Results 181 to 190 of about 24,368 (229)

Impaired Skeletal Development by Disruption of Presenilin-1 in Pigs and Generation of Novel Pig Models for Alzheimer's Disease. [PDF]

J Alzheimers Dis
Uh K, Monarch K, Reese ED, Rodriguez K, Yoon J, Spate LD, Samuel MS, Koh S, Chen PR, Jarome TJ, Allen TA, Prather RS, Lee K.   +12 more
europepmc   +1 more source

Cognitive Outcomes in Autosomal-Dominant Alzheimer's Disease: A Comprehensive Review from a Colombian Kindred with the Presenilin-1 E280A Mutation. [PDF]

J Alzheimers Dis
Giudicessi A, McDowell CP, Martinez JE, Baena A, Vila-Castelar C, Norton D, Aguirre-Acevedo DC, Tirado V, Bocanegra Y, Guzman-Velez E, Lopera F, Cronin-Golomb A, Quiroz YT.   +12 more
europepmc   +1 more source

Engineered Exosomes Containing microRNA-29b-2 and Targeting the Somatostatin Receptor Reduce Presenilin 1 Expression and Decrease the β-Amyloid Accumulation in the Brains of Mice with Alzheimer's Disease. [PDF]

Int J Nanomedicine
Lin EY, Hsu SX, Wu BH, Deng YC, Wuli W, Li YS, Lee JH, Lin SZ, Harn HJ, Chiou TW.   +9 more
europepmc   +1 more source

Distribution and pathophysiological role of amyloid precursor protein and presenilin 1 : Characterization in rats and in vitro studies on the pathogenic arctic mutation

, 2002
Camilla Nilsberth
openalex  

Effect of Linalool, Cineole, and β-Bourbonene Coupled with Aerobic Training on the Improvement of Presenilin-1/Amyloid Protein Precursor/Interleukin-1 beta/CASPASE 1 Network, Oxidative Capacity, and miRNA-210 in Mice with Alzheimer's Disease. [PDF]

Arch Razi Inst
Alimoradi Z, Taghian F, Jalali Dehkordi K.   +2 more
europepmc   +1 more source

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Regulation of Apoptosis by Presenilin 1

Neurobiology of Aging, 1998
Familial Alzheimer's disease is transmitted as an autosomal dominant disorder and, in 5-10% of the cases, is caused by mutations in the coding regions of two homologous genes, Presenilin 1 and 2 (PS1 and PS2). Previously, we have shown that PS2, a homolog of PS1.
B, Wolozin, P, Alexander, J, Palacino
openaire   +2 more sources

Presenilin-1 in Neuroblastoma Cells

Toxicology in Vitro, 1998
Presenilin-1 expression was investigated in Neuro-2a cells using the alphaPS1Loop antibody. The bulk of the immunoreactivity was found as the approximately 18kDa C-terminal fragment. Hydrogen peroxide treatment of the Neuro-2a cells for 24 hours resulted in a concentration-dependent cytotoxicity with a critical concentration of hydrogen peroxide of ...
C, Lindblad, H, Hedin, G, Andersson, C J, Fowler   +3 more
openaire   +2 more sources