Results 121 to 130 of about 24,368 (229)

The Proteolytic Fragments of the Alzheimer's Disease-associated Presenilin-1 Form Heterodimers and Occur as a 100–150-kDa Molecular Mass Complex [PDF]

, 1998
Anja Capell, Jürgen Grünberg, Brigitte Pesold, Anke Diehlmann, Martin Citron, Ralph A. Nixon, Konrad Beyreuther, Dennis J. Selkoe, Christian Haass   +8 more
openalex   +1 more source

Correction: Lack of a site-specific phosphorylation of Presenilin 1 disrupts microglial gene networks and progenitors during development

, 2021
José Henrique Ledo, Ran Zhang, Luka Mesin, Diego Mourão‐Sá, Estefania P. Azevedo, Hernandez Moura Silva, Olga G. Troyanskaya, Victor Bustos, Paul Greengard   +8 more
openalex   +2 more sources

Neurodegeneration in Alzheimer Disease: Role of Amyloid Precursor Protein and Presenilin 1 Intracellular Signaling [PDF]

, 2012
Mario Nizzari, Stefano Thellung, Alessandro Corsaro, Valentina Villa, Aldo Pagano, Carola Porcile, Claudio Russo, Tullio Florio   +7 more
openalex   +1 more source

PS1/gamma-secretase acts as rogue chaperone of glutamate transporter EAAT2/GLT-1 in Alzheimer’s disease

Acta Neuropathologica Communications
The recently discovered interaction between presenilin 1 (PS1), a subunit of γ-secretase involved in amyloid-β (Aβ) peptide production, and GLT-1, the major brain glutamate transporter (EAAT2 in the human), may link two pathological aspects of Alzheimer ...
Florian Perrin, Lauren C. Anderson, Shane P. C. Mitchell, Priyanka Sinha, Yuliia Turchyna, Masato Maesako, Mei C. Q. Houser, Can Zhang, Steven L. Wagner, Rudolph E. Tanzi, Oksana Berezovska   +10 more
doaj   +1 more source

Bax inhibitor 1 is a γ-secretase–independent presenilin-binding protein [PDF]

, 2018
Shenjie Wu, Wenqi Song, Catherine C. L. Wong, Yigong Shi   +3 more
openalex   +1 more source

Presenilin-1 Regulates Intracellular Trafficking and Cell Surface Delivery of β-Amyloid Precursor Protein [PDF]

, 2003
Dongming Cai, Jae Yoon Leem, Jeffrey P. Greenfield, Pei Wang, Benny S. Kim, Runsheng Wang, Kryslaine O. Lopes, Seong‐Hun Kim, Hui Zheng, Paul Greengard, Sangram S. Sisodia, Gopal Thinakaran, Huaxi Xu   +12 more
openalex   +1 more source

Presenilin-1 (PSEN1) Mutations: Clinical Phenotypes beyond Alzheimer's Disease. [PDF]

Int J Mol Sci, 2023
Yang Y, Bagyinszky E, An SSA.
europepmc   +1 more source

Contribution of the γ-Secretase Subunits to the Formation of Catalytic Pore of Presenilin 1 Protein [PDF]

, 2012
Koji Takeo, Naoto Watanabe, Taisuke Tomita, Takeshi Iwatsubo   +3 more
openalex   +1 more source

In Silico Phosphoproteomic Analysis Reveals Divergent Regulation of Presenilin 1 and Presenilin 2. [PDF]

Neuromolecular Med
Begum S, De Alvarez JA, Manzoni C, Arber C, Lewis PA.   +4 more
europepmc   +1 more source

Prostaglandin I ₂ upregulates the expression of anterior pharynx‐defective‐1α and anterior pharynx‐defective‐1β in amyloid precursor protein/presenilin 1 transgenic mice [PDF]

, 2016
Pu Wang, Pei‐Pei Guan, Jingwen Guo, Long‐Long Cao, Guo‐Biao Xu, Xin Yu, Yue Wang, Zhan‐You Wang   +7 more
openalex   +1 more source