Results 61 to 70 of about 3,827,941 (337)

Organoids in pediatric cancer research

FEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Advances in the Application of Plant Chromosome Rearrangement in Crop Genetic Improvement

Guangdong nongye kexue
Chromosome rearrangement is a mechanism that can lead to the loss, duplication, translocation and inversion of DNA segments, thereby altering the genomic structure and providing possibilities for creating new variable traits.
Jiao XUE, Qingfeng ZHU, Pei CHEN, Yanzhao FENG, Yang YU   +4 more
doaj   +1 more source

By dawn or dusk—how circadian timing rewrites bacterial infection outcomes

FEBS Letters, EarlyView.
The circadian clock shapes immune function, yet its influence on infection outcomes is only beginning to be understood. This review highlights how circadian timing alters host responses to the bacterial pathogens Salmonella enterica, Listeria monocytogenes, and Streptococcus pneumoniae revealing that the effectiveness of immune defense depends not only
Devons Mo, Catherine S. Palmer, Jacqueline M. Kimmey   +2 more
wiley   +1 more source

Research Progress on the Regulation of Important Agronomic Traits in Crops by Non-coding Genetic Resources

Guangdong nongye kexue
In traditional crop genetics research, protein-coding genes have always been the primary focus. However, recent scientific advances have revealed the critical role of non-coding genetic resources in regulating key agronomic traits such as crop yield ...
Yang YU, Qingfeng ZHU, Jiao XUE, Pei CHEN, Yanzhao FENG   +4 more
doaj   +1 more source

Biominerals - source and inspiration for novel advanced materials [PDF]

, 1991
Biomineralization seems an odd sort of word. How can you combine biology and minerals? However, a quick look around brings to light many familiar objects that are examples of biominerals.
Evans, L.A., Macey, D.J., St Pierre, T.G., Webb, J.   +3 more
core   +1 more source

Transcriptomic signatures of neuronal differentiation and their association with risk genes for autism spectrum and related neuropsychiatric disorders. [PDF]

, 2016
Genes for autism spectrum disorders (ASDs) are also implicated in fragile X syndrome (FXS), intellectual disabilities (ID) or schizophrenia (SCZ), and converge on neuronal function and differentiation. The SH-SY5Y neuroblastoma cell line, the most widely
Chiocchetti, AG, Cocchi, E, de la Torre-Ubieta, L, Freitag, CM, Fulda, S, Geschwind, DH, Haslinger, D, Lindlar, S, Rothämel, T, Stein, JL, Waltes, R   +10 more
core   +1 more source

Progress on the Extraction, Separation, Biological Activity, and Delivery of Natural Plant Pigments

Molecules, 2023
Natural plant pigments are safe and have low toxicity, with various nutrients and biological activities. However, the extraction, preservation, and application of pigments are limited due to the instability of natural pigments. Therefore, it is necessary
Xianwen Lu, Wenjun Li, Qi Wang, Jing Wang, Song Qin   +4 more
semanticscholar   +1 more source

Hematopoietic (stem) cells—The elixir of life?

FEBS Letters, EarlyView.
The aging of HSCs (hematopoietic stem cells) and the blood system leads to the decline of other organs. Rejuvenating aged HSCs improves the function of the blood system, slowing the aging of the heart, kidney, brain, and liver, and the occurrence of age‐related diseases.
Emilie L. Cerezo, Jonah Anderson, Emilie Dinh Vedrenne, Noël Yeh Martín, Jette Lengefeld   +4 more
wiley   +1 more source

DNA Methylation-Based Panel Predicts Survival of Patients With Clear Cell Renal Cell Carcinoma and Its Correlations With Genomic Metrics and Tumor Immune Cell Infiltration

Frontiers in Cell and Developmental Biology, 2020
DNA methylation based prognostic factor for patients with clear cell renal cell carcinoma (ccRCC) remains unclear. In the present study, we identified survival-related DNA methylation sites based on the differentially methylated DNA CpG sites between ...
Xiao-Ping Liu, Lingao Ju, Lingao Ju, Chen Chen, Chen Chen, Tongzu Liu, Sheng Li, Sheng Li, Xinghuan Wang   +8 more
doaj   +1 more source

The Genomic HyperBrowser: inferential genomics at the sequence level [PDF]

, 2010
The immense increase in the generation of genomic scale data poses an unmet analytical challenge, due to a lack of established methodology with the required flexibility and power. We propose a first principled approach to statistical analysis of sequence-
Clancy, Trevor, Ferkingstad, Egil, Frigessi, Arnoldo, Glad, Ingrid K., Gundersen, Sveinung, Holden, Lars, Holden, Marit, Hovig, Eivind, Johansen, Morten, Liestøl, Knut, Nygaard, Vegard, Rydbeck, Halfdan, Sandve, Geir K., Tøstesen, Eivind   +13 more
core   +3 more sources