Results 101 to 110 of about 3,722,975 (358)

Tannin resin-boron associations: Leaching and biological resistance [PDF]

, 2012
The easy leaching of boron in wood preservation formulations has allowed to use this fungicide only for short term applications. The recently discovered adduct with flavonoids allows boron to resist longer periods of time within wood and consequently ...
Leménager, Nicolas, Petutschnigg, Alexander, Pizzi, Antonio, Thévenon, Marie-France, Tondi, Gianluca, Wieland, Stefanie   +5 more
core  

ATR is essential for preservation of cell mechanics and nuclear integrity during interstitial migration

Nature Communications, 2020
ATR responds to mechanical stress at the nuclear envelope and mediates envelope-associated repair of aberrant topological DNA states. By combining microscopy, electron microscopic analysis, biophysical and in vivo models, we report that ATR-defective ...
G. Kidiyoor, Qingsen Li, G. Bastianello, Christopher Bruhn, Irene Giovannetti, Adhil Mohamood, G. Beznoussenko, A. Mironov, M. Raab, M. Piel, Umberto Restuccia, V. Matafora, A. Bachi, S. Barozzi, D. Parazzoli, E. Frittoli, A. Palamidessi, T. Panciera, S. Piccolo, G. Scita, P. Maiuri, K. Havas, Zhong-Wei Zhou, Amit Kumar, J. Bartek, Zhao-Qi Wang, M. Foiani   +26 more
semanticscholar   +1 more source

Cell‐free DNA aneuploidy score as a dynamic early response marker in prostate cancer

Molecular Oncology, EarlyView.
mFast‐SeqS‐based genome‐wide aneuploidy scores are concordant with aneuploidy scores obtained by whole genome sequencing from tumor tissue and can predict response to ARSI treatment at baseline and, at an early time point, to ARSI and taxanes. This assay can be easily performed at low cost and requires little input of cfDNA. Cell‐free circulating tumor
Khrystany T. Isebia, Anouk C. de Jong, Lisanne F. van Dessel, Vanja de Weerd, Corine Beaufort, Jean Helmijr, José Alberto Nakauma‐González, Job van Riet, Paul Hamberg, Daniel Vis, Michiel S. van der Heijden, Nick Beije, Martijn P. Lolkema, Teoman Deger, Saskia M. Wilting, Ronald de Wit, Maurice P. H. M. Jansen, John W. M. Martens   +17 more
wiley   +1 more source

Function-preserving Filters for Sampling in Biological Networks

Procedia Computer Science, 2012
AbstractAssays created to study systems of disease and aging can offer a whole new set of therapeutic targets. However, with experiments of this immense volume, data becomes unmanageable for many traditional analyses. Enter the biological network, a tool for modeling relationships among high-throughput data that is quickly rising in popularity.
Kathryn Dempsey, Kathryn Dempsey, Hesham Ali, Hesham Ali, Sanjukta Bhowmick   +4 more
openaire   +2 more sources

Molecular and functional profiling unravels targetable vulnerabilities in colorectal cancer

Molecular Oncology, EarlyView.
We used whole exome and RNA‐sequencing to profile divergent genomic and transcriptomic landscapes of microsatellite stable (MSS) and microsatellite instable (MSI) colorectal cancer. Alterations were classified using a computational score for integrative cancer variant annotation and prioritization.
Efstathios‐Iason Vlachavas, Konstantinos Voutetakis, Vivian Kosmidou, Spyridon Tsikalakis, Spyridon Roditis, Konstantinos Pateas, Ryangguk Kim, Kymberleigh Pagel, Stephan Wolf, Gregor Warsow, Antonia Dimitrakopoulou‐Strauss, Georgios N. Zografos, Alexander Pintzas, Johannes Betge, Olga Papadodima, Stefan Wiemann   +15 more
wiley   +1 more source

Fossil biomass preserved as graphitic carbon in a late paleoproterozoic banded iron formation metamorphosed at more than 550°C [PDF]

, 2019
Metamorphism is thought to destroy microfossils, partly through devolatilization and graphitization of biogenic organic matter. However, the extent to which there is a loss of molecular, elemental and isotope signatures from biomass during high ...
De Gregorio, BT, Drost, M, Kilcoyne, DA, Marbach, H, Nittler, L, Papineau, D, Sagar, J, Thornton, G, Thorogate, R, Wang, J   +9 more
core   +2 more sources

A review of analytical methods for assessing preservation in waterlogged archaeological wood and their application in practice

Heritage Science, 2020
Waterlogged archaeological wood can present management challenges due to its vulnerability to chemical and biological decay, both during burial and post-excavation.
Kirsty E. High, K. Penkman
semanticscholar   +1 more source

Stochastic variation in the FOXM1 transcription program mediates replication stress tolerance

Molecular Oncology, EarlyView.
Cellular heterogeneity is a major cause of drug resistance in cancer. Segeren et al. used single‐cell transcriptomics to investigate gene expression events that correlate with sensitivity to the DNA‐damaging drugs gemcitabine and prexasertib. They show that dampened expression of transcription factor FOXM1 and its target genes protected cells against ...
Hendrika A. Segeren, Kathryn A. Wierenga, Frank M. Riemers, Elsbeth A. van Liere, Bart Westendorp   +4 more
wiley   +1 more source

Notes on Contraction Theory

, 2005
These notes derive a number of technical results on nonlinear contraction theory, a comparatively recent tool for system stability analysis. In particular, they provide new results on the preservation of contraction through system combinations, a ...
Slotine, Jean-Jacques, Tabareau, Nicolas
core   +3 more sources

Setting people in their environment: plant and animal remains from Anglo-Scandinavian York [PDF]

, 2004
INTRODUCTION: For the past millennium, the inhabitants of the centre of York have, whether hey knew it or not, been living on top of a compost heap in which are preserved all kinds of remains of Anglo-Scandinavian and early post-conquest life.
Hall, A., Kenward, H.
core