospina G, Guzman-Martínez C, Villegas-Lanau A, Gómez-Ramirez J, Giraldo-Chica M, Aguillon D, Tirado V, Baena A, Munoz C, Acosta-Baena N, Pruzin JJ, Ghisays V, Rios-Romenets S, Vila-Castelar C, Martínez JE, Giudicessi A, Tariot PN, Zetterberg H, Blennow K, Reiman EM, Quiroz YT.   +25 more
europepmc   +2 more sources

Presenilin 1 E280A mutation induces dysfunctional astrocytic phenotype in menstrual stromal-derived astrocyte-like cells. [PDF]

Cell Mol Life Sci
Correa NQ, Mendivil-Perez M, Velez-Pardo C, Jimenez-Del-Rio M, Quiroz-Correa Q.   +4 more
europepmc   +1 more source

Human Presenilin-1 delivered by AAV9 rescues impaired γ-secretase activity, memory deficits, and neurodegeneration in Psen mutant mice. [PDF]

Proc Natl Acad Sci U S A, 2023
Montenegro P, Chen P, Kang J, Lee SH, Leone S, Shen J.   +5 more
europepmc   +1 more source

Molecular basis for isoform-selective inhibition of presenilin-1 by MRK-560. [PDF]

Nat Commun, 2022
Guo X, Wang Y, Zhou J, Jin C, Wang J, Jia B, Jing D, Yan C, Lei J, Zhou R, Shi Y.   +10 more
europepmc   +1 more source

Genetics, Functions, and Clinical Impact of Presenilin-1 (PSEN1) Gene. [PDF]

Int J Mol Sci, 2022
Bagaria J, Bagyinszky E, An SSA.
europepmc   +1 more source

Novel Association of the <i>Presenilin-1</i> (Leu282Arg) Mutation with Isolated Spastic Paraparesis: Case Presentation and Review of Current Evidence. [PDF]

J Clin Med
De la Sen-Domínguez M, Delgado-Alvarado M, Torres-Barquin M, Quirce R, Riancho J.   +4 more
europepmc   +1 more source